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Gilson Product Guide

Gilson Product Guide
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Gilson Product Guide

Product catalog summary
Overview: Gilson, Inc. specializes in high-quality solutions for liquid chromatography, solid phase extraction, and gel permeation chromatography, catering to sectors such as pharmaceutical, biotech, environmental, clinical, food, and forensic. Their systems and software enhance laboratory purification processes.
Key Products and Systems:
  • HPLC Systems: Includes GX-281 and GX-271 for preparative and analytical applications, featuring technologies like GX Direct Injection.
  • Liquid Handlers/Injectors: Models like GX-281 and GX-271 offer flexibility and efficiency in sample handling.
  • Pumps: Range from prep-scale to analytical pumps for high-pressure applications.
  • Detectors: Options include diode array, UV/VIS, and evaporative light scattering detectors.
  • Fraction Collectors: Systems like PREPFC™ for efficient sample collection.
Software Solutions: TRILUTION® LC and LH software control HPLC systems and automate liquid handling, ensuring ease of use and reliability.
Innovative Features:
  • VALVEMATE® II Valve Actuator: Offers fast switching times and high-pressure valve control.
  • GX Prep Solvent System: Features syringeless technology for dynamic volume management.
Applications and Markets: Supports drug discovery, environmental analysis, food safety, clinical diagnostics, and forensic investigations.
Specifications: Detailed specifications include reproducibility, flow rate, injection loop volume, and accuracy for various products.
Performance Data: High accuracy and low standard deviation in recovery data for substances like Theophylline and Caffeine.
Additional Features: Ethernet-based communication, dynamic flow rate ranges, and multiple injection modules for high-throughput automation.
Conclusion: Gilson provides robust, flexible, and high-performance solutions for laboratory automation, supporting a wide range of applications.
Specifications and Features: Detailed specifications for liquid handlers, injectors, and detectors, including reproducibility, flow rate, and accuracy.
HPLC Detectors: Includes diode array and UV/VIS detectors with various wavelength ranges and sensitivities.
Fraction Collectors: Designed for various capacities and applications, with features to prevent contamination.
Control Software: TRILUTION® LC and LH software for instrument control, compatible with Microsoft® Windows®.
GPC Clean-up Systems: Designed to meet international guidelines, offering automated and manual options for sample extraction and purification.
Solid Phase Extraction (SPE) Systems: Automate the SPE process with high-throughput applications and positive pressure elution.
Liquid Handlers: Provide versatile solutions for liquid handling tasks with high accuracy and reproducibility.
Key Features: Mobile Rack technology, GX Direct Injection Module, and Positive Pressure elution for enhanced precision.
Flow Cell Selection and Optimization: Charts for selecting appropriate flow cells to optimize sensitivity and peak shape.
Injection Compatibility and Instrument Compatibility: Details on tip shape, material, and required injection ports for specific instruments.
UV Absorbance and Solvent Compatibility: Tables for maximum UV absorbance of solvents and mobile phase conditioners.
pH of Acids and Bases: Lists pH values for chemical compatibility and reaction conditions.
Column Sizes and Capacities: Information on injection volumes, load capacities, and flow rates for chromatographic setup.
Separation Scale-up Equations: Equations for scaling up chromatography processes.
Pressure and Tubing Specifications: Details on pressure ratings and tubing specifications to avoid high back pressure.
Solvent Miscibility and Polarity: Tables to assist in selecting solvents for chromatographic separations.
Temperature and Pressure Conversion: Conversion tables for ease of calculation and system setup.
Liquid Chromatography Techniques: Advanced techniques for flavonoid separation and compound recovery using SPE.
Optimizing Purified Sample Recovery: Factors affecting purity and recovery in preparative HPLC.
Reproducibility in Analytical Systems: Consistent and reproducible chromatography demonstrated by Gilson HPLC systems.
Drug Absorption Screening: Automated system for faster and cost-effective drug permeability screening.
Multi-purpose Preparative System: Uses analytical scout analysis for optimized compound separation.
Effects of Solvents and Techniques: Impact of solvents, injection techniques, and sample amounts on preparative chromatography.
Integrated 2D System: Combines ion-exchange and reversed-phase chromatography for complex mixture separation.
Factors Affecting Recovery: Guidelines for chromatographers on parameters influencing recovery.
Optimized Sample Load Capacity: Smaller preparative columns increase loading capacity and efficiency.
Continuous Injection and Fraction Collection: Method for purifying large sample quantities with continuous injection.
Chiral Separations Optimization: Automated system for enhanced stereoselective screening efficiency.
Automated Liquid Handling: Technical data on the Quad-Z 215 system's accuracy and versatility.
Quality Policy and ISO 9001 Certification: Gilson's commitment to quality through ISO 9001 certification.
Solid Phase Extraction (SPE) Applications: Automated SPE methods for extracting and analyzing compounds, highlighting automation advantages.
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Catalog excerpts

Gilson Product Guide-3

Gilson HPLC Systems Gilson high performance liquid chromatography (HPLC) systems provide complete solutions for all purification needs. Front-end liquid handlers and autosamplers are available in a range of bed capacities and optimized bench space footprints. Several models also accommodate innovative injection and fraction collection capabilities within a single platform. TRILUTION® LC Software completely controls the entire HPLC system, allowing focus to remain on the science rather than the software. The newest innovation from Gilson, the GX-271 Liquid Handler, is a mid-size capacity and throughput...

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Gilson Product Guide-4

HPLC: Systems HPLC System flow rate 1 - 200 mL/min injection loop volume 250 uL - 25 mL sample mass 15 g/injection HPLC System HPLC System HPLC System flow rate 0.15-30 mL/min njection loop volume 2 uL - 2 mL sample mass 300 mg/injection flow rate 1 - 200 mL/min injection loop volume 250 uL - 25 mL sample mass 15 g/injection flow rate 0.15-30 mL/min injection loop volume 2 uL - 5 mL sample mass 300 mg/injection flow rate 1 - 200 mL/min injection loop volume 100 uL - 10 mL sample mass 15 g/injection flow rate 1 - 200 mL/min injection loop volume 5 uL - 25 mL sample mass 15 g/injection flash chromatography...

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Gilson Product Guide-5

GX-281 Analytical to Semi-preparative HPLC System The GX-281 is a multi-functional instrument that can perform injection, fraction collection and reinjection. J The GX Z-lnjection Module allows fast injections with low carryover the sample directly into the valve. Rinse station design that delivers individual streams of solvent for each separate rinse station to actively wash the outside of probes. Four rinse solvents are Separate injection and fraction collection paths reduce cross-contamination of fractions from sample injection. The cycle time of the injection is minimized by eliminating rinse...

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Gilson Product Guide-6

HPLC: Systems The GX-271 is a mid-size liquid handler/fraction collector with a bench saving footprint featuring separate fluid pathways that reduce cross-contamination of samples and fractions. Specifications Sample Loading Capacity 300 mg/injection Injection Loop Volume 2 μL – 5 mL Optimal Column Size 2 – 20 mm Flow Rate H1: 150 μL/min – 15 mL/min H2: 30μL/min – 30 mL/min Maximum Injection Pressure 5,000 psi (345 bar) Gilson’s 845ZPREP™ System features Gilson’s first generation Z-Injection technology accommodating volumes and flow rates for semi-preparative to preparative applications. Maximum...

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Gilson Product Guide-7

HPLC: Liquid Handlers/Injectors Handler Collectio Analytical Liquid Liquid Handling Injection Page Carryover Number Gilson's liquid handlers and injectors offer the broadest range of instrument capabilities on the market today. From small footprint injectors to larger footprint liquid handler/injector/fraction collectors, Gilson provides the ultimate front-end automation solutions for every HPLC system. Specifically engineered for semi-preparative to preparative HPLC requirements, the GX-281 offers unmatched versatility and performance for front-end LC automation including revolutionary syringeless...

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Gilson Product Guide-8

HPLC: Liquid Handlers/Injectors Preparative Liquid HandJer/Jnjector GX-271 Preparative Liquid Handler/Injector The GX-271 Liquid Handler/Injector is the perfect blend of size, performance and capacity, consuming only 23" of linear bench space. Large-bore injection modules feature a continuous flow path design for preparative applications. Small-bore valves are available for analytical to semi-preparative applications with inert injection modules for bio- compatible applications. Recovery data: Theophylline (5 mg/mL), Caffeine (5 mg/mL) and Phenol (3 mg/mL) solution with 1 mL injection loop volumes...

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Gilson Product Guide-9

HPLC: Liquid Handlers/Injectors This versatile, large bed liquid handler accommodates more than 3,000 racks to hold virtually laboratory needs. The 215 Liquid Handler/Injector, a true and trusted laboratory workhorse for manyyears, performs injection, fraction collection and reinjection of collected fractions within a single platform. Product #s: 2510121 (215 Liquid Handler) injection: < 0.9% (1 mL) (total loop) Multiple Probe 215 Liquid Handler/; Inject onto FIA/MS, parallel HPLC and MUX systems using the optional 849 Multiple Injection Module. Product*: 25101311 (Multiple Probe215 Liquid Handler)...

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Gilson Product Guide-10

HPLC: Pumps 333/334 Prep-scale HPLC Pumps Capable of fast separations with high-efficiency columns in normal and reversed-phase modes, Gilson's 333 and 334 Pumps are the premier solvent delivery solutions for preparative chromatography. Choose the 333 master pump for isocratic applications or the 333/334 binary system for composition gradient with high pressure mixing (third pump for ternary). bench space. level mass-throughput depending on column size solvents per pump for a total of eight solvents in a binary pumping system. Flow Rate Gradient Linearity and Accuracy Time (minutes) Retention...

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Gilson Product Guide-11

HPLC: Pumps 3OX Series HPLC Pumps Together with Gilson's manometric modules and dynamic mixers, the 305,306 and 307 Pumps offer a cost-effective, space saving and robust solution for isocratic or gradients of analytical to preparative HPLC. ► The 307 model functions as an isocratic pump with a built-in manometric module. ► Dynamic mixers ensure efficient, dependable gradient creation. Flow Rate slave unit, controlled by either a incorporated keypad. pump head removal, allowing Piston seals, check valves and other parts can be replaced in The 402 Syringe Pumps assure accuracy in sample transfers,...

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Gilson Product Guide-12

HPLC: Detectors Jltraviolet Visible ..[|orf*'V.e ... . t, Spectral . Page (UV) (VIS) L|ghtScat e»"g Wavelength BandWidth Channels Numbgr Diode Array ^ ^ ^ Gilson offers a complete line of HPLC detection solutions that are ideal for analytical, semi-preparative and preparative HPLC applications. Time (minutes) 171/172 Diode Array Detectors Gilson's recently released 171 and 172 Diode Array Detectors deliver rugged and accurate detection for both preparative and analytical HPLC. Detection is done with a fiber optic light path that can be configured in a fixed or remote flow cell design. With remote...

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