Size Reduction Mill with Flexible Containment Option for High-Potency Compounds GRANUMILL® JR. Features & Benefits • Three interchangeable rotor designs available (square/flat, round, and knife) and fine feed control with optional screwfeeder for tighter control over particle size distribution • GMP design and quick-release housing allow entire mill to be broken down in minutes for cleaning • Virtually identical tip speed from R&D through production scale ensures easy scale-up and validation • Approved for USDA 3A applications including dairy processing Flexible Containment Option Advantages Customizable. Versatile. Cost-Effective. GRANUMILL® JR. size reduction systems meet FDA SUPAC (Scale-Up and Post-Approval Changes) guidelines for both impact and screening mills, allowing for low-RPM screening of agglomerates in addition to high-speed impact milling. The mill’s versatile design combined with the new, removable containment option provides users with the flexibility to run a variety of processes for a wide range of applications on a single, cost-effective system. In cooperation with ILC-Dover, we are able to provide custom-designed solutions for the containment of hazardous APIs in R&D size reduction applications. • Flexible enclosure set-up allows for use in both containment and non-containment applications, eliminating the need to purchase a second machine solely for containment use • Capable of meeting an OEB5 classification • Achievable containment level of 1.0 µg/m3 on a task basis

Configurable to Meet Your Process Requirements Additional custom options for the GRANUMILL® JR. include: Finished particle size mesh (micron) • Nitrogen-inerting systems Throughput ((lbs/kg)/hour) System height (inches/mm) System width (inches/mm) System length (inches/mm) Screen width (inches/mm) • Screwfeeding systems • Water jacketing • Explosion-proof construction • In-line or portable base configurations Containment width** (inches/mm) Containment depth** (inches/mm) Containment height** (inches/mm) *Dimensions include screwfeeder **Allow 36 inches/915 mm on side for pass-through port Additional...