FE CPS
FE CPS
- Expertise and Support: Offers formulation consulting, process optimization, and regulatory support.
- Technology Integration: Seamless integration of Process Analytical Technology (PAT) for quality control.
- Modular and Flexible Design: The FE CPS can be installed in various configurations, either horizontally or vertically, and is adaptable to different production needs.
- Compact and Economical: Designed to fit into standard production rooms, reducing space and cost requirements.
- Simple Operation: The TRI.EASY Operating Concept ensures ease of use, with intuitive interfaces and minimal training requirements.
- Fast Changeovers: Enables quick product changeovers and cleaning, enhancing production efficiency.
- Safety and Containment: Features dust-tight enclosures and strict separation of process and technical areas to ensure safety.
- Material Feed: Utilizes gravimetric feeding stations for precise ingredient dosing.
- Mixing Process: Features a novel dosing-blending-conveying module with two independent mixing zones for homogenization and fine distribution.
- Powder Transport: Uses a dense-phase conveying system to prevent segregation during transport to the tablet press.
- Flexible and Modular: Capable of handling various formulations and production scales.
- Compact Design: Reduces the need for extensive modifications and space.
- Controllable and Safe: Embedded PAT ensures continuous quality monitoring, and the design provides maximum operator safety.
- Fast and Efficient: Quick changeovers and cleaning processes minimize downtime.
- Throughput capacity ranges from 5–250 kg/h with a single rotary tablet press and 5–400 kg/h with a double rotary tablet press, depending on formulation and tablet.
- The system can accommodate 1 to 6 dosing stations and has 2 blender mixing zones.
- Various feeder-blender funnel configurations are available, dependent on formulation.
- Ingredient characteristics include a powder density range of 0.2 ~ 1.0 kg/l.
- Electrical supply requires an operating voltage of 400 – 480 V, frequency 50/60 Hz ±5%, with a power supply of 3 phase + PE and power of 9 kW.
- Compressed air supply is 6 bar / 300 l/min peak volume flow, with an air extraction rate of 50 m3/h and negative pressure of –10 hPa.
- Machine dimensions include a height of 2,300 mm, ingredient inlet height of 2,355 mm, and total height including blend conveyor arm of 3,000 mm. The weight is approximately 4,900 – 5,200 kg depending on configuration.
- Offers tailored modules for every phase of the tableting process, from development to maintenance.
- Includes standard modules and customized training programs, certification according to 21 CFR, and flexible delivery options.
- Guides from powder analysis to validated serial production, minimizing scale-up risks and shortening time-to-market.
- Offers efficient formulation development, production-like process development, seamless scale-up, and secure technology transfer.
- Ensures quality and efficiency in tableting, enabling reliable continuous production.
- Models include FE35 for small batches, FE55 as an all-rounder, and FE75 for maximum output.
- Provides solutions for higher performance and easy handling, with cross-generation system compatibility.
- Models include F10i for smaller batches, F20i for high-performance applications, and F30i for large batches.
- Offers comprehensive support from initial commissioning to process optimization.
- Includes technical support, fast spare parts management, data-driven process optimization, and machine modernization.
- Provides contact details for Fette Compacting offices across Europe, Asia, North America, Latin America, and Africa.
Catalog excerpts
FE CPS The New Standard in Continuous Direct Compression
Open the catalog to page 1
together *0 from lab to production Better together - from lab to production For more than 75 years, Fette Compacting has been redefining precision in industrial tablet production. As the world market leader in integrated solutions for OSD (Oral Solid Dosage) manufacturing, we deliver decisive competitive advantages. Our portfolio ranges from high-performance tablet presses to specialized Containment solutions and process equipment. But technology is only one part of our DNA. Guided by our principle “Together - from lab to production”, we support you throughout the entire life cycle of your products:...
Open the catalog to page 2
Continuously Better Production The most economical solution for OSD production – compact, safe, and efficient The production of pharmaceutical solids is undergoing a paradigm shift: The transition from batch processing to Continuous Manufacturing delivers efficiency and quality advantages but has been held back, among other things, by complex system design. With the FE CPS, Fette Compacting presents a solution that rethinks Continuous Direct Compression from the ground up. Thanks to these advantages, the FE CPS paves the way from lab to series production. For the first time, it makes Continuous...
Open the catalog to page 3
The Process: Efficiency in Flow Dosing and mixing without deviations The FE CPS redefines material flow. Instead of mixing tanks and complex transfer systems, the machine relies on a lean, continuous stream. Using Loss-in-Weight feeders, the FE CPS doses different powders with precision. The intelligent control system synchronizes dosing, mixing, and transport in real time, ensuring that the material is always correctly blended before it reaches the tablet press. 1. Material feed Precision begins at the inlet. Up to six gravimetric feeding stations (Loss-in-Weight feeders) feed the active ingredients...
Open the catalog to page 4
Reinvented in Seven Areas Key advantages of the FE CPS at a glance Maximum flexibility in installation and use: As stand-alone or integrated into a line Single-level setup – no elaborate modifications or platforms required TRI.EASY Operating Concept makes operation, maintenance, and changeover easy, safe, and fast Universal process design for processing numerous formulations – from 5 to 250 kg/h with a single rotary tablet press and 5 to 400 kg/h with a double rotary tablet press Dust-tight enclosures and strict separation of process and technical areas for effective Containment Minimal changeover...
Open the catalog to page 5
Modular Adapts to your facility and your process The modular design of the FE CPS provides enormous versatility – both during installation and across various manufacturing processes. It integrates seamlessly into any type of downstream powder processing, be it a tablet press or a granulation system. The FE CPS is equally efficient in stand-alone mode, producing high-quality powder blends fed directly into Intermediate Bulk Containers (IBC). Flexible installation options For integration into existing facilities, the FE CPS offers maximum flexibility: + Horizontal setup (1 level): The machine can...
Open the catalog to page 6
Compact Achieve great things in a small space Space is expensive – especially in cleanrooms. The FE CPS is an extremely compact unit that fits into a standard production room. Expensive modifications, high ceilings, or complex operator platforms and stairs are a thing of the past. Easy installation cuts costs The machine can be moved through standard doors and is ready to operate with a simple plug-and-play connection. This dramatically reduces initial capital expenditure (CAPEX) while also lowering ongoing operating expenses (OPEX) due to a smaller floor area and simpler climate control. Whether...
Open the catalog to page 7
Continuous Manufacturing does not have to be complicated. In line with the TRI.EASY Operating Concept from Fette Compacting, the FE CPS is so streamlined and standardized that personnel with tableting experience can start working with it right after an introductory training session. Operators start, run, stop, disassemble, and clean the FE CPS the same way they would a tablet press. This also makes product changeovers safe and swift. All necessary calibration and maintenance tasks are carried out in the technical area - with no product contact. HMI makes operation intuitive The HMI operating...
Open the catalog to page 8
Flexible From lab trial to series production Thanks to Quality by Design (QbD), the FE CPS is a true multi-talent. Based on the design criteria established during development, throughput of 5 to 250 kg/h with a single rotary tablet press and 5 to 400 kg/h with a double rotary tablet press can be achieved. The stated upper limits, however, depend heavily on the specific material properties and formulation. The FE CPS is designed for both production and R&D, deepening product and process understanding at every stage of development. In practice, our collaborative projects have frequently yielded...
Open the catalog to page 9
Maintenance without entering the process area The technical area of the FE CPS houses all drives, motors, sensors, valves, electrical and pneumatic components - essentially everything that does not come into contact with the product. It is easily accessible from the rear of the machine for inspections or maintenance work, all without opening the process area. Technical personnel can carry out their tasks without breaching Containment. The FE CPS is fully prepared for processing potent active ingredients. Its innovative design uses a stainless steel wall to strictly separate the process area (front)...
Open the catalog to page 10
Fast Product changeover and cleaning in record time Time is money – and that goes for product changeovers too. The FE CPS enables a complete changeover including cleaning in less than one shift. Thanks to the TRI.EASY Operating Concept, all product-contact parts (feeder, mixer, funnel) are lightweight and can be quickly removed by a single person without tools. The total number of removable elements is kept to a minimum and they are easily transported to a wash room. Continued operation with a changeover set The empty process area that remains is easily accessible, compact, and has smooth walls,...
Open the catalog to page 11
