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Bioprocess Catalog

Bioprocess Catalog
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Bioprocess Catalog

Product catalog summary
Introduction
Eppendorf Bioprocess Products are designed to enhance the development and production of treatments in cell and gene therapies and stem cell-derived products. The catalog underscores the significance of bioprocessing in advancing these technologies and Eppendorf's dedication to providing innovative solutions.
Bioprocess Solutions
Eppendorf offers a variety of bioprocess solutions, including single-use stirred-tank bioreactors, which are considered the industry standard. These solutions are complemented by equipment, training programs, and application services to assist scientists in overcoming cultivation challenges.
Product Categories
The catalog is divided into several key sections:
  • Monitoring & Control Systems: Includes DASbox® Mini Bioreactor System and DASGIP® Parallel Bioreactor Systems.
  • Bioreactors: Features BioFlo® series and BioBLU® Single-Use Bioreactors.
  • Software: Offers BioCommand® SCADA Software and DASware® suite for control and analysis.
  • System Accessories: Includes sensors, feeding accessories, and performance plans.
  • Service: Comprehensive service solutions, including preventive maintenance and training.
Application Support
Eppendorf provides high standards of technical and application support, including a knowledge base with application notes, FAQs, and videos. Training is recommended for new customers and can be customized to specific needs.
Digital Tools
The Eppendorf App enhances user experience with features like product registration, AR for virtual product placement, and environmental impact calculations.
Bioprocessing Applications
The catalog highlights applications in vaccine development, antibody/hormone production, and stem cell technologies, supporting flexible and optimized processes to balance costs and time-to-market.
Scale-Up Strategies
Effective scale-up strategies are crucial for maintaining reproducibility in bioprocessing. The catalog discusses the Constant Power approach and the use of the BioFlo® 720 Bioreactor Control System for scaling up CHO cell cultures.
Conclusion
Eppendorf's bioprocess solutions and services are designed to support the biopharmaceutical industry in developing and scaling up processes efficiently, ensuring consistent yields and optimized performance.
Bioprocess Control Systems
The SciVario® twin bioprocess controller is highlighted for managing complex microbiological and cell culture processes using both glass and single-use vessels. Experiments with E. coli demonstrate its versatility across different vessel sizes.
Stem Cell Technologies
Human induced pluripotent stem cells (hiPSCs) are emphasized for their potential in drug discovery and development, with large-scale manufacturing of cardiomyocytes using stirred-tank bioreactors.
Adoptive Cell Therapy
The use of stirred-tank bioreactors for expanding CD4+ T cells is explored, crucial for adoptive cell therapy in treating viral infections and cancers.
Exosome Isolation
A method for isolating exosomes from stem cells using single-use bioreactors and ultracentrifugation is described, noted for its efficiency and speed.
Vaccine Production
The production of vaccines using suspension cell culture platforms is discussed, highlighting the use of the SciVario twin Bioreactor Control System for producing AAV vectors.
Technical Specifications
Detailed specifications for various bioreactor models, including DASbox® Mini Bioreactor System and BioFlo® series, are provided, covering aspects like working volumes, vessel types, and control features.
Applications
These systems are suitable for a variety of applications, including mammalian, stem, insect, and plant cell cultivation, bacterial and fungal fermentation, and specialized applications like vaccine production and biofuel development.
Service and Maintenance
Regular maintenance by qualified engineers is emphasized to ensure reliable operation and avoid costly repairs. Service plans include Essential Check, Advanced Maintenance, and Premium Service, each with specific tasks and checks.
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Catalog excerpts

Bioprocess Catalog-1

Eppendorf Bioprocess Products

 Open the catalog to page 1
Bioprocess Catalog-3

»We help bring life-saving treatments to the world.« Lina Tao - Head of Bioprocess Unit, Eppendorf SE Bioprocess engineers develop and produce a multitude of products and ingredients available today. Their applications are diverse and the products can be found in the pharmaceutical, chemical, and nutritional industry. Within those branches, promising new bioprocess approaches, such as cell and gene therapies (CGT) or stem cell-derived novel food, start gaining momentum and open the door towards a new tomorrow. The progresses in the CGT field hold great potential to revolutionize how we will live...

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Bioprocess Catalog-4

> DASbox® Mini Bioreactor System > DASGIP® Parallel Bioreactor Systems > BioBLU® c Single-Use Bioreactors 58 - 61 > BioBLU® f Single-Use Bioreactors 62 - 65 > BioBLU® Single-Use Bioreactors Adaptor Kits 66 - 67 > DASbox® Mini Bioreactor 68 - 69 > DASGIP® Bioblock / SciVario® twin Spinner Vessels 70 - 71 > DASGIP® Bioblock / SciVario® twin Stirrer Vessels 72 - 73 > SciVario® twin Benchtop Bioreactors for Cell Culture 74 - 75 > SciVario® twin Benchtop Bioreactors for Microbiology 76 - 77 > DASbox®, DASGIP®, and SciVario® twin Bioreactor Accessories 78 - 89 > BioFlo® 120 Bioreactors Accessories...

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Bioprocess Catalog-5

SYSTEM ACCESSORIES 136 - 171 > Fibra-Cel® Disks > DASGIP® EGC for Exhaust Condensation > DASGIP® Peltier Exhaust Condensers > DASGIP® Feeding Accessories > Optical Density Sensors SERVICE 172 - 217 > DASbox® Mini Bioreactor System Performance Plans > DASGIP® PHPO and OD4 Performance Plans > DASGIP® GA Performance Plans > DASGIP® TC4SC4 Performance Plans > DASGIP® MP8 and MP4 Performance Plans > DASGIP® MX4/4 Performance Plans > DASGIP® MX4/1, MF4 and Rotameters Performance Plans > DASGIP® PBR4 Performance Plans > DASGIP® Control System Performance Plans > SciVario® twin Performance Plans > DASGIP®,...

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Bioprocess Catalog-6

epServices for premium performance Eppendorf Services At Eppendorf Services, we are committed to providing sincere, reliable services and tools to help you maintain premium performance, and maximum safety of your Eppendorf instruments and your workflows. This includes a comprehensive range of carefully designed service solutions performed by our dedicated bioprocess service teams worldwide. With our services, we complement our bioprocess portfolio with Technical and Application Support, Training, and Maintenance Services.

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Bioprocess Catalog-7

Application Support Knowledge Base A comprehensive collection of bioprocess-related application notes, FAQs, and videos can be found on our website under Knowledge Base and Applications. Bioprocess Performance Plans Technologically demanding products require first-class service to ensure that the results they produce are optimized. Customers can rely on Eppendorf Service for superior support for their bioprocess products, beginning with startup of the system. The services range from technical support and troubleshooting to delivery of replacement parts on short notice and customer-specific maintenance...

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Bioprocess Catalog-8

Our Bioprocessing Solutions for Your Applications: Discover our www Website www.eppendorf.link/bioprocess Information on bioprocessing is now available in a central location: Find research examples, application notes, and white papers on topics like bioprocess development, stem cell cultivation, scale-up, and many more. Get to know our customers working in biopharmaceutical, biochemical, and food/feed laboratories. Get engaged in webinars, see our training offerings and do not miss any news and events related to bioprocessing. Vaccines There is a rising demand for development of new vaccines....

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Bioprocess Catalog-9

Bioprocess Knowledge Hub Whether you are just starting in bioprocessing or have numerous years of experience in the field, it can be a vast area with many aspects to consider. Find information on general bioprocessing topics like bioprocess monitoring and control and scale-up, as well as expert advice on how to optimize bioprocessing for specific applications, including cell culture and microbial fermentation. Become an expert in bioprocessing. Join us at www.eppendorf.link/bioprocess-basics

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Bioprocess Catalog-10

Recent Application Notes Resolving Cultivation Bottlenecks: The Bioprocessing Journey Bioprocessing relies on living cells or their components to create pharmaceutical, biofuel, or nutrition products. Whether bacterial, fungal, plant or mammalian, cells used for these processes need unique conditions for optimal growth and product formation. This eBook describes the advantages of using bioreactors and highlights different aspects that need to be considered when working with a bioreactor. RESOLVING CULTIVATION BOTTLENECKS: The Next Level: Why Move to a Bioreactor How Do Bioreactors Boost Reproducibility?...

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Bioprocess Catalog-11

APPLICATION NOTE No. 409 I April 2019 Controlled, Large-Scale Manufacturing of hiPSC-Derived Cardiomyocytes in Stirred-Tank Bioreactors Yang Jiang1, Karin Langenberg1, Viola Borgdorff1, Marta Duńska1, Robert Post1, Oscar Bartulos1, Mieke Doornbos1, Stefan Braam1, Arie Reijerkerk1 1 Ncardia BV, Leiden, The Netherlands; 2Ncardia Inc, Wayne, PA USA; Contact: [email protected] Ulrike Rasche³ ³Eppendorf Bioprocess Center Juelich, Germany; Contact: [email protected] Abstract Effective drug discovery and development relies in large part on the availability of predictive preclinical model...

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Bioprocess Catalog-12

Solutions that grow with you From the parallel mini bioreactor system for early stage bioprocess development, the benchtop and parallel bioreactor systems for the laboratory scale to the sterilize-in-place solutions for production: Eppendorf offers users from industry and research extensive bioprocess solutions from a single source and meets the highest quality demands. i For more information go to www.eppendorf.link/bioprocess Technical specifications subject to change.

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