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SPHERO PFS

Product catalog summary

Overview: The SPHERO® PFS is a melt pelletizer designed for creating spherical particles, specifically tailored for pharmaceutical applications. It offers an enclosed system that ensures containment and produces pellets with a narrow size distribution and homogeneous shape, enhancing flowability and reducing dust.

Benefits:

Enclosed system for containment.
Narrow particle size distribution.
Homogeneous pellet shape for improved flowability.
Quick and easy cleaning process.
Low-dust pelletizing suitable for brittle formulations.
Special design for sticky product pelletizing.
Facilitates quicker development of innovative pharmaceutical formulations.

Applications:

Wet extrusion process for water-soluble carrier/active ingredient combinations.
Micro-pellets for tamper-resistant and abuse-deterrent formulations.
Production of Multiple Unit Pellet System (MUPS) tablets.
Supports continuous operation or batch production.
Suitable for highly potent active pharmaceutical ingredients.
Pelletizing from an extruder or reactor vessel.

Technical Data:

Model: SPHERO® 70
Number of holes: 1-12
Throughput: 0.3-20 kg/h
Pellet size: 0.5-5 mm
Number of blades: 2-9

Die-plate Features:

Composed of a support ring and exchangeable plate.
Standard material: tungsten carbide, with other options available.
Integrated product temperature sensor.

Cutting Chamber Features:

Product wetted components are easily exchangeable.
Integrated cooling duct with water flow.
Cutting chamber interlock and temperature sensor for process air.
Few and easily exchangeable sealings.
Integrated air pressure sensor at the chamber outlet.
Easy dismantling and cleaning.

Suitable Pump: extrex® 20 to 36 GP

Operational Parameters:

Maximum differential pressure: 250 bar
Temperature range: 30° to 200°C

Catalog excerpts

SPHERO® PFS Melt pelletizer for spherical particles ©> AUTOMATIK The pelletizing system, thanks to its enclosed design, is ideal for pelletizing carrier/agent combinations in hot-melt extrusion processes ■ manufacture of pharmaceutical products. ■ Enclosed system (containment) Narrow distribution of particle size Homogeneous pellet shape featuring great flowability Quick and easy to clean Low-dust pelletizing Pelletizing of brittle formulations Special design for pelletizing sticky products Simplified, quicker development of innovative pharmaceutical formulation

Open the catalog to page 1

Application: Wet extrusion process ■ Pelletizing of water-soluble carrier/active ingredient combination ■ Micro-pellets for tamper-resistant and abuse-deterrent formulation ■ Production of MUPS (Multiple Unit Pellet System) tablets ■ Continuous operation or batch production ■ Highly potent active pharmaceutical ingredients ■ For pelletizing from an extruder or reactor vessel Technical Data SPHERO® 70 No. of holes: Throughput: Pellet size: Number of blades: Suitable Pump extrex® 20 to 36 GP Differential Pressure Ap: max. 250 bar Die-plate ■ Composed of support ring and exchangeable plate ■ Standard...

Open the catalog to page 2

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