PTM Capsule Filters PTFE Membrane Solvent Filtration Tank Vent Filters Pharmaceutical grade TM capsules are manufactured for the critical needs of the pharmaceutical industry. Made with highly hydrophobic polytetrafluoroethylene (PTFE) membrane, these capsules are used for filtration of non-aqueous liquids, aggressive solvents, compressed gases, and as vent filters. Each module is individually tested using the water intrusion method before it is released from manufacture. The capsule media surface area, filter core design, pleat configuration and pleat packing density have been optimized to provide increased life resulting in lower filtration operating costs. Optimized for maximum filter life Designed for filtration of air and process gases V ent filtration for the protection of tank contents Final filtration of solvents, alcohols and other non-aqueous liquids PTM Capsule Filters - Filtration Area Capsule Length PTFE Membrane Flow Rate / Filtration Area The following table represents typical air and water flow at a one psi (69 mbar) pressure differential across a single 2 inch capsule with 1.0 ft ² (930 cm²) of media with 1/2” FNPT ports. The liquid test fluid is water at ambient temperature. The gas test fluid is compressed air at ambient temperature. Higher pressure drops are acceptable, but as flows increase the pressure drop of the housing becomes more apparent. Air/Gas Flow Rates Liquid Flow Rates Construction Materials Maximum Operating Parameters Liquid Operational Pressure Filtration Media PTFE Membrane Gases Operational Pressure Media Support Operating Temperature Center Core Outer Support Cage Sealing Method Thermal Bonding Forward Differential Pressure 50 psid (3.4 bard) at 20 °C (68 °F) Reverse Differential Pressure Recommended Changeout Pressure Pharmaceutical Grade

Integrity Test Specifications 60/40 IPA/water wetted membrane PTM capsules are validated using test procedures that comply with the intent of both ASTM F 838-05 and HIMA protocols for the determination of bacterial retention. The challenge level is 107 organisms per cm2 of filter media; 0.22 μm challenged with Brevundimonas diminuta; 0.45 μm challenged with Serratia marcescens. Pore Size Bubble Point Critical Process Filtration can provide validation assistance. Quality Assurance and Standards The materials used to construct pharmaceutical grade PTM capsule filters are non-toxic and meet the...