SAFE Sens® pH monitoring Continuous pH monitoring of media during embryo culture within large format incubators Advantages of the SAFE Sens® pH monitoring system: • Independent, non-invasive monitoring of pH-value throughout the entire embryo cultivation • Real time data of the pH-value every minute or every 30 minutes for up to 7 days • Accurate measurements: ± 0.05 in a range of pH 7.00 to 7.60 • Monitoring of up to 8 chambers or incubators with one TrakStation™ • Installation in < 10 minutes • Intuitive and easy to use; easy to install by user Email: [email protected] Address: Labotect Labor-Technik-Gottingen GmbH Kampweg 12 37124 Rosdorf Germany Postal address: Labotect Labor-Technik-Gottingen GmbH Postfach 200212 37087 Gottingen Germany Court of register: Gottingen: HRB 1394 WEEE-Reg-No: DE 86039820 Managing director: Delia Schinkel-Fleitmann Dr. Friederike Fleitmann

Product features: • SAFE Sens® measurement technology utilizes a patented and proven LED-based optical fluorescent system • Included software for data recording capabilities and automatic alerts by e-mail • Monitoring without staff intervention and door opening • No petri-dish used (non-invasive) • No costly, time consuming calibration required: • One qc2 alignment tool needed per laboratory • Automatically adjusts fluorescent signal to restore to factory settings • No outside calibration services required, no incubator down time SAFE Sens® TrakStation™ SAFE Sens® TrakPod™ SAFE Sens® sterile...