Compact Modulators Product Guide Compact Modulators Product Guide Case Study: TomoTherapy Inc. Sales and support offices Europe: Regional sales office e2v 106 Waterhouse Lane Chelmsford Essex, CM1 2QU England T +44 (0)1245 493493 F +44 (0)1245 492492 E-Mail: [email protected] TomoTherapy Inc. was founded in 1997 by two members of the University of Wisconsin’s intensity – modulated radiotherapy (IMRT) research group. Cancer hospitals across the globe are today using the progressive TomoTherapy® Hi-Art® treatment system in the fight against cancer. This equipment integrates the treatment planning, on-board computed tomography for patient positioning and the delivery of IMRT – a key recent advance in radiation therapy – from the same system. Patients with tumours that are untreatable with conventional systems can now receive radiotherapy treatments from the Hi-Art® treatment system. In order to generate the prime energy required by the system’s accelerator, which delivers the X-rays used in the imaging and treatment of tumours, US-based TomoTherapy needed help from a global supplier. TomoTherapy required an advanced RF power system capable of delivering 3MW of peak microwave power to fit within the confined space of their system, which uses a patented and unique rotating gantry concept to deliver complex treatments. The potential to offer remote diagnostics and system management in the future was also a requirement of TomoTherapy. e2v’s magnetron and high power electronics groups worked closely with TomoTherapy to provide them with a solution that suited their specific needs. e2v’s advanced RF system consists of a solid-state compact modulator, a magnetron with electro-magnet and a microwave launching section, and provides the high energy, pulsed microwave source required to drive the accelerator, which in turn provides the life saving X-rays used in tumour imaging and treatment. Bob Evensen, Director of Manufacturing at TomoTherapy, comments: “We selected e2v on the merits of its forward thinking technology. e2v’s modulator is highly compact in design, making it ideal for our system. Early results showed the solid-state modulator to be more stable than line-type modulators. Furthermore, its computer-controlled and detailed diagnostics capability is a significant advantage for rapid diagnostics, something that could potentially be managed remotely in the future. It fits our requirements precisely.” Today, TomoTherapy has over 130 “clinical sites”, meaning they have been fully tested and are currently being used for patient treatment. As a result, over 2,500 patients each day are currently treated using a TomoTherapy® Hi-Art® treatment system, and this figure is increasing daily. Bob Evensen reflects: “Being able to provide so many patients with highly conformal, image-guided IMRT radiotherapy treatment truly reflects the progress that TomoTherapy and e2v have made to date. Our relationship is truly a partnership in all aspects of reliability, quality, features, and cost.” Compact Modulators Product Guide

Compact Modulators Product Guide Introduction e2v has a long history of manufacturing components for high-voltage modulator systems. We now offer a range of compact modulators based around our patented solid-state switching technology. e2v has a very strong high-voltage electronic engineering pedigree which has successfully been used to supply enabling technology to its customers, allowing them to maintain leading positions in the markets in which they operate. Over the last decade e2v has designed and developed a range of high power pulsed systems for radar and for linear accelerators used in...