Continuous Extrusion Equipment Meeting the Requirements Extruder SoLutioifProVldeg LEMIX EXTRUSION TECHNOLOGY © Plant D, No.329, Guifeng Road, Xinhui District,Jiangmen City, Guangdong Province, PR China @ T +86 750 6620869 (0) M +86-133 8217 2388 © [email protected] © [email protected] f| www.extruder-service.com © www.lemixtec.com

Founded in 2015, Lemix is a professional manufacturer focusing on R&D, production and service of extrusion equipment. Since 2026 year, we have two factories which covers an area around 10,000 square meters. Our core business covers twin-screw extruders, hot-melt extruders, screw cleaning & disassembly machines, cooling system cleaners and barrel wear detectors. We also supply key spare parts including screw elements, barrels, shafts and gearboxes, together with full maintenance, repair and upgrade services. In addition, we import high-performance stainless steel and provide customized material...

CONTINUOUS EXTRUSDN EQUIPMENT MEETING THE REQUIREMENTS OF THE PHARMACEUTICAL INDUSTRY PHARMACEUTICAL EXTRUSION CONTINUOUS EXTRUSION EQUIPMENT MEETING THE REQUIREMENTS OF THE PHARMACEUTDAL INDUSTRY

Hot Melt Extrusion (HME) is a process for dispersing Active Pharmaceutical Ingredients (APIs) into polymers. Commonly used polymeric carriers in the pharmaceutical industry include PVP, methacrylates, or cellulose-based carrier materials. During the hot melt extrusion process, mixtures of APIs, polymers and excipients are processed under specific temperature and pressure conditions. The PROMIX series equipment homogenizes all materials, while high shear forces disperse the drug in the polymer carrier at the molecular level, forming a solid dispersion state. The extrudate exiting the extrusion...

Twin-screw Extruder ConfigurationContinuous Extrusion Process Extrusion technology is a recognized continuous manufacturing process in the pharmaceutical industry, which offers distinct advantages over batch production. In an extruder, many process steps are integrated, including feeding, melting, venting, and discharging. Upstream material handling and downstream equipment are connected with the extruder to complete the production operation. Below is a typical twin-screw extruder configuration. Integration of several process stages in one single unit Compact footprint even for high-capacity...

Process CoraThe core principle of the extruder The process treatment unit is the heart of the extruder. The modular design of the barrel and screws provides high process flexibility. The processing length (number of barrels) generally depends on the process route. A typical processing length for hot melt extrusion is 40D. For some wet granulation or wet extrusion processes, the processing length is only 20D. The first barrel section is non-heatable to prevent clogging at the feeding zone caused by excessive material viscosity.Subsequent barrel sections are equipped with electric heating and water...

PROMIX-26S The Lemix Promix series of extruders covers the full capacity range from laboratory scale to batch production. Our laboratory setup for process development is fully equipped. Technical Advantages H GMP-compliant product design H Technical support from an R&D team and process experts with academic expertise n Control unit compliant with 21 CFR Part 11 n Quality certification Technical Specifications *AII specifications are subject to actual delivery. PROMIX-ll Diameter Maxscrew speed Specific torque *AII specifications are subject to actual delivery. PROMIX-32S Diameter Motor power...

Easy to clean, multi-functional GMP compliant for operation and monitoring In response to the high standards required for equipment in the pharmaceutical industry, Lemix can provide a full range of GMP-compliant extrusion equipment, including auxiliary machines.lt meets all GMP requirements concerning cleaning, spare parts, materials of construction, surface finish, and material qualification documentation. The CIP cleaning kit simplifies cleaning operations. Insert the cleaning hose into the adapter port and flush the screw and barrel (stainless steel) with water. The screw elements and barrel...

Customers can choose the appropriate melt forming method according to their own materials and formulation processes. After the hot-melt extrusion process, the key step is material cooling. Equipment configuration requirements may vary depending on the product formulation. The most common method uses a conveyor belt for natural air cooling. More efficient horizontal or vertical water bath cooling units are also available options. Pelletization (Micro-pellets) During the hot-melt stage, the molten material can also be directly cut to produce micro-pellets with a diameter of **0.5 to 3 mm**. These...

Process Analysis Technology am Process Analytical Technology (PAT) Technical Support k? Extruder design and manufacturing technology originating from Germany Support from R&D teams of top domestic universities R* The establishment of a laboratory in Shanghai, open for visits, inspections and testing. To ensure product quality, in addition to standard extrusion process parameters such as melt temperature, melt pressure and specific energy consumption, online monitoring can be applied. Common PAT technologies include Raman spectroscopy, infrared spectroscopy and online NIR detection. Spectra are...