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Freezing point osmometry

Freezing point osmometry

Freezing point osmometry

Product catalog summary
Overview: The document provides detailed information about the KNAUER K-7400S Semi-Micro Osmometer, a device used for measuring the osmolality of solutions through freezing point depression. It highlights the device's features, technical specifications, applications, and the theory behind osmolality measurement.
Theory of Osmolality: Osmolality measures the concentration of particles in a solution, independent of their nature. It is determined by the number of osmotically active particles, not their chemical properties. The document explains that solutions with the same number of particles exhibit the same osmolality.
Measurement Process: The K-7400S uses a microprocessor-controlled Peltier element to cool the sample, initiating freezing through a stirring wire. The temperature is measured with high precision, allowing for accurate determination of the freezing point and, consequently, the osmolality.
Technical Specifications: The osmometer features a sample volume range of 50-150 µl, an osmolality range of 0-2000 mOsmol/kg, and a resolution of 1 mOsmol/kg. It offers a test time of approximately 2 minutes and precision with a standard deviation of ≤ 4 mOsmol/kg for lower ranges and a relative standard deviation of ≤ 1% for higher ranges. The device includes an RS-232 interface for connectivity and can be controlled via a keypad or optional software.
Applications: The K-7400S is suitable for various fields, including pharmaceuticals, food, industry, and academia. It is used for quality control of infusion solutions, isotonic drinks, and other solutions where osmolality is critical. The document provides examples of analyses conducted on isotonic drinks and infusion solutions, demonstrating the device's utility in ensuring product specifications and patient safety.
Software and Data Management: The EuroOsmo 7400 software enhances the device's functionality by allowing data management, visualization of measurements, and integration with laboratory information systems. It supports various operating systems and facilitates sample identification through barcode scanning.
Ordering Information: The document lists product numbers for the osmometer and its accessories, including calibration solutions and sample tubes. It emphasizes the importance of using compatible sample tubes to ensure accurate results.
Conclusion: The KNAUER K-7400S Semi-Micro Osmometer is a reliable and user-friendly instrument for measuring osmolality, with applications across multiple sectors. Its design and functionality reflect KNAUER's long-standing expertise in osmometry.
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Catalog excerpts

Freezing point osmometry-1

Science Together Freezing point osmometry Made in Germany

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Freezing point osmometry-2

Freezing point osmometry The KNAUER freezing point osmometer The K-7400S Semi-Micro Osmometer can determine the exact freezing point of aqueous solutions. The osmolality of various samples like pharmaceutical solutions or soft drinks can thus be easily determined. Freezing point osmometry The measurement principle of the K-7400S Semi-Micro Osmometer is based on the colligative property of freezing point depression. If a solute is added to a liquid this results in a decreased freezing point of the solution. The depression is 1.858 K per 1 mole of ideally solved compound in one liter of water....

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Freezing point osmometry-3

Freezing point osmometry RS-232 interface Connection for printer or software control. Parking position The four pedestals ensure safe storage of the measuring head while the device is not in use. o Technical data Sample volume 50 - 150 pl Measuring head With the stirring wire and its high-precision thermistor the measuring head is a key component of the osmometer. Osmolality range 0 - 2000 mOsmol/kg Test time ~ 2 min Precision SD < 4 mOsmol/kg [0 - 400 mOsmol/kg], Linearity ± 1.5 % [0 - 2000 mOsmol/kg] o Control via keypad The instrument can be fully controlled via the keypad....

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Freezing point osmometry-4

K-7400S Semi-Micro Osmometer Freezing point osmometry EuroOsmo 7400 control software Additional data management with a user-friendly interface Sample & result list Individual naming of samples and overview of test results. Monitor view Overview of the last measurements to allow quality control of the analysis. Measurement view Visualization of the current measurement. The K-7400S Semi-Micro Osmometer is a standalone device. Therefore, all functions of the instruments are accessible via the keypad. For additional storage and data management functions users can work with the EuroOsmo 7400 software. It...

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Freezing point osmometry-5

Freezing point osmometry 1100 1000 isotonic range = 300 mOsmol/kg ± 10% For process monitoring and quality checks of reagents and chemicals. non-isotonic drinks were analysed using the K-7400S Semi-Micro Osmometer. All beverages advertised to be isotonic, had osmolality values within the range of 300 mOsmol/kg ± 10% (grey bar). Thus, they met the specifications for isotonic drinks defined by the European Food Safety Authority. In contrast, a usual softdrink or an alcoholic beer exhibited much higher osmolalities. Plasma osmolality = 290 ± 10 mOsmol/kg Especially infusion solutions but also solutions...

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Freezing point osmometry-6

Freezing point osmometry Ordering information KNAUER is one of the pioneers in the field of osmometry K-7400S Semi-Micro Osmometer with Measuring head, incl. calibrating solutions (400, 850 mOsmol/kg) and plastic sample tubes Accessories & spare parts In many laboratories, the accurate concentration of solved molecules in a liquid is essential for daily work routine. The KNAUER K-7400S Semi-Micro Osmometer is ideally suited for this task, since most solutes in a liquid can be measured. The determination of total particle concentration or osmolality becomes fast and simple. KNAUER is one of the...

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Freezing point osmometry-7

Dosing, Osmometry Metering, Pumping Detection Technical data or prices are subject to change without All trademarks are the property of their respective owners. notice. Prices may vary by country and do not include Our general terms and conditions apply: taxes, customs duties or delivery. www.knauer.net/terms KNAUER Wissenschaftliche Gerate GmbH Hegauer Weg 38 14163 Berlin, Germany

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.