LEICA LMD6 LEICA LMD7 Laser Microdissection Systems

LEICA LASER MICRODISSECTION SYSTEMS Laser Microdissection (LMD) is a technology for precision sample preparation. In many areas of research it is a basic prerequisite for obtaining well-defined starting material for downstream experiments. Meaningful analyses in the fields of genomics, transcriptomics, microarrays, next generation sequencing, biochips, and proteomics are attained using this high-precision technology. The Leica LMD systems perform sample preparation for molecular biology analysis directly from the tissue section using a UV laser. The development of innovative new methods and new...

LEICA LMD6/7 – L ASER MICRODISSECTION SYSTEMS SUPERIOR SOLUTION The Leica LMD process (from top to bottom): Leica Microsystems offers an extremely The Leica LMD6 and 7 employ a very Step 1: Define the region precise, highly selective laser microdis- gentle, laser-based microscopic sample section method for a broad range of manipulation, dissection, and collection superior systems for various applications: › Patented laser beam movement via › Fast, precise isolation of ultra-pure cells and cell populations › High quality dissectates for genomics, transcriptomics, proteomics, meta bolomics, and...

DISSECTION PERFECTION Observe and obtain ultrapure and homogenous samples from heterogeneous starting material - contact- and contamination-free simply by gravity. The Leica LMD6/7 systems make this possible: they combine a fully automated upright high-end research microscope and a UV laser. TWO SYSTEMS, TWO DIFFERENT LASERS Leica offers two freely configurable laser microdissection systems: the Leica LMD6 (Fig. left) and the Leica LMD7 (Fig. right). Both systems are based on a high-end upright research microscope (Leica DM6 B). In addition to the advanced functions of this fully automated research...

LEICA LMD6/7 – L ASER MICRODISSECTION SYSTEMS ADVANTAGES OF LASER MICRODISSECTION Leica Laser Microdissection – simple, intuitive, gentle, and smart sample isolation, collection, and manipulation. › Laser beam movement via optics*: › Specially designed LMD objectives: – Fast, precise, and reliable laser cuts – Ensure the highest possible laser power – Real-time cutting while sample remains fixed – Range of dedicated LMD objectives: 5x, 6.3x, 10x, 20x, 40x, – Convenient documentation by time lapse movies 63x and 150x – 1.25x for fast slide overviews › Specimen collection via gravity: – Simple,...

CONSUMABLES Leica Microsystems offers application specific consumables for laser microdissection with different types of membranes on metal frames, glass slides, and ibidi® and Petri dishes in different sizes. Whether you need slides that have no autofluorescence, use DIC contrast to view the specimen, or need a suitable surface for growing cell cultures – Leica Microsystems has the perfect solution for your application. FOR DISSECTION WE RECOMMEND RANGE OF COLLECTION DEVICES › Leica MembraneSlides: glass slides with PEN or PPS membrane For motorized, scanning and LMT350 stages: › Leica FrameSlides:...

LEICA LMD6/7 – L ASER MICRODISSECTION SYSTEMS STAGES* AND HOLDING DEVICES FOR LMD SYSTEMS The motorized stage HOLDERS Holder for Petri dish Collector with lever Collector with lever with PEN membrane bottom strip tubes (high volume) The scanning stage HOLDERS 11505304 11505311 Holder for 4 slides Adapter la 25 x 76 mm Holder for 3 slides and Petri dish with PEN membrane bottom 11505227 large slides petri dishes 11505312 Universal collector Universal collector Adapter p 11505311for 6x8-strip caps 11505304for 8-strip tubes, tube caps slides and slide stacks tube caps Holder 8-strip caps, Adapter...

UNIQUE LASING WITHIN FLUORESCENCE The ability to perform fluorescence imaging and laser microdissection simultaneously is becoming more important. Lasing within fluorescence using the unique patented axisand filter-system* is one of the strengths of the Leica LMD systems. Whether you are inspecting and dissecting immunolabeled tissue sections or live cells expressing a fluorescent protein – the laser microdissection systems Leica LMD6 and Leica LMD7 make this a standard procedure. In addition, the fully automated fluorescence axis minimizes bleaching effects, accelerates your processes, and offers...

LEICA LMD6/7 - LASER MICRODISSECTION SYSTEMS 9 DEDICATED LASER MICRODISSECTION OBJECTIVES Leica Microsystems offers a portfolio of dry objectives dedicated for Leica LMD systems. These special LMD objectives feature the highest possible UV-transmission and outstanding imaging performance - the Leica SmartCut series (5x-150x). Mag. - magnification; NA - numerical aperture; WD - working distance; BF - brightfield; POL - polarized light; FL - fluorescence; DIC - differential interference contrast; PH - phase contrast; LMD - laser microdissection; CI - cap inspection; SOV - specimen overview; + =...

CAMERA PORTFOLIO Transmitted light, fluorescence or both: Leica LMD systems and software support a range of digital cameras for different requirements. Choose the new Leica LMD CC7000 digital color camera dedicated for LMD applications. The highly compact LMD color camera Leica LMD CC7000 (# 11501478) is a GigE camera with 1/3“ interline progressive scan CCD sensor and 1.2 Megapixel resolution. Experience the speed of the new Leica LMD CC7000, unique for Leica LMD systems. Leica LMD CC7000 digital color camera Choose from the portfolio of Leica microscope cameras Left: Leica LMD6 with one camera:...

LEICA LMD6/7 – L ASER MICRODISSECTION SYSTEMS LIVE CELL CUTTING ACCESSORIES The Leica LMD systems are ideal for any kind of live cell application. With our “sandwich-technology” using membrane rings or our ibidi® slides’ sterile micro hambers*, c live cells are easily dissected in a sterile environment. The LMD system can also be equipped with a climate chamber and full climate control. The time lapse movie function in combination with the laser beam movement by prisms makes it the perfect tool for your laser manipulation experiments. Collect cells or cell clusters via gravity, without any additional...