CONTROL THE PSF CORRECTION AND OPTIMIZATION TEMPORAL STABILITY LONG-TERM IMAGING CONTROL THE AMOUNT OF ASTIGMATISM DEEP IMAGING ADAPTIVE OPTICS ACCESORRY FOR 3D PALM/STORM IMAGING: THE UNPARALLELED ACCURACY AND IMAGING DEPTH A UNIQUE SET OF ADVANTAGES Correct aberrations and restore diffraction-limited PSF. This aberration correction technique delivers the best 2D and 3D localization precision for PALM/STORM imaging. Double the amount of detected photons and improve localization precision. Enables single molecule imaging deep in biological samples. Compatible with 60x and 100x objective lenses and FOVs of most sCMOS cameras. Stable wavefront for >12 hours and dayto-day PSF reproducibility. Optical bypass option available. High optical transmission in the visible wavelength range. Device is also available for infrared spectral range. MicAO adaptive optics software includes aberration detection methods and correction models. Contact us for more details: [email protected] or +33 (0) 1 64 86 15 60

Integrated adaptive optics system for 3D single molecule localization microscopy MicAO 3DSR is the first plug & play adaptive optics device dedicated to 3D single molecule localization microscopy techniques. The quality of the point spread function (PSF) is extremely important in these methods. By correcting aberrations, MicAO 3DSR restores near-diffraction-limited resolution and axial symmetry of the PSF. As a result, the number of detected photons is increased, which in turn improves the localization precision in all three dimensions. Moreover, the deformable mirror inside MicAO 3DSR can introduce...