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PLATINblue brochure

PLATINblue brochure
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PLATINblue brochure

Product catalog summary
Overview: The PLATINblue UHPLC/HPLC Plus systems are advanced liquid chromatography solutions designed to enhance laboratory productivity with high resolution, throughput, and flexibility. They are available in two main versions: UHPLC for ultimate performance and HPLC Plus for routine applications.
Specifications:
  • PLATINblue UHPLC: Operates up to 1000 bar with flow rates up to 2 ml/min, suitable for high sensitivity and MS applications.
  • PLATINblue HPLC Plus: Supports up to 750 bar, upgradeable to UHPLC, offering a cost-effective solution.
Features:
  • Modular system architecture with integrated degasser and optimized system volume.
  • High-speed autosampler and fast detectors with up to 100 Hz data rate.
  • Gradient flexibility with binary high-pressure and quaternary low-pressure options.
  • Comprehensive software support including ChromGate®, EZChrom Elite, and Chromeleon®.
Performance:
  • High resolution and throughput with fast separations and optimized communication for short cycle times.
  • Capability to process up to 768 samples in well plates or 96 samples in standard vials.
  • Fast detection with high data acquisition rates for accurate integration.
Precision and Sensitivity:
  • Low pulsation eluent flow and stable baseline with electronically controlled pump drive.
  • High light intensity and optimized flow cells for sensitive detection.
  • Excellent reproducibility with advanced column thermostat and low noise specifications.
Ease of Use:
  • Intuitive touchscreen control and automatic configuration for ease of operation.
  • Reliable and GLP compliant with features like automatic pump head detection and comprehensive reporting functions.
  • Easy maintenance with accessible system components and simple lamp replacement.
Components:
  • High-pressure pumps for both UHPLC and HPLC Plus with SmartMix mixing technology.
  • Diode Array Detector with high sensitivity and fast data acquisition.
  • Fluorescence Detector suitable for trace-level analysis with high acquisition speed.
Software and Scalability:
  • ChromGate® PLATINblue Edition offers user-friendly, scalable, and compliant software solutions.
  • Supports FDA 21 CFR Part 11 compliance and provides flexible reporting functions.
Conclusion: The PLATINblue systems provide a versatile and efficient solution for liquid chromatography, offering high performance, ease of use, and adaptability to various laboratory needs.
Ionization Techniques: Electrospray Ionization (ESI) is suitable for polar compounds or ionic substances, while Atmospheric Pressure Chemical Ionization (APCI) is suitable for hydrocarbons, alcohols, aldehydes, ketones, and esters.
System Integration and Performance: The PLATINblue UHPLC system integrates with Xcalibur™ for complete LC instrument control and mass spectrometer data handling, supporting splitless sample introduction and fast scan speeds.
Ease of Use: The MSQ Plus™ detector is robust and easy to handle, with quick probe exchanges and tool-free maintenance.
Application Areas:
  • Pharmaceutical: Separation of paracetamol and synthesis impurities, steroids, and Sudan dyes.
  • Bioanalytical: Separation of nucleosides and bases.
  • Environmental: Determination of pesticides and EPA PAH.
  • Food: Quick determination of tocopherols and water-soluble vitamins.
  • Clinical: Determination of sedatives and separation of tt-muconic acid in urine.
Column Product Lines: KNAUER offers BlueShell, BlueOrchid, and Bluespher columns designed for ultra high-performance liquid chromatography applications.
Support and Warranty: KNAUER provides comprehensive support and maintenance programs, including a three-year warranty with a service agreement, installation, training, and method development assistance.
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Catalog excerpts

PLATINblue brochure-1

UHPLC/HPLC Plus systems ► What limits your LC today?

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PLATINblue brochure-2

Flexibility More than just UHPLC Optimized Eluent supply Eluent mixing Injection Column Detection Data processing The PLATINblue family of liquid chromatography instruments was designed to offer superior results not only in terms of resolution and throughput, but also in terms of reliability, operating costs, and ease-of-use. PLATINblue systems are capable of running under standard HPLC conditions, fast LC conditions, and UHPLC up to 1000 bar. Freedom of choice Depending on your lab‘s current application focus we offer two versions of PLATINblue premium liquid chromatography systems: 2 PLATINblue...

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PLATINblue brochure-3

Productivity High resolution and throughput Increase your laboratory’s productivity with PLATINblue UHPLC/HPLC Plus and achieve: 2 higher resolution and unmatched separation efciency at equivalent column lengths 2 faster separations, thanks to the use of shorter columns with equal or higher separation performance Comparison of UHPLC, HPLC Plus and HPLC High resolution 2 PLATINblue UHPLC offers ultimate performance with an extended pressure range up to 1000 bar (15000 psi) at flow rates of up to 2 ml/min and of 800 bar (11600 psi) up to 5 ml/min 2 Optimized system volume Short cycle time 2 fast...

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PLATINblue brochure-4

Excellent reproducibility of overall system 80 70 60 50 mAU High-quality PLATINblue components were designed to work together perfectly to enable accurate measurement with optimal reproducibility – a prerequisite for analysis results you can rely on. The sharp and narrow peaks produced by fast chromatography in conjunction with low-noise and low-drift PDA detectors ensure sensitive measurements. Ultimate detection sensitivity 2 electronically controlled pump drive provides for low pulsation eluent flow and a stable baseline Precision can only be as good as the weakest link in the chain. All critical...

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PLATINblue brochure-5

Ease of use Simple to operate and to service Tip The lifespan of the detector lamps can be conserved by having one or both turned off during interruptions in analysis and switched back on automatically when resuming measurements. 2 intuitive touchscreen control* Easy access for quick maintenance 2 automatic conguration of communication with PC and software eases setup 2 solid glass doors provide convenient access to system components 2 automatic selection of optimal detector integration time To stay focused on what is really important, the PLATINblue ultra high-performance LC system is equipped...

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PLATINblue brochure-6

PLATINblue Component overview 2 PLATINblue UHPLC HPG Pump: P-1/P-1 Ultra high pressure pump optimized for fast liquid chromatography, capable of pressures up to 1000 bar (15000 psi) and flow rates up to 5 ml/min. The electronically controlled pump drive provides for low pulsation, a highly precise flow rate and a stable baseline. Flow rate 0.01 – 5.0 ml/min or 0.001 ml increments Flow rate accuray ±1% Flow rate precision < 0.1 % Pressure range UHPLC: 1000 bar up to 2 ml/min, 800 bar up to 5 ml/min Eluent mixing SmartMix UHPLC mixing technology binary HPG: 2 x Pump P-1, integrated 2 channel degasser...

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PLATINblue brochure-7

The column thermostat PLATINblue T-1 is also available without switching valves. User-friendly, scalable and compliant ChromGate® PLATINblue Edition is our easy-to-use software solution for laboratories with high demands for functionality, flexibility and scalability, as well as GLP compliance. Based on EZChrom Elite™ software, ChromGate® PLATINblue Edition software adds extended KNAUER-specific functions. Smart product features that save time 2 PLATINblue AS-1 Autosampler TInject samples from well plates and standard vials accurately and fast with this UHPLC autosampler, which can handle pressures...

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PLATINblue brochure-8

Ultimate Front-end for LC/MS PLATINblue UHPLC in combination with the MSQ Plus™ mass spectrometer offers the most sensitive and compact LC/MS solution for high throughput applications. Seamless integration Versatile 2 when operating the PLATINblue UHPLC system as part of an LC/ MS solution, Xcalibur™ takes over complete LC instrument control and mass spectrometer data handling 2 splitless sample introduction at flow rates up to 2 ml/min for maximum transfer of analytes High performance 2 highly sensitive ion optics 2 60° M-Path™ source for high ruggedness and lowest carryover 2 square quadrupole...

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PLATINblue brochure-9

PLATINblue systems can be flexibly used to increase the throughput and sensitivity of many applications. Benefit from the advantages of highspeed UHPLC applications without having to completely convert your established HPLC methods. The following are only a few examples of the applications possible with PLATINblue. Wide range of application areas Pharmaceutical Separation of paracetamol and common synthesis impurities Separation of Sudan dyes Separation of nucleosides and bases Separation column BlueOrchid C18 1.8 µm, 100 x 2 mm Separation column BlueOrchid C18 1.8 µm, 50 x 2 mm Separation column...

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PLATINblue brochure-10

Efficiency KNAUER UHPLC columns Food Quick determination of tocopherols Determination of water soluble vitamins Separation of Sudan dyes Determination of sedatives, e.g. barbiturates KNAUER offers three different column product lines, specifically designed for ultra high-performance liquid chromatography applications. Separation of tt-muconic acid in urine (I) BlueShell ®columns Separation column BlueOrchid Si 1.8 µm, 50 x 2 mm Separation column BlueOrchid C18 A 1.8 µm, 100 x 2 mm Separation column BlueOrchid C18 1.8 µm, 50 x 2 mm Separation column BlueOrchid C18 1.8 µm, 50 x 2 mm Separation...

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PLATINblue brochure-11

Support Fast and reliable Service Service WarrYear anty WarrYear anty Installation Installation & Training & Training WarrYear WarrYear anty anty We offer you a three-year warranty on every PLATINblue system in conjunction with a service agreement. This entitles you to an all-inclusive full service plan. The reliable and continuous operation of your PLATINblue system is our highest priority. Cons Con Conssu ulting lting To keep all of the components in your PLATINblue system running with the highest performance, we offer a comprehensive support and maintenance program to ensure your system’s...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.