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Multiblock VHP

Multiblock VHP

Multiblock VHP

Product catalog summary
Introduction
GEA Niro Soavi is a leader in high-pressure homogenizers, particularly for pharmaceutical and biotech processes. Their VHP (Very High Pressure) Homogenizers are designed for particle size reduction and cell rupture, operating at pressures between 1000 - 1500 bar. The company has also developed an Ultra High Pressure (UHP) homogenizer prototype capable of reaching up to 4000 bar, protected by international patents.

Applications and Advantages
The VHP Homogenizers are effective in cell lysing for bacteria, yeast, algae, and plants, offering higher yields without additional processing steps compared to chemical lysing methods. They are also used for nanoparticle dispersions and emulsions, enhancing product shelf life and minimizing emulsifier use. The technology prevents coagulation and phase separation, improving product quality.

Operating Principle
The homogenization process uses an adjustable valve concept, allowing independent pressure and flow rate settings. The system includes a reciprocating multi-plunger pump and a homogenizing valve, achieving the desired effects through complex fluid dynamics.

Compliance and Specifications
GEA Niro Soavi's equipment complies with FDA and cGMP guidelines, featuring SIP and CIP cleanability. The design ensures compliance with pharmaceutical standards, offering documentation for cGMP validation and ATEX directive compliance for hazardous areas.

Global Presence and Support
GEA Niro Soavi, part of the GEA Group, provides a wide range of products and services globally, supported by ISO 9001:2000 certification. They offer R&D facilities and after-sales service, with a laboratory for testing and developing new applications.

Contact Information
GEA Niro Soavi is headquartered in Parma, Italy, with sales offices worldwide, including in the USA, Brazil, China, and more.
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Catalog excerpts

Multiblock VHP-1

GEA Niro Soavi Very High Pressure Power Technical Leaflet: Multiblock VHP GEA Niro Soavi technologies include VHP Homogenizers which introduced the first UHP (Ultra High Pressure) homogenizer, have become the world standard for particle size reduction and a unique prototype able to reach up to 4000 bar under cell rupture in pharmaceutical and biotech processes. dynamic flow conditions. This UHP technology is covered by The homogenizer used for the treatment is a machine designed for 1000 - 1500 bar whit VHP compression block for high the technological development platform to explore potential new applications and process solutions in food, dairy, chemical, A VHP Homogenizer can be easily scaled-up from the lab and pharmaceutical, biotech and cosmetic industries. pilot systems to commercial size systems. GEA Niro Soavi has engineering for a better world

 Open the catalog to page 1
Multiblock VHP-2

Biotechnology and pharmaceutical applications. Cell Rupture and Particle Size Reduction. Nanoparticles Dispersions and Emulsions. For biologic cell lysing (bacteria, yeast, algae and plants) cells can be successfully disrupted in order to collect the intracellular materials, drastically reducing the production time and costs. In this respect VHP Homogenizer offers distinct advantages over chemical lysing and impinging flow type technologies. Whereas chemical lysing require additional costly purification and recovery process steps to yield the desired product, GEA Niro Soavi VHP technology require...

 Open the catalog to page 2
Multiblock VHP-3

Very high pressure homogenizing technology. Operating Principle. Compliant to Pharmaceutical Specifications. The homogenization technology is based on the adjustable Pharmaceutical and Biotechnology applications require homogenizing valve concept, which allows independent setting specifically designed equipment which must be fully compliant of pressure and flow rate under continuous flow conditions, to with the stringent applicable regulations, such as FDA cover all possible requirements for testing and performance requirements and cGMP Guidelines. scalability. The GEA Niro Soavi VHP homogenizer...

 Open the catalog to page 3
Multiblock VHP-4

Technical Specifications are not mandatory and subject to change without notice. REV 1_04_2012 GEA Niro Soavi in the world. GEA Niro Soavi, part of GEA Group, is the global technology leader in high pressure homogenizers and high pressure pumps for dairy & food, pharmaceutical, chemical and biotechnology industries. It provides leading technology with the widest product range available, R&D facilities and first class after sales service to its business partners. GEA Niro Soavi engineering and manufacturing is certified according to ISO 9001:2000 Quality System to supply homogenizing technology...

 Open the catalog to page 4

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.