DUAL FIBER-OPTIC CANNULA
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Optogenetics catalog 7.5 - Fiber-optic Cannula Fiber-optic Cannula A fluid cannula is an assembly of a metal tube and a fluid tube receptacle, used for administering fluids when metal tube is inserted into the body. A venous cannula is inserted into a vein to obtain blood samples or to deliver medicines. The body of a cannula has a form that easily connects to or disconnects from the plastic tubing. The plastic tubing can be disconnected while the cannula remains attached to the body surface with the hollow needle (tube) inserted into the body for the later use. Similar to those fluid cannulas, biomedical and optogenetics applications need fiber-optic cannulas to introduce the laser or LED light into the body tissue. Mono fiber-optic cannula As an example, illuminating the neurons within the Rectangular mouse brain with the blue or orange light has become magnetic an essential tool for studying the processes within genetically modified photosensitive neurons. In early days of optogenetics, researchers used a fluid cannula to insert the optical fibers into the brain tissue, where the metal tube was guiding the fiber to the neurons. After the experiment, the optical fiber was removed from the cannula only to be reinserted later. The optical fiber removal and reentry could lead to infections and clogging of the fluid cannula. With some exceptions, the fiber-optic cannula is typically used without the metal tube of the fluid cannula. It consists of a fiber-optic ferrule with some sort of fiber-optic receptacle on one side and the implantable fiber protruding from the other side. When the fiber-optic cannula is fixed to the body Optic & Fluid Cannula - and the fiber implanted, the light can be delivered to the tissue and the fluorescence or scatter from the M3 tissue can be captured. In these experiments, it is imperative that the connection between the delivery fiber and the cannula is light, small and simple to connect and disconnect. For a mono fiber delivery, the connection between the ferrules of the light delivery fiber patch cord and the fiber-optic cannula is achieved, in its simplest form, via

Optogenetics catalog 7.5 - Fiber-optic Cannula fiber-optic sleeve. The connector type connection is preferred but it is not always applicable. In some optogenetics experiments it is necessary to introduce two or more implantable fibers within a small, precise distance. Those applications call for the dual fiber-optic cannula that is easily connected to the matching delivery fibers. The concept of fiber-optic cannulas with different optical fibers, receptacle types and fiber terminations is bound to be further fragmented. So far we carry Mono fiber cannulas, Dual fiber cannulas, Two ferrules...

Optogenetics catalog 7.5 - Fiber-optic Cannula Table 8: Plastic optical fibers Core Outer diameter Numerical Aperture Buffer color Fiber-optic code Table 9: Fiber-optic termination codes for cannulas Termination Description code FLT Standard angles: 45°; 60° Other angles on request (max 60°) Standard angles: 45°; 60° Other angles on request (max 60°) Rounded tip thickness: ~ 0.1x to 0.2x core diameter Standard angles: 45°; 60° Other angles on request (max 60°) Note: Axx, Bxx, Cxx and Rxx are offered to facilitate the insertion of the fiber-optic in the tissue. However, they have little...

Optogenetics catalog 7.5 - Fiber-optic Cannula Mono Fiber-optic Cannula The mono fiber-optic cannula is an assembly of a bare optical fiber, a fiber ferrule and a receptacle or a sleeve. One side of the ferrule is polished while the implantable part of the fiber protrudes from the opposite end of the ferrule. The ferrule is placed within receptacle or sleeve to allow connecting to the fiber-optic patch cord. The protruding fiber can be implanted into the body while the ferrule or the receptacle is attached to the skin. When the cannula is connected with the patch cord, it is possible to...

Optogenetics catalog 7.5 - Fiber-optic Cannula Table 10: Receptacle codes for mono fiber-optic cannula Description Zirconia ferrule OD 1.25mm Receptacle with M2 thread Titanium Receptacle with M3 thread Titanium Receptacle with M3 thread Peek plastic Rectangular Magnetic Receptacle Titanium See receptacle section for details on mass and dimensions.

Optogenetics catalog 7.5 - Fiber-optic Cannula Dual Fiber-optic Cannula A dual fiber-optic cannula provides two implantable fibers at a precise distance within a single ferrule. The tolerance on the protrusion for each fiber is less than 0.1 mm. These cannulas are perfectly suited for the applicationsGuiding where two brain centers close to each hole other are simultaneously optically stimulated or controlled. Flange The positioning of one mono fiber cannula Ferrule Fiberat a time with the stereotaxic equipment optics has greater likelihood of 3D positioning errors (lateral and depth)....

Optogenetics catalog 7.5 - Fiber-optic Cannula Table 11: Receptacle codes for dual fiber cannula “Pitch” = Distance between the fibers (mm) 0.7 Receptacle code Select distance (x) in 0.7 mm – 1.7 mm range

Optogenetics catalog 7.5 - Fiber-optic Cannula Two Ferrules Cannula The two ferrules cannula provides two implantable fibers, each within its own ferrule, at a precise distance exceeding 1.7 mm. The tolerance on the protrusion for each fiber is less than 0.1 mm. These cannulas are perfectly suited for the applications where two brain centers at a distance larger than 1.7 mm from each other are optically stimulated or controlled. The positioning of one mono fiber cannula at a time with the stereotaxic equipment has greater likelihood of 3D positioning errors (lateral and depth). With two...

Cytogenetics catalog 7.5 - Fiber-optic Cannula 70 Table 12: Termination codes for two ferrules cannula

Optogenetics catalog 7.5 - Fiber-optic Cannula Fiber-optic Cannula Arrays Basically this product can be described as a loose fiber optic bundle with FC/PC connectors on loose end and V-groove based fiber-optic cannula array on the other end. ORDERING CODE: FCA1x8_□□□/□□□-□□□_□□□_□□□_□□□_□□□ Fiber-optic code See Table 7 and Table 8 Protrusion of fiber “L”(mm) Fiber-optic pitch (um): See Table 12 Overall fiber length (mm) Termination Code for Multiple connectors side See Table 2 for available codes