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PHARMX® HIGH SHEAR GRANULATOR

PHARMX® HIGH SHEAR GRANULATOR

PHARMX® HIGH SHEAR GRANULATOR

Product catalog summary
Overview: The PHARMX® High Shear Granulator is designed for efficient mixing and granulation, optimized for various pharmaceutical processes including R&D, pilot, and production applications. It offers design flexibility to ensure peak performance and can be customized to meet specific processing challenges.
Benefits:
  • Simplifies scale-up processes.
  • Minimizes process downtime.
  • Optimizes production efficiency.
  • Reduces maintenance requirements.
  • Improves product quality.
High-Shear Granulation Process: This process involves turning powders into dense granules suitable for tableting or coating. The powders are mixed in a sealed bowl with a rotating impeller, and liquid is added to form granules. A high-speed chopper shears the granules and removes air, continuing until the desired size and density are achieved. The product can be dried in the bowl or transferred to a fluid bed dryer.
System Features:
  • Optimized bowl geometry allows operation at up to 90% capacity.
  • Equipped with auto-cleaning and liftable tool systems for easy maintenance.
  • Robust variable speed chopper and impeller drive systems for maximum energy transfer.
  • Consistent impeller tip speed ensures effective scale-up.
System Advantages:
  • Flexible bowl configurations to match processing needs.
  • Elliptical vessel lids for homogeneous mixing.
  • Spraying Systems Co. liquid dispersion nozzles for precise liquid addition.
Batch Architect™ Process Control Software: This software maximizes operating flexibility, suitable for both R&D and FDA-compliant applications. It supports manual control or phase/recipe-based control and runs on Allen-Bradley® Logix processors.
Specifications: The document provides detailed specifications for various models, including total bowl volume, impeller speed, and power, as well as chopper speed and power ranges.
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Catalog excerpts

PHARMX® HIGH SHEAR GRANULATOR-1

PHARMX® HIGH SHEAR GRANULATOR EFFICIENT MIXING AND GRANULATION OPTIMIZED TO YOUR PROCESS

 Open the catalog to page 1
PHARMX® HIGH SHEAR GRANULATOR-2

MAXIMIZE YOUR BATCH DESIGN FLEXIBILITY ENSURES PEAK PERFORMANCE FOR HIGH SHEAR GRANULATING MIXERS Whether you need solid dosage technology for R&D, pilot or production applications, Fluid Air can help. Our PHARMX® high-shear granulating mixer can be quickly and cost-effectively customized to meet your unique processing challenges. Processing ingredients with special requirements? One pot processing? Let us help you optimize your production. BENEFITS: • Simplify your scale-up • Minimize process downtime • Optimize production • Reduce maintenance • Improve product quality What is High-Shear Granulation?...

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PHARMX® HIGH SHEAR GRANULATOR-3

EFFICIENT GRANULATING AT UP TO 90% BOWL CAPACITY Mixing Impeller System PROCESSING POWDERS, GRANULES, AND LIQUIDS TO REQUIRED SPECIFICATIONS The PHARMX® high-shear granulator has a mixing bowl with a bottom-driven mixing impeller and side mounted chopper. The bowl geometry is optimized to permit working volumes from 30-90% of full capacity. EFFICIENT, HOMOGENEOUS MIXING EVEN AT LARGER CAPACITIES CREATING A QUALITY PRODUCT The dome shaped lid permits product to perform a complete roll over as it moves up the side of the vessel wall. This ensures efficient mixing even when running at larger operating...

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PHARMX® HIGH SHEAR GRANULATOR-4

EASY TO USE BATCH ARCHITECT TM PROCESS CONTROL SOFTWARE MAXIMIZES OPERATING FLEXIBILITY • Simple enough for R&D scale machines; sophisticated enough for applications requiring 21 CFR Part 11 FDA compliance • Configure for manual control or optional phase or recipe-based control • Runs on Allen-Bradley® Logix processors, RSLogixTM 5000 Software, PanelView PlusTM or FactoryTalk® SE Platform Batch Architect ProTM Status Screen Allen-Bradley is a trademark of Rockwell Automation PHARMX® HIGH-SHEAR GRANULATING MIXER SYSTEMS: SPECIFICATIONS Total bowl volume (L) Charge- max. liters @ light bulk, 0.3...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.