Dissolution Guide Our broad range of dissolution testers
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Dissolution Guide Our broad range of dissolution testers

Our Dissolution Program USP 1-7 ERWEKA offers dissolution testers for every single harmonized USP/EP/JP dissolution method – starting from USP 1 up to USP 7. We offer a broad range of dissolution testers - from manual testing with the DT 126 / 128 Light up to the high-volume tester DT 1610 Series. Dissolution Systems Our semi-automated dissolution systems are available as Offline, Online and On-/Offline Systems for UV-Vis and HPLC analytic. Every dissolution system needs a pump – we offer several options suited to different needs. Fully automated Dissolution System RoboDis II The...

Media Preparation We offer the perfect companions to your dissolution tester for fast media preparation and filling of vessels. World exclusive Our dissolution tester for testing of in vitro release of substances into surrounding liquid medium. The RRT 10 BioDis for automatic dissolution testing of different extended and sustained release dosage forms. USP 4 USP method 4 is supported by our Flow-Through Cell DFZ ll, available as stand-alone or as a system. Dissolution Options ERWEKA offers a broad range of options for all of its dissolution testers and systems. 3 Dissolution Guide Our...

USP methods overview USP method 1 – Basket USP method 3 – Reciprocating Cylinder USP method 4 – Flow-Through Cell ■ mmediate / Extended and I delayed release forms ■ Tablets ■ Capsules ■ Beads ■ Floating dosage forms ■ Agitation method: Rotating Stirrer ■ ots of experience (oldest L method, more than 200 monographs in USP) ■ No sinker necessary ■ pH change possible Tablets Capsules Beads I mmediate / extended and delayed release forms ■ Agitation method: Rotating Stirrer ■ Lots of experience ■ Easy to use and robust ■ pH change possible ■ Easy pH change ■ ydrodynamic can be H influenced by...

USP method 5 – Paddle over Disk ■ Standard equipment (USP 2 - paddle can be used) USP methode 6 – Rotating Cylinder ■ Transdermal patches ■ Agitation method: Rotating Stirrer ■ tandard equipment can S be used ■ Variable volumes ■ Big patches useable USP method 7 – Reciprocating Holder ■ Transdermal patches ■ xtended release dosage E forms ■ pH profiles ■ Agitation method: Reciprocation ■ Small volumes possible ■ Holder can be varied ■ Easy pH change Transdermal patches Floating dosage forms Ointments Emulsions Agitation method: Rotating Stirrer Different holder types: ■ Acrylic Rod:...

Test station positions Schematic view of ERWEKA test stations ERWEKA’s dissolution tester can be equipped with 6 or 8 (12 or 14) test stations. Even though all of the testers are offered with a different number of stations, they differ from product line to product line. The dissolution tester DT 126 light comes with a fixed number of 6 test stations, its bigger sibling, the DT 128 light comes with 8. The dissolution testers of the DT 950 and 820 series always come with inlets for 8 vessels, which are covered with blinds, if a DT with 6 test stations is ordered. Dissolution testers with less...

Low-head, high-head und cleaning position ERWEKA’s dissolution testers DT 950 / DT 820 offer two different operating modes which differ by the position of the head, and a third position for cleaning. Shaft high-head for PTFE paddle & basket Shaft low-head for PTFE paddle Shaft low-head for paddle & basket Low-head operating mode (LH) Shaft high-head for paddle & basket The low-head mode on DT 950 / DT 820 is the standard mode and usually comes in conjunction with a system configuration with automated sampling station (ASS-8). Benefits are the closed vessels and therefore low evaporation....

Manual dissolution testing, simple and compact DT light Series The ERWEKA DT light Series delivers the proven ERWEKA quality in a comprehensive package for a budget for simple dissolution testing with USP method 1, 5 and 6. The DTs are equipped with 6, 8 or 12 test stations and a fixed drive head (highhead), allowing easy access to each 1000 ml vessel. The shafts can be replaced easily and the unique water bath of moulded PET is equipped with the time-proven ERWEKA water outlet for easy cleaning. The external flow through heater reduces the influence of external vibrations and ensures a...

DT 126 light Specifications ■ igh-head with 6 test stations H ■ imensions (width / depth / height): D 510 mm / 450 mm / 660 mm ■ Weight: 30 kg DT 128 light Specifications ■ igh-head with 8 test stations H ■ imensions (width / depth / height): D 642 mm / 482 mm / 680 mm ■ Weight: 38 kg DT 1212 light For high volume testing Specifications ■ igh-head with 12 test stations H ■ imensions (width / depth / height): D 932 mm / 444 mm / 656 mm ■ Weight: 60 

The new DT 950 Series Digital today. For the challenges of the future. The ERWEKA DT 950 Series is our first digital dissolution tester on the market, equipped with the most advanced technology for the requirements of today and the challenges of tomorrow. With state-of-the-art embedded PC technology, the DT 950 is the first of its kind. The 7" touch display with a modern user interface focuses the user on the most important task the DT 950 has to fulfill - 100% USP/EP/JP compliant dissolution testing, without distractions and errors. For this purpose, we have designed the ERWEKA TestAssist,...

Digital embedded PC technology The digital embedded PC technology offers all advantages and unlimited possibilities of modern software programming making the DT 950 is more future-proof than ever before. In the first step, this means simple network printing and a modern user interface. In the future, the DT 950 Series will be expanded with additional functions and can thus constantly adapt to the user‘s requirements and future industry 4.0 developments. Modern user interface with TestAssist The new, modern user interface of the DT 950 focuses the user on the most important function of the...