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Continuous Manufacturing

Continuous Manufacturing

Continuous Manufacturing

Product catalog summary
Introduction
The document introduces a collaborative solution by Swiss companies Gerteis® and Gericke for continuous tablet manufacturing, combining Gerteis® compacting and granulating technology with Gericke's feeding and mixing solutions.

Approved Systems for Reliable Production
The focus is on adapting the pharmaceutical industry's manufacturing processes to be more efficient, aligning with the Quality by Design (QbD) concept. The technologies from Gerteis® and Gericke are highlighted as ideal for efficient solid dose pharmaceutical manufacturing.

Continuous Feeding and Mixing Technology by Gericke
Gericke's technology offers continuous metering and control of flow rates, chemical composition analysis, and a capacity range from 5kg/h to 500 kg/h. It is designed for precise feeding and mixing, minimizing segregation risks, and is easy to clean.

Continuous Roller Compaction & Dry Granulation by Gerteis®
Gerteis® technology is noted for its low energy compaction capability, minimizing process variability. It offers stable, repeatable processes with significant benefits for scale-up and process stabilization. Product capacities range from 10 grams to 400 kg/h.

Applications and Benefits
The combined technologies are versatile, suitable for various powders, and offer efficiency gains in pharmaceutical manufacturing. Applications include pharmaceuticals, chemicals, foods, and more.

About Gericke and Gerteis®
Gericke provides solutions for conveying, sifting, feeding, and mixing across multiple industries. Gerteis® specializes in high-quality roller compactor dry granulators, leading in dry granulation technology.

Contact Information
Contact details for both companies are provided for further inquiries.
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Catalog excerpts

Continuous Manufacturing-1

Continuous Manufacturing Combined approved technologies swiss made Powder Processing Equipment and Systems

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Continuous Manufacturing-2

Continuous Mixing and Granulation The two Swiss companies Gerteis* and Gericke present the world's first solution for continuous tablet manufacturing. Therefore the Gerteis® compacting and granulating technology is combined with feeding and mixing solutions from Gericke. Both systems are fully developed and have been proven in the market. Approved systems fora reliable production The most important challenge for the pharmaceutical industry is to take the QbD concept and look at its manufacturing processes in 'lean' terms to start to adapt for a more efficient future. Gerteis® dry granulation...

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Continuous Manufacturing-3

Continuous Feeding and Mixing Technology Gericke continuous mixing systems have a capacity from skg/h to 500 kg/h and are used in the pharma industry for: Precise and compact continuous feeding and mixing of API and Minimising risk of segregation Wetting of mixtures upstream wet granulation or fluid bed granu Mixing upstream roller compaction Process Control • Continuous metering and control of flow rates of API and Exciptients • Continuous metering of mixer content and mean mixing time • Chemical composition e.g. by on line NIR spectroscopy Gericke feeders and mixers are designed for quick and...

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Continuous Manufacturing-4

Continuous Roller Compaction & Dry Granulation Gerteis* dry granulation technology is already a continuous technology extensively proven. With the low energy compaction capability it minimises high energy losses likely to generate control and process variability for example caused by temperature variation. Product capacity Mini-Pactor® for development, pilot plant, clinical and small scale production: Macro-Pactor® for development, pilot plant, clinical and full scale production: Best suited for continuous manufacturing Gerteis® advanced roller compaction technology has a numberof control parameters...

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Continuous Manufacturing-5

Natrium bicarbonate Speciality Chemicals Detergent powder Aromas / Flavours Animal feeding Spice extract Instant blends The versatility of the machines from Gerteis and Gericke allows to process virtually all kinds of powder, even the most difficult ones. And with our ingenious machine design, the cleaning cycles are fast and thorough, enabling you to switch between batches swiftly. A wide range of applications are suitable forthis advanced and effici- ent technology combination. The overall efficiency gains in process and true cost of ownership compared to other technologies offer an interesting...

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Continuous Manufacturing-6

Gericke Feeding and Mixing Technologies When space is at a premium, Gericke continuous mixing systems offertine ideal solution. Gericke also provide full recipe management programmes incorporating feeding and flow control for maximum mixing consistency. When the process involves multiple components and frequent product changes, Gericke batch mixing stations are About Gericke Gericke supplies conveying, sifting, high-precision feeding and mixing solutions that handle a broad range of ingredients such as pellets, powders, floodable powders and fibreglass for food, chemi- cal, industrial, and pharmaceutical...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.