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A Complete Range of R&D Solutions for Solid Dosage Applications

A Complete Range of R&D Solutions for Solid Dosage Applications
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A Complete Range of R&D Solutions for Solid Dosage Applications - 1

A Complete Range of R&D Solutions for Solid Dosage Applications engineering for a better world

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GEA Group is a global specialist in solid and liquid dose technology. Combining trusted technology with an ongoing programme of innovation and price/performance leadership, GEA has a long history of expertise and an unparalleled depth of experience in the fields of batch and continuous granulation, drying, pelletizing and coating, contained materials handling, tablet compression, pharmaceutical freeze drying, fermentation and liquid formulation, separation, homogenization and cell disruption. With manufacturing and technology centres all over the world, GEA provides the services that the...

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A Complete Range of R&D Solutions for Solid Dosage Applications - 3

Innovate, Partner, Prosper Innovation never stops at GEA It’s what we do! A Complete Range of Technologies for R&D Designed for specific applications, our R&D range GEA believes that by continually covers every aspect of oral solid dosage production, stretching the boundaries of pharmaceutical from high shear mixers, fluid bed dryers and processing, we can help our customers to enhance single pot systems to extruders and spheronizers, the health and well-being of millions of people all over blenders and containment solutions, right through the world. This is what drives our business — and...

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A Complete Range of R&D Solutions for Solid Dosage Applications - 4

At the heart of GEA's small-scale and R&D approach is PharmaConnect™, which allows a number of diverse process modules to be docked to one control unit. Based on GEA's market-leading granulation technologies and designed for laboratory through to pilot plant scale, the PharmaConnect™ can process batches from 200 g to 25 kg or more, all from a single control unit. The PharmaConnect™ is not just limited to granulation; its unique design allows any number of process technologies to be operated from the single operator interface, including • PMA™ - bottom-driven high shear granulation • Gral™ -...

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PMA™ - Bottom-Driven High Shear Granulation Offering a wide range of processing capacities, standard module sizes for the bottom-driven PMA™ are set at 1, 3, 5, 10, 15, 20, 30 and 60 L, with each unit being geometrically scalable. Critically, each of these modules features its own impeller drive motor, maintaining a consistent energy input per unit volume and enabling true scale-up data to be generated, even at the 1 L level, for commercial expansion. % Gral™ - Top-Driven High Shear Granulation The state-of-the-art Gral™ top-driven granulation system is renowned worldwide for its high...

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Contained Processing A complete small-scale production system, from powder to tablet press, the plant includes high shear granulation (PMA™), pelletization, drying, pellet coating (FlexStream™) and blending. Furthermore, by using GEA’s inspired containment technologies, complete solutions can be tailored to suit user-specific requirements, from process integration to loading and discharge via a rigid split valve (BUCK™ MC Valve) or the Hicoflex® disposable bag syst

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High Shear Granulators The GEA high shear mixers and granulators are multipurpose processors that are equally suitable for the high speed dispersion of dry powders, aqueous or solvent granulations, effervescent production and melt pelletization. Process Overview In addition to GEA's modular granulation and blending system (PharmaConnect™), FlexStream™ is an innovative, robust and scalable process technology for spray granulation and pellet coating, delivering unbeatable benefits in terms of productivity and reduced running costs. Containment Valves and Disposable Containment Interfaces GEA...

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For 50 years, GEA has supplied the pharmaceutical industry with advanced solids processing plants for blending, granulating, drying, pelletizing and coating, including small capacity systems for R&D as well as industrial size plants for cGMP-compliant batch production. Based on a long history of experience, thousands of completed tests and with plants installed around the world, we have established a solid base of manufacturing plant and pharmaceutical process expertise. Highlighting the importance of R&D, GEA offers three complementary laboratory scale units, capable of processing batch...

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A Complete Range of R&D Solutions for Solid Dosage Applications - 9

Granulation, Drying, Pelletizing & Coating STREA-1™ Combining versatility with benchtop practicality, the STREA-1™ is one of the most recognisable process machines in the pharmaceutical industry. Specifically designed to process fine powders, pellets, granules, crystals and tablets, the STREA-1™ is the flexible choice when taking the first steps towards process optimisation. Product drying, top spray granulating and coating — from 200 mL to 2 L — are all possible, thanks to its interchangeable components and containers. Continuing GEA’s strong commitment to research and development and high...

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Single-Pot Processing Single- or one-pot technology is the result of integrating mixing, granulation and drying into a single processing vessel. For development purposes, the GEA ultimaPro™ 10 and 25 have batch capacities of 1–9 kg and provide all the key characteristics, granulation and drying options of a production-scale machine; both are compact, mobile and easy to install, oﬀering plug-and-play functionality. The UltimaPro™ combines high-shear granulation with highly efficient vacuum and optional microwave drying technologies, resulting in ultimate flexibility for both pharmaceutical...

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Spray drying is a technique preferred by a growing number of pharmaceutical companies to produce better drugs. This ultrafast and gentle drying technology offers unique ways to define particle characteristics. GEA offers a range of spray dryers designed specifically for R&D, product development and small volume production. A pioneer in all aspects of spray drying with more than 10,000 contracted and installed plants worldwide, we can help you to choose the most suitable equipment, assessing each project on its individual needs and tailor the process and the spray dryer to match your...

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