FEEDING, HANDLING & ASSEMBLING
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DISPOSABLE PRE-FILLED SYRINGES FEEDING, HANDLING & ASSEMBLING

01 | FEEDING 9 BULK FEEDING | AVS SERIES DE-NESTING | NEXTRAN10 RE-NESTING | NEXTRAN15 DE-TRAYING | NEXTRAT20 RE-TRAYING | NEXTRAT25 03 | ASSEMBLING 17 LABELLING | COMBI-1LAB 18 PLUNGERING & LABELLING | COMBI-2PL 19 PLUNGERING, LABELLING & BACKSTOP ASSEMBLING | COMBI-3BS 20 SAFETY DEVICE ASSEMBLING | COMBI-1SD/2SD 21 PLUNGERING, LABELLING & SAFETY DEVICE ASSEMBLING | COMBI-3SD/4SD 22 NO GLASS-TO-GLASS CONTACT

WE AT MARCHESINI ARE PROUD LEADERS IN MANUFACTURING AND INTEGRATING COMPLETE LINES SINCE 1974. WE PRODUCE STAND-ALONE MACHINES AND COMPLETE LINES TO HANDLE THE ENTIRE PACKAGING PROCESS FOR THE PHARMACEUTICAL AND COSMETIC INDUSTRIES. Following the acquisition of CO.RI.MA. in 2003, we became a leading company offering complete lines for injectable products in pre-filled syringes, vials and ampoules, from the washing process of the primary container to resting the final packed product on the pallet. The Marchesini Group combines CO.RI.MA’s proven experience in disposable Pre-Filled Syringe...

Long-standing experience in syringe handling machinery both with Innovative solutions enable multiple component assembling in R&D department. High-speed machines NO-Contact arrangement. Feeding, Handling and Assembling machines Assembling machines can be integrated with Robotized Stations which have been developed internally, enabling are constantly developed in our in-house No Glass-toGlass Contact syringe handling between flanges and improving line efficiency. provide solutions aimed at reducing total changeover time and maximizing the pharmaceutical process performance. which have been...

DISPOSABLE PRE-FILLED SYRINGES PACKAGING PROCESS PRIMARY PACKAGING HANDLING & ASSEMBLING VISUAL INSPECTION (machine by third party) RENESTING/ RETRAYING TRAYS PACKAGING INTO CARTON DENESTING/ DETRAYING BACKSTOP ASSEMBLING V PACKAGING PACKAGING I INTO INTO S BUNDLING WRAPPING PLASTIC U PAPERBOA TRAYS ARD TRAYS L DENESTING/ DETRAYING SECONDARY PACKAGING SAFETY DEVICE ASSEMBLING LABELLING LABELLING The above chart illustrates the complete Marchesini line, whereas the contents of this catalogue detail the handling and assembling machines. For information on secondary packaging and end of line...

BULK FEEDING AVS SERIES Elevator with Plates for automatic feeding of syringes or similar objects. • 12 mobile plates driven by an independent motor • Unload conveyor driven by an independent motor with step-less speed adjustment • Integrated high-capacity pre-feeding hopper, driven by an independent motor • Complete, easy and quick emptying and cleaning of the elevating plates area and pre-feeding hopper • Possibility to integrate the AVS on the downstream machine or make it an independent unit equipped by its own control system and HMI display OUTPUT Up to 36.000 pcs /h PRODUCT RANGE...

DE-NESTING NEXTRAN10 Automatic machine for syringe extraction from Nest and transferring to downstream process. • Infeed Tub buffering with FIFO policy • Decoding of Pre-printed data on the Tub by a vision system • Automated Nest Removal from Tub • Empty Tub and Nest stacking units • Gentle transfer of syringes onto the unload guide • Also available in No Glass-To-Glass Contact version • For automated Inspection Lines: Empty Nest re-positioning on Tub with empty Nest automatically transferred to down-stream Re-Nesting machine (e.g. bridged conveyor) OUTPUT Up to 36.000 syringes / h PRODUCT...

MACHINE SOLUTIONS RE-NESTING NEXTRAN15 Automatic machine for re-arranging inspected syringes into the Nest. • Robotized re-nesting is carried out with the Nest already placed in the Tub, making the machine very compact • Possibility of automatic Tub/Nest loading from the de-nester with a “bridge conveyor” • Vision check for Nest completeness • Data printing on the Tub (“direct imprint” or “print & apply labelling”) • Also available in No Glass-To-Glass Contact version OUTPUT Up to 36.000 syringes / hPRODUCT RANGE Syringes 0,5 / 20 m

DE-TRAYING NEXTRAT20 Automatic machine for syringes or safety devices feeding from Rondo-Tray. • High capacity loading system for stacked trays, designed to guarantee the stability of narrow Tray stacks • Vision system control for load orientation and Tray rotation • Gentle removal of Syringe or Safety Device by star-wheel or robot (for No-Contact version) • Empty Tray stacking unit OUTPUT Up to 24.000 syringes / hPRODUCT RANGE Syringes, Safety Devices and other hangable objects supplied in trays Made by Cori

MACHINE SOLUTIONS RE-TRAYING NEXTRAT25 Automatic machine for re-arranging inspected syringes into Rondo-Trays. • Automatic Loading of stacked empty Trays (all arranged with the same orientation) • Walking-beam continuous re-traying by robot, with rondo-tray running in horizontal position • Vision check for Tray completeness • Automatic rejection of incomplete Trays • Full Tray stacking • Also available in No Glass-To-Glass Contact version OUTPUT Up to 24.000 syringes / hPRODUCT PRODUCT RANGE Syringes 0,5 / 20 ml Made by

LABELLING COMBI-1LAB Automatic, continuous motion machine for syringes or Safety Device labelling. • Objects are processed to avoid contact with machine’s metal components • Highly flexible feeding & unloading sections • Customizable Label Feeding, Printing and Dispensing system • In Process Controls (IPC) performed by sensors and vision systems • Individual counting for each reject type • Also available in No Glass-To-Glass Contact version OUTPUT Up to 36.000 syringes / h PRODUCT RANGE Syringes 0,5 ml / 20 ml Round-shaped Safety Devices Made by

MACHINE SOLUTIONS PLUNGERING & LABELLING COMBI-2PL Automatic, continuous motion machine for syringe plungering and labelling. As well as the COMBI-1LAB features: • Syringe loading by adjustable motorized rollers without format-change • Universal Plunger rod sorting unit (format-change free), with integrated high capacity pre-feeder • Single adjustment (manual or motorized) of the plunger-rod feeding and assembling system according to rubber stopper position • Plunger rod release & re-grabbing system to compensate stopper position variability • Dynamic centering during Plunger Rod insertion...