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Test Method for Water Vapor Permeability Performance of the Medical Hydrogel

Test Method for Water Vapor Permeability Performance of the Medical Hydrogel
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Test Method for Water Vapor Permeability Performance of the Medical Hydrogel - 1

Test Method for Water Vapor Permeability Performance of the Medical Hydrogel Abstract: The primary application of hydrogel in the medical field is the wound dressing. As the closest biological functional material to living tissues, hydrogel can make direct contact with human tissues, prevent external microbial infection, effectively prevent the loss of body fluids, and transmit oxygen and promote wound healing. At the same time, as a drug release carrier, because of its good permeability to low molecular solutes, it also gives the function of hydrogel drug transport system. In this paper, the principle of cup method is used to test the water vapor transmission rate of hydrogel, and introduces the test principle, the parameters and applicable scope, the test process and other contents of W3/062 Water Vapor Transmission Rate Test System, which can be used for reference by enterprises and related institutions in testing the water vapor permeability performance of similar medical hydrogel products. Keywords: wound dressing, hydrogel, water vapor permeability, moisture resistance performance, water vapor transmission rate, water vapor transmission rate test system, cup method, weighing method, inverted-cup method As an organ covering the surface of the human body, the skin is vulnerable to a variety of external injuries. The large area skin defect is difficult to repair due to the difficulty of skin in the defect area, the recovery period is long and the operation itself would bring injury. Therefore, the treatment would be difficult. Medical hydrogel contains a large amount of water (up to 90%), which has soft texture. Its physical properties are similar to biological tissue with excellent biocompatibility, and adjustable mechanical properties. Therefore, it is an excellent biological material. Hydrogel has a good effect on the traumatic surface. Hydrogel on the wound surface can prevent wound infection and promote wound healing, conducive to the early wound recovery.

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Test Method for Water Vapor Permeability Performance of the Medical Hydrogel - 2

Common medical hydrogel is semi-permeable, which has the effect of blocking bacteria, preventing wound infection, and allowing oxygen and water to pass through. Therefore, the water vapor performance of the hydrogel is very important, which is related to the recovery process of the injured. This paper introduces a test method for the water vapor permeability performance of medical hydrogel. Figure 1. Common Medical Hydrogel 2. Test Sample A certain hydrogel was used as the test sample. 3. Test basis This paper evaluates the water vapor transmission rate of a sample by testing the water...

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Test Method for Water Vapor Permeability Performance of the Medical Hydrogel - 3

Figure 2. W3/062 Water Vapor Transmission Rate Test System 4.1 Test Principle W3/062 works according to the test principle of the water vapor permeable cup weighing method, a specific humidity difference is formed on both sides of the sample at a certain temperature, and the water vapor passes into the dry side through the sample in the permeable cup. By measuring the change of the weight of the permeable cup over time, the water vapor transmission rate and other parameters of the sample is obtained. The test cell is the dry side for the weight reduction method and the wet side for the...

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Test Method for Water Vapor Permeability Performance of the Medical Hydrogel - 4

10% RH ~ 98% RH, humidity control accuracy is ±1%RH;  The purge flow speed is 0.5 ~ 2.5 m/s, which can ensure the constant humidity difference inside and outside the permeable cup; Two fast calibration methods of reference film and standard weight to ensure the accuracy and versatility of the detection data; The system adopts the cylinder lifting mechanical structure design and intermittent weighing measurement method, which effectively reduces the system error; Compatible to LystemTM Laboratory Data Management System to manage in an unified way of test results and test reports; 4.3 Scope...

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Test Method for Water Vapor Permeability Performance of the Medical Hydrogel - 5

(1) Cut out 6 uniform and intact samples. (2) Add a certain amount of distilled water to the permeable cup, put the sample, and then clamp the permeable cup cover to ensure that the permeable cup and the sample is well sealed without leakage. (3) Put the permeable cup on its holder of the equipment, close the test cell door, set the sample name, test temperature, humidity, test mode and other parameter information on the control software, click Test button, and conduct the test according to the set parameters. (4) After the test, the computer software shows the test process curve and the...

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Test Method for Water Vapor Permeability Performance of the Medical Hydrogel - 6

Water vapor permeability is an important performance of medical hydrogel and has an important influence on the healing of wound sites. In This paper’s test, hydrogel samples was tested on W3/062 Water Vapor Transmission Rate. The test process is simple and the equipment is easy to operate with accurate temperature and humidity control and high test efficiency compared with the traditional oven control and weighing, the test method has automatic timing, automatic weighing, higher intelligence, less human interference. Moreover, the permeation and weighing are carried out in the same...

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