Why LAMBDA replaced the traditional rotational stirring with a unique and efficient agitation? Advantages of LAMBDA's non-rotational agitation Quality sealing allows to maintain sterility easily for long continuous runs Effective & economical sealing No complex head-plates & baffles Saves money, simplifies the setting up process and reduces cleaning time Efficien t mixing for all types of cultu re : bacte rial, mammal ian & fungal cells Cells are not des troyed due to shear stress Increased cell viability with optimal bio-mimicking "fish-tail" ag itation Optimal oxygen transfer (OT R) without air flood ing Induces hydrodynam ic shear stress to cells Destructive effect on culture growth Unreliable seal s to close the moving immobile vessel ~ High risk of contamination Increased handling complexity, downtime, foaming and complex internal environment Vortex controlling baffles compl icate the set-up & clean ing process Inefficient gas & mass transfer in the media