MINI-4-Gas, the automatic gas-mixing module - Leaflet

Product catalog summary

Overview: The LAMBDA MINIFOR Bioreactor & Fermentor accessories include the MINI-4-GAS module, designed for automatic gas mixing in bioreactors and fermenters. It supports various applications such as stem cell and mammalian cell culturing, anaerobic fermentation, and microbial systems.

Specifications: The MINI-4-GAS module allows for the mixing of up to four gases, including oxygen (O2), carbon dioxide (CO2), nitrogen (N2), and optionally methane or carbon monoxide. It features MASSFLOW gas flow controllers with flow rates ranging from 0-5 L/min to 0-500 ml/min. The system is controlled via the SIAM software extension, which provides process control, data storage, and visualization.

Procedures: The module supports various fermentation processes such as batch, fed-batch, continuous, chemostat, and perfusion. It offers both submerged and headspace gassing options, with flow rates up to 5 L/min and 20 L/min, respectively. The system is designed for easy setup and integration, with out-of-the-box start-up capabilities.

Norms and Standards: The system is equipped with RS-232/RS-485 interfaces for connectivity and does not require additional software licenses for expanding the number of connected units. It is compatible with a range of laboratory instruments and supports remote control and data acquisition.

Recommendations: The MINI-4-GAS module is recommended for laboratories focused on R&D and process optimization, particularly in the fields of stem cell and mammalian cell culture. It is designed to maintain optimal physiological conditions, prevent stress, and enhance product yield and cell line stability.

Key Features: The system includes individual PID controllers for each gas, real-time trend graphs, and easy set-point adjustments. It is user-friendly, durable, and reliable, with options for stand-alone or remote-controlled operation.

Conclusion: The LAMBDA MINIFOR with the MINI-4-GAS module provides a comprehensive solution for controlled gas mixing in bioreactors, enhancing the efficiency and reproducibility of cell culture processes.

Catalog excerpts

MINI-4-Gas, the automatic gas-mixing module - Leaflet-1

The LAMBDA MINIFOR Bioreactor & Fermentor accessories: MINI-4-GAS • 4-gas-mix for stem cell & mammalian cell culturing • O2-enrichment for microbial systems & biofuel development MINI-4-GAS The automatic gas-mixing module 4-Gas-mixing module for bioreactors and fermenters

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MINI-4-Gas, the automatic gas-mixing module - Leaflet-2

The LAMBDA MINIFOR Bioreactor & Fermentor accessories: MINI-4-GAS MINI-4-GAS: The automatic gas-mixing What is it about? The MINIFOR bioreactor and fermentor system is used for growing and testing bacteria, yeast, fungi, mammalian cells and stem cells. MINI-4-GAS is a module for MINIFOR that allows fully automatic gas-mix. The MINI-4-GAS consists of MASSFLOWs and PC-Software. A MASSFLOWS is measuring and regulating the gas-flow of the gas. It is controlled by the SIAM software extension. The LAMBDA gas-mixing module allows a flexible mass flow controlled supply of different gases with individual...

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MINI-4-Gas, the automatic gas-mixing module - Leaflet-3

The LAMBDA MINIFOR Bioreactor & Fermentor accessories: MINI-4-GAS MINIFOR bioreactor SIAM PC-software * Handles up to 4 bioreactor units with their individual 4-gas controllers. * Free selection of gas types: Air, Oxygen, Carbon dioxide, Nitrogen for high precison; (optional: Methane, Carbon monoxide, ...) Process control PC-software; Preconfigured & Installed on Laptop or Notebook; Data storage & Plotting; Data acquisition, calculations & gas transfer rates; trend graphs display; extended visualization. Individual flow rates per gas: * Submerge (up to 5L/min) * Headspace (up to 20 L/min) Out-of-the-box...

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MINI-4-Gas, the automatic gas-mixing module - Leaflet-4

The LAMBDA MINIFOR Bioreactor & Fermentor accessories: MINI-4-GAS LAMBDA MASSFLOW Which gases do your cells need? Example 4-GAS Mixing for mammalian cells: Build now your own automatic gas-mixing module! The MINI-4-GAS is as easy to interlock as plastic bricks: MINI-4-GAS is modular. According your project, you can choose: The amount of gases The type of MASSFLOW for each gas (0 – 5 L/min or 0 – 500 ml/min flow range) The bricks of MINI-4-GAS are LAMBDA MASSFLOWS. Each MASSFLOW will control one gas in your gas-mixture. You can choose two, three or four gases for your gas-mix. The MASSFLOWS will...

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MINI-4-Gas, the automatic gas-mixing module - Leaflet-5

The LAMBDA MINIFOR Bioreactor & Fermentor accessories: MINI-4-GAS The PC-Software The SIAM extension Out-of-the-box start-up! The SIAM PC-software is an automation software for laboratories in biotechnology and chemistry. Real-time trend graphs Vizualization of the entire process & data storage. SIAM allows the remote control and data storage during cell growth, production phase of fermentation, biotrasformation and other processes in bioreactors and fermentors. Individual PID controller for each gas The MINI-4-GAS is a SIAM software extension for automatic gas-mixing. Easy set-point adjustment...

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MINI-4-Gas, the automatic gas-mixing module - Leaflet-6

The LAMBDA MINIFOR Bioreactor & Fermentor accessories: MINI-4-GAS LAMBDA advantages Compared to most biotransformations with quick growing yeast or bacteria, mammalian cell cultures by their low specific growth rates have to be cultured for weeks or even months for satisfying the product yields. Maintains optimal physiologic culture conditions Optimized process efficiency Retain reproducible production Preclude limiting conditions Prevent inducing physical & chemical stress Increase titer / product yield Satisfy the cells requirement Cell line stability Grow high-density cultures Optimized substrate...

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MINI-4-Gas, the automatic gas-mixing module - Leaflet-7

The LAMBDA MINIFOR Bioreactor & Fermentor accessories: MINI-4-GAS Set-up your own gas-mixing station LAMBDA Item N° 800012 800013 Item Description Additional regulated gas flow LAMBDA MASSFLOW 0-5 l/min) Additional regulated gas flow LAMBDA MASSFLOW 0-500 ml/min) PUMP-FLOW INTEGRATOR for Massflow LAMBDA CZ s.r.o. Lozibky 1 CZ-61400 Brno CZECH REPUBLIC – EUROPE Remote control cable for LAMBDA pumps (8 poles) Quadruple plug box (power and RS-connection for up to 4 LAMBDA laboratory instruments) SIAM industrial automation software Gas controller software module PC connection kit with RS 485 to RS...

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