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SOLID DOSAGE processing

SOLID DOSAGE processing
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SOLID DOSAGE processing

Product catalog summary
Application Overview
Solid dosage forms, such as tablets and capsules, are prevalent in the pharmaceutical industry. These forms combine active pharmaceutical ingredients (APIs) with binders, fillers, and other excipients to achieve specific characteristics. Processing methods vary based on drug type, dosage form, administration route, and release duration.
Fluid Air, a Division of Spraying Systems
Fluid Air specializes in equipment for solid dosage processing, offering customizable systems like fluid bed dryers, granulators, and process control software. These systems are scalable from research and development (R&D) to production, ensuring consistent performance and batch uniformity.
Fluid Bed Systems
MAGNAFLO and MAGNACOATER systems are customizable for superior performance in solid dosage processing. They feature tapered expansion chambers, agitator rakes, and adjustable shutter plates for precise coating. Available in R&D, pilot, and production scales, these systems maintain critical scale-up factors.
High-Shear Granulators
PHARMX granulators offer customizable mixing systems for homogeneous mixing and efficient granulation. They feature optimized bowl geometry, hydraulic drive systems, and options for one-pot processing. Available in R&D, pilot, and production scales.
Size-Reduction Systems
GRANUMILL systems provide precision particle size reduction and de-agglomeration. They offer variable speed rotors, quick-release housing, and robust rotor designs. Available in R&D, pilot, and production scales.
Electrostatic Spray Dry Systems
PolarDry systems utilize electrostatic technology for efficient encapsulation, reducing evaporation temperature and preventing ingredient degradation. They offer low operating temperatures, nitrogen inerting, and easy clean-up. Available in feasibility, R&D, and pilot scales.
Tablet Coating Systems
These systems provide precise control over coating processes, ensuring uniform application and high-quality results.
Control Options and More
Fluid Air systems offer advanced control options, including data logging and customizable software, to enhance process accuracy and efficiency.
Product Overview
The document provides an overview of various systems and services offered by Fluid Air, focusing on tablet coating optimization and batch processing control. The TABCOATER system is highlighted as a flexible solution for upgrading existing coating equipment, offering both complete systems and individual component upgrades.
Specifications and Features
The TABCOATER system includes a manifold, spray nozzles, a fluid delivery skid, and process controls. Key features include patent-pending internal recirculating guns, anti-bearding nozzles, and customized fluid delivery skids. The Batch Architect process control software is designed for ease of use, offering automation and recipe-based controls, with a Pro version available for 21 CFR Part 11 compliance.
Procedures and Recommendations
The document recommends upgrading existing equipment with new spray technology and process controls to improve performance. It suggests using the Batch Architect software for enhanced control and automation of pharmaceutical processing equipment.
Standards and Compliance
The Batch Architect Pro version supports 21 CFR Part 11 compliance, ensuring electronic batch record data logging and report creation services.
Retrofit Services
Fluid Air offers retrofit services to update existing equipment with modern features such as humidification, solvent recovery systems, and robust control systems. The document emphasizes revitalizing existing equipment without replacement by upgrading components like nozzles and lances.
Conclusion
The document outlines the benefits of upgrading and customizing existing pharmaceutical processing equipment using Fluid Air's systems and services, highlighting the flexibility and compliance features of their offerings.
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Catalog excerpts

SOLID DOSAGE processing-1

SOLID DOSAGE processing page Application Overview Fluid Air, a Division of Spraying Systems High-Shear Granulators Size-Reduction Systems Electrostatic Spray Dry Systems Tablet Coating Systems Control Options and More spray.com | 1.800.95 SPRAY | Intl. 1.630.665.5000

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SOLID DOSAGE processing-2

perfec ting the process In the pharmaceutical industry, a solid dose is a dosage form, such as a tablet or capsule or powder which is ingested orally and generally consists of a mixture of active pharmaceutical ingredients (or APIs, the drugs being delivered) along with a combination of binders, fillers and other excipients designed to imbue the finished drug with specific characteristics. Processing methods for individual pharmaceutical drugs can vary widely depending on the type or types of drugs being manufactured, the dosage form (solid dosage vs. liquid) the intended route of administration,...

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SOLID DOSAGE processing-3

Solid Dosage processing Fluid AIR, A Division of spraying systems co. ® MAGNAFLO® Fluid Bed Systems PHARMX® High-Shear Granulators GRANUMILL® Size Reduction Systems Fluid Air, a division of spraying systems co. ® Fluid Air is a division of Spraying Systems Co. specializing in solid dosage processing equipment for the pharmaceutical industry, including fluid bed dryers/granulators, Wurster coaters, high-shear granulators, size reduction systems and process control software for batch-type equipment. Available in a full range of sizes from R&D to production scale, Fluid Air systems are designed...

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SOLID DOSAGE processing-4

Solid Dosage processing MAGNAFLO & MAGNACOATER Fluid bed systems Product Overview MAGNAFLO fluid bed dryer/granulators and MAGNACOATER Wurster coaters are completely customizable fluid bed systems designed to provide superior performance for solid dosage processing applications from R&D to production scale. Production scale R&D or laboratory-scale units provide effective drying, coating or granulation for small batches. Pilot systems offer a wide range of options for processing larger batches intended for clinical trial or small-scale production. Production scale fluid bed systems for processing...

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SOLID DOSAGE processing-5

Solid Dosage processing Specifications — MAGNAFLO ® & MAGNACOATER ® Fluid Bed systems Extended bowl volume (L) Reduced volume bowls (L) Model Number Standard bowl volume (L) Max. granulating capacity (L) System height (inches/mm) System width (inches/mm) MAGNAlift bin & bowl elevators Product Overview MAGNALIFT bin and bowl elevators elevate, invert, or rotate to blend fluid bed bowls or bins for sanitary discharge into a tablet press, drum, or other process equipment. With options ranging from height, material use, movement, and more, each MAGNALIFT is fully customized to meet your specific...

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SOLID DOSAGE processing-6

Solid Dosage processing Model 0002 Fluid bed system with ultrasonic air atomizing lance Product Overview The Model 0002 fluid bed system for R&D applications is now available with integrated ultrasonic spray technology for superior performance in fluid bed coating, granulation, fluid bed drying and spray drying. Features & BENEFITS – MODEL 0002 fluid bed system • Conidur plates ensure uniform air distribution through the bed • Unique Wurster plate design ensures proper flow of material • Easy-to-use controls, adjustable touch screen and Model 0002 data logging • Spraying Systems Co. nozzles provide...

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SOLID DOSAGE processing-7

Solid Dosage processing Specifications — MAGNAFLO ® & MAGNACOATER ® Fluid Bed systems Ultrasonic bowl volume (L) Ultrasonic bowl volume (mL) System width (inches / mm) Ultrasonic air atomizing lance Nozzle orifice diameter: 0.03" (0.762 mm) Droplet size range: 10-90µm 1/8" NPTF connections (shaping/cooling air inlets and exhaust) 1/2" hygienic liquid inlet connection 316SS lance with titanium ultrasonic horn Choice of FDA VITON or EPDM elastomers Spray Tip: achieve micron-level COATING precision with integrated ultrasonic technology Ultrasonic spray technology delivers the precise, uniform spray...

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SOLID DOSAGE processing-8

Solid Dosage processing High-shear granulators PHARMX High-shear granulators Product Overview PHARMX high-shear granulators are fully customizable bottom-driven mixing systems engineered to provide homogeneous mixing and efficient granulation across a range of available R&D, pilot, and production size models. Production scale R&D or laboratory-scale units provide effective high-shear granulation for small batches. Pilot systems offer a wide range of options for processing larger batches intended for clinical trial or small-scale production. Production scale systems for granulating very large...

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SOLID DOSAGE processing-9

Solid Dosage processing high-shear granulators Specifications — pharmx High-shear granulators Model Number Total bowl volume (L) Charge- max. liters @ light bulk, 0.3 - 0.5 Impeller speed range (RPM) Impeller power (HP) Chopper speed range (RPM) Chopper power (HP) Spray Tip: process hazardous compounds safely with interchangeable bowls For processing potent compounds requiring total containment, we are able to provide customized interchangeable bowls. The bowls can be removed from the console and placed in a glove box / flexible containment structure without any dusting of product from the bowl....

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SOLID DOSAGE processing-10

Solid Dosage processing size reduction systems GRanumill size reduction systems Product Overview GRANUMILL size reduction systems are wet and dry mill systems designed for precision particle size reduction and de-agglomeration applications, available in R&D, pilot, and production scale sizes. Production scale R&D or laboratory-scale units provide effective size reduction or de-agglomeration for small batches. Pilot systems offer a range of options for larger batches intended for clinical trial or small-scale production. Production scale systems for very large batches. Features and Benefits •...

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SOLID DOSAGE processing-11

Solid Dosage processing size reduction systems Specifications — GRanumill size reduction systems System Height (inches/mm) System Width (inches/mm) System Length (inches/mm) Screen Width (inches/mm) Model Number Speed (RPM) Finished particle size mesh (micron) Throughput (lbs/kg)/hour Spray Tip: save time and money with flexible containment enclosures In cooperation with ILC-Dover, we are able to provide custom-designed, flexible containment systems for GRANUMILL Jr. size reduction systems. The Flexible enclosure set-up allows for use in both containment and non-containment applications, eliminating...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.