Harvard Apparatus Physiology Research Catalog
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Harvard Apparatus Physiology Research Catalog - 1

specialized tools & expertise for Animal, Organ & Cell Physiology Regenerative Medicine Precision Pumps Delivery & Sampling Animal Handling Surgical Tools Respiration Behavioral Research Electrophysiology Biosensors Cardiovascular Isolated Organ/Tissue Neuroscience Cell Engineering Cell Biology & Electrophysiology Animal, Organ & Cell Physiology Call to receive other catalogs of interest: Behavioral Research Micro/Nano Fluidics Electroporation & Electrofusion Molecular Sample Preparation

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Harvard Apparatus Physiology Research Catalog - 2

Technical Support, Ordering, Payment, Delivery, Terms & Conditions Domestic Orders Harvard Apparatus 84 October Hill Road Holliston, MA 01746-1388 USA phone Payment Options Purchase Order Terms are net 30 for customers with pre-approved credit. Credit Card Visa, MasterCard, American Express and Discover are accepted. Prepayment To prepay, send check or money order with your purchase order. Call Harvard Apparatus customer service in advance for exact shipping charges or include your UPS or FedEx account number. All checks should be made payable to Harvard Apparatus, in U.S. Dollars and drawn...

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Harvard Apparatus Physiology Research Catalog - 3

regenerative medicine Regenerative Medicine Advancing Regenerative & Tissue Engineering with NEW Systems for... 3D Bioreactors Systems Harvard Apparatus/Hugo Sachs Elektronik has developed new systems to assist the regenerative medicine and tissue engineering researchers in advancing and accelerating 3D bioreactor experimentation. The ORGANIZER™ Series solves the problems of simulating the proper physiological environment to accomplish successful tissue engineering or regenerative organ experiments. Using patented and proprietary technologies Harvard Apparatus has created a biomimic...

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Harvard Apparatus Physiology Research Catalog - 4

regenerative medicine Bioreactor for Hollow Organs, Bronchus, Trachea & Blood Vessels Regenerative Medicine regenerative medicine holder induce continuous mixing of the culture medium to increase oxygenation and mass transport. The cell/matrix construct is moved by a DC motor (0-5 rpm adjustable) separated from the culture compartments. The connection between the motion unit and the culture chamber allows the first to remain in the incubator for the whole culture period, moving the chamber independently every time is needed (i.e. sampling, medium exchange). An external control unit...

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Harvard Apparatus Physiology Research Catalog - 5

NEW 3D Bioreactor Systems (continued) Zoro BJH et al. (2009) Regenerative medicine bioprocessing: Concentration and behavior of adherent cell suspensions and pastes. Biotechnology and Bioengineering. 103(6): 1236-1247 3-D Bio-Reactor System from Hugo Sachs Elektronik/Harvard Apparatus GmbH PHD 2000 Syringe Pump from Harvard Apparatus Bedirli A et al. (2005) Effects of Ischemic Preconditioning on Regenerative Capacity of Hepatocyte in the Ischemically Damaged Rat Livers. Journal of Surgical Research.125(1): 42-48 Jin LH et al. (2009) Substantial detrusor overactivity in conscious...

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Harvard Apparatus Physiology Research Catalog - 6

isolated heart Whole Heart Decellularization/Recellularization Chamber for Regenerative Medicine Regenerative Medicine isolated heart Langendorff & Working Heart Perfusion Ssytem Langendorff Benefits & Features • Low flow resistance and dead space volume, minimize perfusion artefacts • Compact, does not require high water columns, suitable for hearts from hypertensive animals (perfusion pressure up to 300 mmHg is possible) • Constant pressure or constant flow in one unit • Drug injection pathway built directly into aortic perfusate stream • Modular system grows with your application •...

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Harvard Apparatus Physiology Research Catalog - 7

isolated heart Whole Heart Decellularization/Recellularization Chamber for Regenerative Medicine (continued) The functional principle of the IH-9 is the same as for the IH-SR and IH-5 The IH-9 is improved for low volume and high environment stability. • Electrodes and stimulator for pacing (see page K70 and section I) All of the components are mounted on the main heart cover chamber, except for the pumps, the oxygenator, the thermostatic circulator and the PLUGSYS amplifier system. Special attention has been made to ensure that all critical connecting tubing are maintained short, thus...

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Harvard Apparatus Physiology Research Catalog - 8

isolated lung Whole Lung Decellularization/Recellularization Chamber for Regenerative Medicine Regenerative Medicine isolated lung Benefits and Features • Optimized temperature conditions for the isolated lung, unique jacketed thoracic chamber • Optional operating table for non-damaging in-situ preparation • Negative-pressure ventilation similar to in-vivo condition or positive pressure ventilation available • Low flow resistance and dead space volume, minimize perfusion artifacts • Unique built-in pneumotachometer and air humidifier with small dead volume • Drug injection pathway built...

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Harvard Apparatus Physiology Research Catalog - 9

isolated lung Whole Lung Decellularization/Recellularization Chamber for Regenerative Medicine (continued) Respiratory Airflow Thoracal Chamber Pressure (intrapleural pressure) Tracheal Pressure Perfusion Pressure Venous Outflow Pressure Lung Weight Changes Lungs can be perfused by either constant flow or constant pressure. Although constant flow perfusion may mimic the in vivo situation more closely, it has the disadvantage that hydrostatic edema becomes inevitable during vasoconstriction. Constant pressure perfusion permits higher perfusate flow rates since vasoconstriction decreases...

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Harvard Apparatus Physiology Research Catalog - 10

syringe pumps The PHD ULTRA™ Nanomite for Cell & Drug Delivery When You Have Limited Samples for Cell Therapy Specifications Regenerative Medicine End-of Run alarm and over pressure alarm Average Linear Force Cable Length English 2 RS-232 serial port, pump may be daisy chained Controller Dimensions, English Controller Dimensions, Metric syringe pumps Cable Length Metric Vacuum fluorescent, 2-line, 40 characters Flow Rate Maximum Flow Rate Minimum Flow Rate Units 4 flow rate units available: nl/hr, nl/min, µl/hr and µl/min BrightBlue™ LED run indicator, Flow Direction arrow on display, will...

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Harvard Apparatus Physiology Research Catalog - 11

The PHD ULTRA™ for Cell & Drug Delivery for Small to Large Fast Bolus Injections for Cell Therapy Flow Rate: Benefits & Features • Inject fast bolus of large or small volumes in • The highest accuracy and precision available • Programmable with multiple methods • Can be controlled by foot pedal or computer • Easy-to-use icon interface • Delivery from picoliterto hundreds of Ml/min PHD ULTRA™ can deliver compositional variations automatically, % mixing of 2 or 3 liquids Concentration mode can automatically adjust the flow to dose animals of different weights with the same % dose. Hundreds of...

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