Biochromatography Bioline

Solid base Bioline Start System KNAUER LC systems for biochromatography use sophisticated instrument and software solutions to achieve high quality separations. The Bioline Start System was designed for the demanding laboratory user, particularly those performing routine analyses in research and development. Thanks to its modular design and full-featured ChromGate® software, the system offers outstanding performance and ease-of-use. The Bioline Start System is resistant to all commonly used buffer solutions because all wetted materials are composed of biocompatible materials. The system can also...

Bioline high resolution columns and rack Bioline high resolution glass columns offer pressure stability up to 100 bar and a thermostatic jacket for temperatures between 0° C and 60° C, making them suitable for a wide range of biochromatography applications. The column hardware design allows for easy exchange of frits and compression of the gel bed up to 120 mm using the integrated adjustable plunger. Moreover, the columns are equipped with an integrated quick release lever and can be closed with just one thread rotation. All column components – including the glass column and flexible and fixed...

The Bioline Rack was designed specifically for Bioline high resolution glass columns but can also accommodate any conventional LC or MPLC columns using rack adapters. Glass columns equipped with a thermostatting jacket can be cooled with a circulating coolant supply integrated into the rack. TIP High resolution BioFox® separation media are available for SEC, IEC, IMAC, and AC. Request separate brochure. Features E flexible assembly of up to 3 Bioline columns, of different or equal size, or other equipment and other columns E central column cooling integrated into the rack E includes drip tray...

Bioline Protein Purification System The Bioline Protein Purification System was designed for routine analyses such as quality control, as well as method development or other tasks requiring more than one separation column. This system is based on the same modular system architecture as the Bioline Start System and offers the same specifications for eluent compatibility and functionality. Flexible automatic column switching and fraction collection are supported. ChromGate® FRC software controls the system and offers advanced fractionation algorithmns for reproducible purification of valuable products....

Large quantities Bioline process chromatography systems Configurations Bioline Process Chromatography Systems offer customizable computer-based upscaling from batch-MPLC up to the kilogram-scale using simulated moving bed (SMB) technology for continuous process purification (eg, 4-zone SMB). For more information, please contact us at [email protected] or call +49 - (0)30 - 80 97 27- 0. E Semipreparative MPLC configurations up to 250 ml/min and up to 500 ml/min for milligram-scale purification E Batch configuration with 1 or 2 pumps for up to a maximum of 2 l/min for 50 cm ID columns E SMB for gram-scale...

High expectations KNAUER analytical systems Tryptic digest of cytochrome C PLATINblue UHPLC/MS system Reliable analytical HPLC systems offering accurate and reproducible measurement results are essential for the monitoring of all bioseparations. KNAUER offers Smartline HPLC for flexible and reliable separations and PLATINblue UHPLC for ultra fast high resolution separations. These systems allow for efficient HPLC or UHPLC analysis of biochemical substances with UV detection or mass spectrometry. As with all of our Bioline systems, both analytical HPLC systems use the same GLP-compliant ChromGate®...

Bioline Start System Flow rate range Max. pressure Detection Wavelength range Noise System control Architecture Conformity 0.05 - 50 ml/min 1 50 bar UV/Vis 190 - 740 nm < 2 x 10-5 AU ChromGate® software 32-bit Client/Server GLP, FDA 21 CFR Part 11 Bioline high resolution columns and rack Column Inner diameter Column lengths Max. pressure Frits Rack capacity Thermostatting borosilicate glass 10, 20, 30 mm 30, 60, 100 cm 100 bar PEEK and PTFE 3 Bioline columns central column cooling integrated into the rack Bioline Protein Purification System Flow rate range Max. pressure Detector A Wavelength...