FOOD TESTING APPLICATIONS eBook ECO Corporation – L company facts C- and GC×GC-TOFMS G instrumentation pecific LECO GC-TOFMS S instrument features eparation Science S product portfolio election of LECO SepSci S App Notes ECO Food Testing L Bibliography Next Page

LECO CORPORATION SOME COMPANY FACTS

SOME COMPANY FACTS LECO CORPORATION Established in 1936 by Carl Schultz, the Laboratory Equipment Company introduced what would be the first rapid carbon determinator to the American iron and steel industry. Today, over 80 years later, LECO continues to be a family-owned company in its third generation of leadership and is recognised globally as a leader in the development of high-quality elemental and thermal analysis equipment, mass spectrometers and chromatographs, metallography and optical equipment, and consumables. Our headquarters in St. Joseph, Michigan, USA, is comprised of several facilities...

Energy & Fuels While LECO has continued to be a leader in carbon/sulfur testing of coal and coke, it has since expanded into biofuels, biomass, oil additives, petroleum products. Ensuring existing sources, and analysing fuels of the future – LECO technology is here to validate their potential and quality. Environment & Agriculture LECO instruments helps to monitor environmental impact, manage agricultural resources more efficiently by monitoring composition of arable soils, crop and fertilisers; determining optimum nutrition values for animal feed. Food Safety Multi residue methods and screening...

BENEFITS OF GC×GC Comprehensive two-dimensional gas chromatography (GC×GC) is an analytical technique that has been around for over 25 years. GC×GC increases separation capacity by using two separate columns with orthogonal selectivity connected in series through a modulator (Figure 1). The modulator rapidly traps and "injects" the effluent from the first dimension column onto the second dimension. Figure 1: Principle of GC×GC The result of a GC×GC analysis is a chromatographic plane (contour plot) (Figure 2), that depicts the separation over the nonpolar and polar columns. The chromatographic...

BENEFITS OF TIME-OF-FLIGHT MASS SPECTROMETRY A time-of-ight mass spectrometer (TOFMS) for gas chromatography (GC) (Figure 3) is the right choice for complex samples, targeted and non-targeted analysis and fast GC or GC×GC. Time-of-flight mass spectrometry (TOF-MS) is probably the simplest method of mass measurement to conceptualise. The ion’s mass-to-charge ratio is determined via a time measurement (Figure). The ability to collect a full mass range without sacricing data acquisition speed or sensitivity is perfectly suited for non-targeted analyses. Using a non-targeted approach is benecial...

SPECIFIC LECO GC-TOFMS INSTRUMENT FEATURES

STAY CLEAN® ION SOURCE STABILITY Fouled ion sources and related issues are often time consuming to diagnosis and resolve. A definitive diagnosis can only be achieved after other preventative maintenance steps (inlet maintenance, column trimming, etc.) have been tried and tested. Once the source has been pinpointed as the issue, users have to clean the source before proceeding. Even routine, scheduled preventative cleaning leads to system downtime In less controlled environments the incremental contamination of an ion source may not be noticed until long past the point of compromised results or...

LECO MULTI-MODE SOURCE ™ IONIZATION SOURCE FOR GAS CHROMATOGRAPHY MASS SPECTROMETRY The innovative Multi-Mode Source™ (MMS™) takes all of the advantages of the three most common ionization modes – Electron Ionization (EI), Positive Chemical Ionization (PCI), and Negative Chemical Ionization (NCI/ECNI) – and combines them into one easy-to-use source. No more hardware switching, no more alignment issues: with the MMS, changing ionization modes is as easy as a click of a button. The new MMS has great mass accuracy and high resolution on pseudo-molecular ions, which complements the traditional Electron...

LECO MODULATOR PORTFOLIO GC×GC offers dramatic improvements over traditional GC for the analysis of complex mixtures. This is due to significantly increased chromatographic resolution. The modulator, considered the heart of the GC×GC system, is a device which injects the effluent from the primary column to the secondary column. There are two primary forms of modulators in GC×GC; thermal- and flow-based. These techniques are described in general terms, but with focus on flow modulation. Thermal-based modulators (Figure 6) rely on a cooling mechanism to trap eluent from the first column, followed...

LECO ChromaTOF ® SOFTWARE LECO‘s ChromaTOF software is uniquely designed to process and analyse the large amounts of data that are acquired with our time-of-flight instruments. ChromaTOF offers seamless control of both the instrument and its accessories, as well as an intuitive interface with highly integrated data processing. ChromaTOF is the first mass spectrometry data system to fully accommodate multidimensional chromatographic data (GC×GC). Benefits of LECO ChromaTOF • Single software platform • Automatic tuning within user-defined Quality Control methods • Intuitive Acquisition Method Setup...

LECO ChromaTOF ® TILE ANALYTICAL SOFTWARE The volume of GC×GC data can quickly become overwhelming. Multiple tables of thousands of analytes can require months of data mining at a pixel level to find the minute differences between data sets, and even those results are plagued with false positives from normal chromatographic variation. ChromaTOF Tile is an enabling technology that has reduced our peak picking time from 10 days to 10 minutes. We are now comparing groups of peak-rich samples from complex studies that would have previously required complicated, custom-built solutions. Benefits of...

SEPARATION SCIENCE PRODUCT PORTFOLIO