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Doric Lenses
Hardware Catalog SFN2019

Hardware Catalog SFN2019

Product catalog summary

Overview: The document is a comprehensive catalog of Doric Lenses' neuroscience instrumentation, focusing on optogenetics and neuro-photonics products. It highlights the evolution from basic light stimulation hardware to complex systems integrating fiber-optic networks for brain research.

Light Generation & Control: This section details various illumination technologies, including LED and laser diode systems. LEDs are emphasized for their role in optogenetic experiments, providing uniform illumination for fluorescence microscopy and fiber photometry. Connectorized LEDs are highlighted for their efficiency and compatibility with optical fibers, featuring EPROM memory for automatic current setting and active cooling options.

LED Modules: Connectorized LEDs are designed for high brightness and efficient fiber coupling. They include safety features like automatic current setting and active cooling for high-power applications. The document provides specifications for output power and wavelength, ensuring optimal performance in neuroscience experiments.

LED Drivers: Doric offers programmable LED drivers in multiple channel configurations, supporting both continuous wave and pulsed operations. Advanced features include TTL modulation and software-defined sequences, enhancing flexibility in experimental setups.

Combined LEDs: These modules merge multiple LED colors into a single output, using a patented mirror configuration for high coupling efficiency. They are customizable for various opsin activation wavelengths, supporting up to four distinct wavelengths in a single device.

Rotary Joints: The integration of LEDs with fiber-optic rotary joints minimizes light loss and mechanical stress, crucial for experiments with freely-moving animals. The document outlines options for combined LEDs with rotary joints, facilitating multi-wavelength light activation.

Applications: The catalog presents various neuroscience applications, including optogenetic stimulation, fiber photometry, and fluorescence microscopy. It emphasizes the integration of these methods with electrophysiology for comprehensive brain activity monitoring.

Specifications and Components: The document outlines various components and specifications related to LED and laser diode technologies used in fiber optic systems. Key components include Combined LEDs with Fiber-optic Rotary Joint, LED Fiber Light Sources, Connectorized Laser Diode Modules, and Ce:YAG Fiber Light Sources. Each component has specific ordering codes and compatibility requirements, such as the need for compatible holders and drivers.

LED Fiber Light Sources: These sources are available in 1-, 2-, and 4-channel models, with each LED having its own output FC connector. The document provides ordering codes and notes that the typical output power of each LED is detailed in a separate table.

Connectorized Laser Diode Modules: These modules are designed for use with multimode optical fibers and have specific size and connection requirements. They include an EPROM memory for device recognition and maximum current setting to prevent overdrive. The document lists available wavelengths and power values.

Laser Diode Module Drivers: Available in 1-, 2-, and 4-channel models, these drivers can be controlled manually or via USB. They feature safety mechanisms such as interlock connectors and key switches. The drivers automatically recognize connected modules and set appropriate driving currents.

Ce:YAG Fluorescent Illumination: This section describes the use of Ce:YAG crystals for generating white light through blue laser diode pumping. The Ce:YAG Fiber Light Sources are optimized for coupling into small core optical fibers and are suitable for optogenetics and fluorescence microscopy.

Optical Heads and Drivers: The document details the specifications of Ce:YAG Optical Heads, including their compatibility with different fiber core diameters and numerical apertures. It also lists available drivers and their features, emphasizing the importance of eliminating leakage current for optogenetics experiments.

Tables and Data: The document includes several tables providing detailed specifications such as output power, irradiance, and ordering codes for various light sources and components. These tables are crucial for selecting the appropriate components based on specific application requirements.

Overview: This document provides detailed information on optogenetics methods, focusing on light modulation techniques using TTL pulse generators, mechanical shutters, beam splitters, and other optical components. It highlights the specifications, applications, and ordering codes for various products used in optogenetics experiments.

Optogenetics TTL Pulse Generators (OTPG): These devices are essential for creating programmable light pulse trains in optogenetics experiments. They connect to computers via USB and to light sources or shutters via BNC cables. The pulse parameters are controlled using Doric Neuroscience Studio Software. Two models are available: 4-channel and 8-channel OTPGs.

Mechanical Shutter Heads and Adapters: Mechanical shutters are used for modulating continuous light beams, especially in laser-based setups. The document describes two models: Stanford Research Systems Model SR475 and Vincent Associates Uniblitz Model LS-2, each with specific specifications and compatible adapters.

Beam Splitters/Combiners: These components are crucial for dividing or combining light signals in fiber optic circuits. The document introduces Doric Mini Cubes and Micro Splitters for intensity and wavelength division, highlighting their compact design and efficient coupling capabilities.

Light Intensity Distributors and Spectrum Mixers: These devices are used to distribute light intensity across multiple channels or to mix different spectral lights into a single beam. They are designed for use with multimode fibers and offer low insertion and polarization dependent loss.

Beam Modifiers: The document discusses various beam modifiers, including connectorized U-brackets for filtering and NA converters for adjusting beam geometry. These tools are essential for customizing light delivery in optogenetics experiments.

Rotary Joints: Fiber-optic rotary joints are described as essential components for maintaining stable light input in freely-moving optogenetics experiments. They prevent fiber damage and minimize light fluctuations during rotation.

Overview: The document provides detailed specifications and usage guidelines for various types of fiber-optic and electrical rotary joints used in optical and electrophysiological experiments. These rotary joints are essential for transmitting light and electrical signals between stationary and moving components in experimental setups.

1x1 Fiber-optic Rotary Joints: These joints are designed for use with optical fibers with a core diameter of 200 µm and a numerical aperture (NA) of up to 0.5. They ensure minimal transmission variation, which is crucial for fiber photometry experiments. The transmission efficiency is over 85%, with a maximum variation of ±3%.

Pigtailed 1x1 Fiber-optic Rotary Joints: These joints are optimized for minimal transmission variation using large core multimode fibers. They are available with different fiber diameters and NA values, ensuring a transmission efficiency of over 70%.

1x2 Fiber-optic Rotary Joints: These joints split light from a single input fiber into two output fibers, available in intensity and wavelength division versions. The intensity division version is useful for bilateral stimulation experiments, while the wavelength division version is suitable for separating different spectral bands.

Separate Light Path 2x2 Fiber-optic Rotary Joints: These joints allow independent control of two different sites of illumination or detection, offering over 80% transmission efficiency per channel.

1x4 Fiber-optic Rotary Joints: Designed to distribute light from a single input fiber to four different regions, these joints are used in experiments involving moving animals.

Electrical Rotary Joints: These joints transmit electrical signals and can be combined with fiber-optic rotary joints for optogenetics experiments. They feature a central aperture for fiber-optic patch cords and offer low torque for minimal mechanical stress.

Assisted Electrical Rotary Joints: These joints provide frictionless operation, making them suitable for small animals like mice. They are available in 12 or 24-channel models and are used primarily in electrophysiology.

Fiber-optic & Electric Rotary Joints: These hybrid joints combine optical and electrical channels, facilitating experiments that require both light stimulation and electrophysiological recordings.

Key Specifications: The document includes detailed tables with specifications such as transmission efficiency, start-up torque, input/output NA, and ordering codes for each type of rotary joint.

Overview: The document provides detailed specifications and options for various types of rotary joints used in fiber-optic and electric applications, particularly in experiments involving freely-moving animals. These rotary joints are designed to minimize mechanical stress and ensure stable transmission of signals.

1. Rotary Joints Specifications:

Transmission efficiency is around 80% with a maximum variation of 2%.
Start-up torque varies depending on the number of contacts, with values of 0.9 mN·m for 6 contacts and 1.8 mN·m for 12 contacts.
Contact material is gold, with a maximum current of 2 A per contact and contact resistance below 500 mΩ.
Rotation speed can reach up to 300 rpm.

2. Assisted Fiber-optic & Electric Rotary Joint:

Electrically driven to follow animal movements, reducing frictional force.
Available with 12 or 24 electrical channels and one optical channel.
Includes features to minimize chromatic aberration and optical aberration.
Transmission rates are 75% for 12-channel and 85% for 24-channel models.

3. Pigtailed Assisted Fiber-optic & Electric Rotary Joint:

Designed for stable transmission in applications like fluorescence microscopy.
Transmission rates vary from 45% to 70% depending on the model.
Includes a holder and compatible mating adapter sold separately.

4. Assisted 1x2 and 2x2 Fiber-optic & Electric Rotary Joints:

1x2 model splits a single fiber-optic channel into two, used for bilateral optogenetic stimulation.
2x2 model allows independent activation of two brain regions, with near-zero crosstalk.
Both models include holders and output patch cords.

5. Fiber-optic & Liquid Rotary Joints:

Combines fiber-optic and liquid delivery for deep brain manipulation.
Includes a 1-channel fluid swivel, with options for 2- or 5-channel swivels.
Transmission efficiency is 60-65% with additional power drop when tubing crosses the light path.

6. Fiber-optic Patch Cords:

Used to connect light sources and rotary joints in optogenetics experiments.
Various specifications available, including core diameter and numerical aperture (NA).
Attenuating patch cords are available for applications requiring reduced optical power.

Specifications: The document provides detailed specifications for various types of fiber-optic patch cords, including mono, dual, and branching types. Key parameters include fiber-optic codes, fiber lengths, termination codes, and numerical aperture (NA). The fiber-optic codes are detailed in tables, specifying core, cladding, buffer, and jacket dimensions.

Procedures: For low autofluorescence patch cords, a 12-hour photobleaching process is recommended to minimize natural fluorescence. This process is more effective for fibers with hard polymer cladding compared to all-glass fibers. It is advised to repeat this process before each use.

Norms and Recommendations: To minimize autofluorescence, it is recommended to use the shortest possible patch cord length. The document also suggests using specific termination codes for dual fiber-optic patch cords and provides guidelines for selecting appropriate jackets for fiber protection.

Key Data from Tables: Tables provide detailed codes for different fiber-optic configurations, including outer diameter, core, cladding, buffer, and jacket specifications. These tables help in selecting the appropriate fiber-optic patch cords based on specific application needs.

Critical Information:

Optical transmission is specified at a 465 nm wavelength, with reduced transmission at 405 nm.
Low autofluorescence patch cords are designed to minimize fluorescence and are suitable for applications requiring low light interference.
Splitter and bundle branching patch cords are available for applications requiring light distribution across multiple outputs.
Protective jackets are available in various materials for enhanced fiber protection.

Fiber-optic Patch Cord Jackets: This section provides codes for different types of fiber-optic patch cord jackets. The available options include PVC jackets with outer diameters of 2 mm and 3 mm, a lightweight metal jacket, and an armored jacket. Each type has specific mass per meter and product jacket codes.

Low Profile Patch Cord Adapter: The adapter allows for a 90-degree bend within a 6 mm radius without bending the fiber cable, minimizing stress. Specifications include receptacle size, connection types, fiber-optic types, and material composition.

Electrical Patch Cords: These cords ensure interconnection with the electrical part of opto-electric cannulas. They come with different electrical connectors and wire gauges. The ordering code specifies length and connector types.

Opto-electric Patch Cords: These cords connect optical and electrical modalities on a cannula. They are designed to minimize electrical noise and are compatible with common electrophysiological headstages and light sources.

Fiber-optic Cannulas: Used for delivering light into body tissue, these cannulas come in various types, including mono, dual, and two-ferrule cannulas. They are designed for easy connection and disconnection, with options for different fiber types and terminations.

Mono Fiber-optic Cannulas: These consist of a bare optical fiber, a fiber ferrule, and a receptacle or sleeve. They allow for efficient connection with fiber-optic patch cords and are available with different receptacle codes and fiber-optic codes.

Low Profile Cannulas: Designed to minimize height over the animal's head, these cannulas facilitate fiber optic implantation along the antero-posterior plane, reducing pressure during connection/disconnection.

Dual Fiber-optic Cannulas: Featuring two implantable fibers, these cannulas are suited for bilateral brain stimulation. They offer precise alignment and efficient fiber-to-fiber mating, with options for guiding pins or sockets.

Overview: The document provides detailed specifications and ordering information for various types of cannulas used in optogenetics and related experiments. These include Two-ferrule Cannulas, Fiber-optic Array Cannulas, Fiber-optic Cannulas with LED, Optical Fiber Cuffs, Opto-electric Cannulas, and Opto-fluid Cannulas.

Two-ferrule Cannulas: These cannulas are designed for applications requiring precise optical stimulation of two brain centers more than 1.7 mm apart. They offer faster insertion and predefined fiber tip distances. Two types of receptacles are available: sleeve and magnetic connections.

Fiber-optic Array Cannulas: Used in experiments targeting multiple excitation sites, these cannulas can have one-dimensional or two-dimensional fiber arrays. They allow for precise control over fiber distances and protrusion lengths.

Fiber-optic Cannulas with LED: These assemblies integrate an LED with the fiber-optic cannula, providing a lightweight optical source for deep brain illumination. Specifications include maximum current, dimensions, and color codes for different LED wavelengths.

Optical Fiber Cuffs: Designed for optogenetic excitation/inhibition on muscles or nerve fibers, these cuffs use angled mirrors for multiple illumination spots. They are composed of polyimide-based cuffs that can surround the target tissue.

Opto-electric Cannulas: These cannulas combine optical and electrical functionalities, allowing for optogenetics and electrophysiology in freely moving animals. They consist of an optical fiber and a metallic wire electrode.

Opto-fluid Cannulas: These cannulas facilitate the convergence of optogenetics, electrophysiology, and fluid administration. They are available in configurations for single-shot or multiple fluid injections, with options for interchangeable injectors.

Ordering Information: Each type of cannula has specific ordering codes based on fiber-optic codes, fiber lengths, receptacle codes, and other parameters. Custom configurations are available upon request.

Overview: The document provides detailed specifications and ordering information for various types of opto-fluid cannulas, optical injectors, fluid injectors, and related stereotaxic tools used in optogenetics and fluid delivery systems. It includes technical specifications, ordering codes, and compatibility notes for different components.

Specifications:

Tube and Fiber Diameters: The document lists fiber diameters ranging from 70 to 500 µm, with corresponding inner and outer diameters for guiding tubes. Specific fiber-optic codes are provided for different core and outer diameters, along with numerical aperture (NA) and buffer materials.
Optical and Fluid Injectors: Separate ordering codes are provided for optical injectors (OI iOFC) and fluid injectors (FI iOFC) for use with opto-fluid cannulas. The document specifies the need for matching tubing internal diameters with optical injector external diameters.
Dual Opto-fluid Cannulas: These cannulas allow for bilateral implantation with interchangeable injectors. They come with two plugs to prevent clogging and are available in small (S) and large (L) receptacle types based on the pitch between optical fibers.

Procedures and Recommendations:

Stereotaxic Tools: The document describes various stereotaxic cannula holders and adapters designed to maintain precision during implantation. It includes ordering codes for different holder types and notes on compatibility with stereotaxic apparatus.
Optical Fiber Probes: These are used for in vitro and in vivo experiments, requiring thin and long optical probes that connect to micro-manipulator probe holders. The document provides specifications for optical fiber probe holders and tips, including core diameters and NA combinations.
Opto-electric Probes: These probes combine optical and electrical functionalities, with specifications for fiber-optic core diameters, NA, and electrical connections. They are designed to reduce cable congestion and provide precise illumination and recording capabilities.

Key Tables and Data:

Table 72: Lists fiber-optic codes with core and outer diameters, NA, buffer color, and material.
Table 73: Provides ordering codes for stereotaxic cannula holders based on ferrule diameter.
Table 74: Lists in-line adapter ordering codes based on diameter.
Table 75: Provides clamp ordering codes for different diameters.
Table 76: Lists receptacle adapter ordering codes for different attachment diameters.

Conclusion: The document serves as a comprehensive guide for selecting and ordering components for opto-fluid cannulas and related stereotaxic tools, providing detailed specifications and compatibility information to ensure proper integration and functionality in optogenetics and fluid delivery applications.

Overview: The document provides detailed specifications and components for various systems used in optogenetics and electrophysiology, as well as miniaturized fluorescence microscopy. These systems are designed for in vitro and in vivo applications, particularly for single-cell resolution recordings and imaging in head-fixed animals.

Single-cell Optogenetic Illumination and Electrophysiology Recording System: This system combines optogenetics and electrophysiology to record synaptic events at a single-cell level. It includes components such as fiber light sources, opto-electric probe holders, adapters, interconnect wires, and probe tips. The system is capable of activating or inhibiting optogenetic proteins and allows extracellular electrophysiology by using an electrolyte-filled fiber probe.

Miniaturized Fluorescence Microscopy: The document describes systems for fluorescence microscopy that are miniaturized for use in freely moving animals. These systems include snap-in and twist-on models for surface and deep-brain imaging. The systems are equipped with components like LED optical heads, fluorescence microscope drivers, and imaging cannulas. They are designed to work with various fluorophores and allow electronic focus adjustments.

Specifications and Ordering Codes: Detailed specifications for each component, such as optical fiber diameters, lengths, and coatings, are provided. Ordering codes are included for easy reference to specific configurations and components.

Applications and Recommendations: The systems are suitable for neuroscience research, particularly in studying neural circuitry and synaptic events. Recommendations for selecting appropriate microscope bodies and imaging cannulas based on brain zones are provided, along with notes on customization options for cable jackets and lengths.

Overview: The document provides detailed specifications and descriptions of various components and systems used in miniaturized fluorescence microscopy, particularly for deep-brain imaging. It includes information on different models of fluorescence microscope bodies, imaging cannulas, and associated accessories.

1. Product Specifications:

Fluorescence Microscope Bodies: Available in different models (S and L) with specifications such as mass, dimensions, frame rate, and field of view. The Model L features a 0.5 NA objective lens, while Model S relies on an external lens.
2-color Fluorescence Microscope Bodies: These bodies allow simultaneous imaging of two fluorophores using two CMOS sensors. They are optimized for specific imaging cannulas and surface imaging.
Twist-on efocus Fluorescence Microscope Body: Designed for larger brain areas, it offers a large field of view and electronic depth adjustment. It is compatible with Twist-on efocus Imaging Cannulas.
Twist-on efocus Optogenetically Synchronized Fluorescence Microscope Body: Combines optogenetic capabilities with fluorescence imaging, featuring a large field of view and electronic focus adjustment.

2. Imaging Cannulas:

Snap-in Imaging Cannula Model S and L: Used for different brain depths, with Model L featuring a gradient-index rod lens for deeper imaging.
Reduced Footprint Imaging Cannula Model L: Designed for stability with a smaller diameter for imaging specific brain areas.
2-channel Optogenetics and Imaging Cannula Model L: Features dual implants for imaging and optogenetic stimulation.
Imaging Cannula Model L with Prism: Allows imaging of sagittal-coronal plane sections, preserving brain tissue above the region of interest.

3. Ordering Information: Each product has specific ordering codes and options for customization, such as cable length, excitation wavelengths, and lens specifications.

4. Key Notes:

All microscope bodies and cannulas come with protective caps.
Electrical cables and optical fiber lengths are adjustable to fit specific requirements.
Protrusion adjustment rings are available for fine focusing and are provided with each cannula model.

Overview: The document provides detailed specifications and descriptions of various components and accessories used in miniaturized fluorescence microscopy, focusing on Twist-on Imaging Cannulas, Fluorescence Microscope Drivers, Accessories, and Fiber Photometry Systems.

Twist-on Imaging Cannulas: These are compatible with Twist-onefocus Fluorescence Microscope Bodies. The GRIN lens diameter can be either 500 µm or 1000 µm, affecting the field of view. The Imaging Cannula Model L with Prism allows imaging of sagittal-coronal plane sections, preserving the brain tissue above the region of interest. Specifications include GRIN diameter and penetration depth ranges.

Fluorescence Microscope Drivers: Two types of drivers are described: the basic driver for single-color fluorescence and a 2-color driver for controlling blue and yellow light sources. Both allow computer control and synchronization with external devices.

Accessories: Various accessories are detailed, including electrical cables with customizable jackets, microscope holders compatible with stereotaxic instruments, dummy microscopes for habituation, and snapping tools for easy detachment of microscope bodies. Protrusion Adjustment Rings are available for different observation depths.

Fiber Photometry Systems: These systems are used for measuring fluorescence in neuroscience applications. The document describes a 1-site system for GCaMP fluorescence and a system for dual-color measurements. Key components include LED drivers, fluorescence mini cubes, fiber-optic cannulas, and data acquisition consoles.

Key Specifications: The document includes tables with specifications for various components, such as GRIN lens diameters, penetration depths, and ordering codes for easy reference.

Overview: The document discusses the optimization of signal detection in Fluorescence Mini Cubes by integrating Doric Fluorescence Detectors and Built-in LED Optical Heads. This integration aims to minimize fiber optic connections and enhance performance.

Specifications:

Built-in Fluorescence Detector Head: Increases signal transmission by 30% due to proximity to the signal source and reduced optical connections. Each detector head is paired with a Fluorescence Detector Amplifier.
Built-in LED Optical Head: Eliminates the need for light source patch cords and includes an Intensity Adjustment Ring for precise light control, suitable for low-power experiments.
Ports: Ports for opsin activation/silencing have FC receptacles, and built-in devices can be replaced with FC Receptacles upon request.

Integrated Fluorescence Mini Cubes:

3-Port Cubes: Used for single excitation band fiber photometry measurements with customizable filters for GFP-like or RFP-like fluorophores.
4-Port Cubes: Include configurations for excitation, fluorescence, and opsin activation, suitable for GCaMP fluorescence measurements and red opsin activation.
5-Port Cubes: Allow for excitation and detection of two fluorophores and opsin activation.
6-Port Cubes: Designed for detecting fluorescence from two calcium indicators and GCaMP isosbestic excitation.
7-Port Cubes: Capable of separating three different fluorophores simultaneously.

Rotary Fluorescence Mini Cubes:

Designed for fluorescence recording of freely moving subjects, these cubes integrate LED light sources and detectors to enhance collection efficiency and reduce motion-related signal variation.
Available in configurations with 3, 4, and 6 ports, supporting various excitation and detection setups.

Bundle-imaging Fluorescence Mini Cubes:

These cubes facilitate fiber photometry on multiple sites or animals by bundling patch cords and using a camera for measurement.
Available in 4-port and 6-port configurations, supporting sequential detection and multiple fluorescence measurements.

Photodetectors:

Doric Fluorescence Detector: Features high gain and low noise, suitable for detecting signals in the sub-picowatt to nanowatt range, with options for AC/DC detection modes.
Newport Visible Femtowatt Photoreceiver Module: Offers high gain and sensitivity for detecting CW light signals, with an add-on fiber-optic adapter for improved coupling efficiency.

Overview: The document provides detailed technical specifications and ordering information for various photometry and electrophysiology equipment used in neuroscience research. It includes descriptions of photoreceiver modules, photosensor modules, power supplies, fiber photometry racks, behavioral tracking cameras, and optogenetically synchronized electrophysiology systems.

Photoreceiver and Photosensor Modules: The Newport Photoreceiver Module and Hamamatsu H10722-20 Photosensor Module are highlighted for their sensitivity in low light detection. The Hamamatsu module is compatible with specific cubes and requires a power supply model C10709. The document includes a table comparing the limit of detection for different photodetectors.

Fiber Photometry Accessories: Various racks and drivers are described for organizing and operating fiber photometry systems. The Fiber Photometry Rack for FMC5 and FMC7 are designed for different system complexities, while the Bundle-imaging Fiber Photometry Driver coordinates multiple devices.

Behavioral Tracking: The document details USB 3.0 and GigE Behavior Tracking Cameras, including specifications such as video formats, frame rates, and lens specifications. These cameras are used for high-speed video streaming and are synchronized with other devices using Doric Neuroscience Studio software.

Optogenetically Synchronized Electrophysiology (OSE): The document describes systems that integrate optogenetics with electrophysiological recordings. The Fiberless & Wireless (Fi-Wi) OSE System includes components like the opto-electric cannula, wireless headstage, and electrophysiology console. Specifications for headstages and cannulas are provided, emphasizing their customization for specific experiments.

Electrophysiology Console: This console manages communication between the computer and headstage, controlling recording parameters and LED stimulation sequences. It supports up to two headstages simultaneously and allows real-time data streaming and parameter adjustments.

Specifications: The document outlines the specifications of a system capable of handling up to two headstages simultaneously. It includes 4 digital input/output TTL channels, 4 analog output channels, digital communication via SPI and LVDS, and USB2 connectivity. The system is compatible with Doric Neuroscience Studio and includes all software updates.

Accessories: Several accessories are detailed, including the Fi-Wi Headstage Charger, Dummy Headstage, Test Cannula, and Cannula Implantation Holder. Each accessory has a specific function, such as recharging headstage batteries, simulating headstage weight, testing headstage functions, and securing cannulas during implantation.

Doric Neuroscience Studio: This software provides integrated control for devices used in neurophotonics experiments. It includes modules for light source control, behavior tracking, photometry, fluorescence microscopy, and electrophysiology. The software facilitates synchronization, data acquisition, and basic data analysis.

LED Illumination Accessories: Includes a Fan Power Adapter for LED drivers and an Optical Breadboard for mounting systems with Connectorized LEDs.

Rotary Joints Accessories: Various holders and adapters for rotary joints are listed, providing compatibility with different joint configurations.

Cannulas Accessories: Details on polyethylene tubing for opto-fluid cannulas and mating adapters are provided, including specifications and ordering codes.

Connectors and Dust Caps: Information on M3 connectors and dust caps for various receptacles is included, with options for titanium and peek plastic materials.

Cables and Other Accessories: Ordering codes for various cables and additional accessories like cleavers and fiber-optic swabs are provided.

Contact Information: The document concludes with contact details for Doric Lenses Inc., a provider of photonics solutions.

Catalog excerpts

Twist-on efocus Miniaturized Fluorescence Microscope

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Contents Light Generation & Control LED Illumination . . . . . . . . . . . . . . . . . . . . Laser Diode Illumination . . . . . . . . . . . . . . . Ce:YAG Fluorescent Illumination . . . . . . . . . . . Modulators . . . . . . . . . . . . . . . . . . . . . . . Beam Splitters/Combiners Doric Mini Cubes . . . . . . . . . . . . . . . . . . . Doric Micro Splitters . . . . . . . . . . . . . . . . . Doric Multiple Splitters/Combiners . . . . . . . . . Beam Modiﬁers Filtering . . . . . . . . . . . . . . . . . . . . . . . . . NA Converter . . . . . . . . . . . . . . . . . . . . . Rotary Joints Fiber-optic...

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Fiber Photometry Console . . . . . . . . . . . . . . . . . . . . . . . . . Connectorized Fluorescence Mini Cubes . . . . . . . . . . . . . . . . . Integrated Fluorescence Mini Cubes . . . . . . . . . . . . . . . . . . . Rotary Fluorescence Mini Cubes . . . . . . . . . . . . . . . . . . . . . . Bundle-imaging Fluorescence Mini Cubes . . . . . . . . . . . . . . . . Photodetectors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Fiber Photometry Accessories . . . . . . . . . . . . . . . . . . . . . . . Behavioral Tracking Behavior Tracking Cameras . . . . . . . . . . . . . . . . . ....

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Overview of Neuro-photonics products catalog Over the years, this catalog has grown beyond its optogenetics roots to become a reference for neuro-photonics products. Initially, it covered only the hardware that was used for light stimulation and/or control of cells marked with genetically encoded light-sensitive proteins. In these experiments, the light from a laser or an LED source is sent through an optical ﬁber to a slice of brain tissue, or to the brain of a head-ﬁxed or freely-moving animal. Overtime, this simple optical link has evolved into more complex circuitry, resembling the early...

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(Left) Optogenetic stimulation with a Laser Diode Fiber Light Source. (Right) Bilateral optogenetic stimulation with a Connectorized LED with Fiber-optic Rotary Joint.

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(Left) Dual optogenetic stimulation with a Laser Diode Fiber Light Source. (Right) 2-color optogenetic stimulation with a Ce:YAG + LED Fiber Light Source.

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(Left) Miniaturized Fluorescence Microscopy System used for calcium imaging with GCaMP6. (Right) Fiber Photometry System with a 4 port Integrated Fluorescence Mini Cube and a Fiber Photometry Console.

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(Left) Optogenetic stimulation and electrophysiology recordings with an Opto-electric Probe Tip. (Right) Optogenetic stimulation and ﬂuid delivery with a Mono Opto-ﬂuid Cannula

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Fiberless & Wireless Optogenetically Synchronized Electrophysiology System and Behavior Tracking Camera

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Light Generation & Control LED Illumination Light emitting diodes (LEDs) coupled in an optical ﬁber are suitable for neuroscience experiments which need to bring light into the brain. LED light allows to control the excitation, inhibition or signalling of speciﬁc cells in optogenetic experiments. The uniform illumination of an LED makes it the preferred light source for miniature ﬂuorescence microscopy and ﬁber photometry. Our compact Connectorized LEDs or multiple color combined LEDs are used with programmable LED Drivers. We also oﬀer LED Fiber Light Sources integrating 1, 2, or 4 independently...

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Light Generation & Control Table 1: Typical Connectorized LED Output Power vs Optical Fiber Core Diameter Overdrive @2000 mA (pulsed) TYPICAL OUTPUT POWER @1000 mA (mW)* The power is given for Connectorized LEDs and LEDs with Fiber-optic Rotary Joints (LEDFRJ)† . Contact us for power levels for other LED products. Connectorized LED male pinout power values taken at a maximum current of 1000 mA, except for 365, 385, 405 and 420 nm LEDs (500 mA). In overdrive mode, LED drivers can produce

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Light Generation & Control 13 Table 2: Connectorized LEDs Color Codes Central Wavelength (nm) ORDERING CODE: CLED LED color code (see Table 2) LED Drivers Doric programmable LED Drivers are available in 1-, 2-, and 4-channel versions. When connected to a Connectorized LED having an eprom memory, the LED Driver recognizes the LED wavelength and automatically sets the maximum current value. In stand-alone mode, all LED Drivers allow cw operation and external analog modulation through an input BNC connector for each channel. For each channel, there is also a current monitoring BNC output allowing...

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Light Generation & Control eliminating the need for a function generator. In low-duty cycle pulsed mode, the software allows to overdrive the LED sources if a higher power is needed. For multiple channel driver versions, each channel is controlled independently. Although not mandatory for LED sources, our LED Drivers come with a safety interlock connector and a main key switch. These safety features are of interest for UV and near infrared LEDs. Note: The renewed line of Doric LED Drivers has a new connector pinout that does not include pins for fan power. It is thus essential to use a Fan Power...

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Light Generation & Control Combined LEDs Doric Combined LEDs merge the light from multiple LEDs of diﬀerent colors into a single output connector by using a patent pending regular pentagon mirrors conﬁguration. The coupling eﬃciency for respective colors is near those of our Connectorized LEDs. Each LED of the Combined LEDs is driven independently via M8 cable when connected to any of our driver(s). Notes: • A compatible holder is included to secure the Combined LEDs. • Combined LEDs do not include the corresponding LED Driver. See Table 4 for available LED Driver models. • The renewed line of...

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Light Generation & Control Notes: • A compatible holder is included with the Connectorized LED + Fiber-optic Rotary Joint (Holder FRJ large; see Table 117). • An optional gimbal holder allows pivoting the rotary joint along two additional axes, further reducing the mechanical stress on the animal (GH FRJ; see Table 119). • A Connectorized LED with Fiber-optic Rotary Joint does not include the corresponding LED Driver. See Table 4 for available LED Driver models. ORDERING CODE: LEDFRJ LED color code (see Table 2) Combined LEDs with Fiber-optic Rotary Joint Combined LEDs with Fiber-optic Rotary...

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Hardware Catalog SFN2019

Hardware Catalog SFN2019

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