PPD Cartridge Filters Pleated Polypropylene Depth Media Applications Biologicals Buffers and Other Media Dimensions Length Outside Diameter Filtration Area PPD Depth Filter Cartridges are designed to be used as pre-filters in critical pharmaceutical systems. Special attention was given in the design of these cartridges to ensure long life as well as superior retention. PPD Depth Filter Cartridges are rated at 99.9% efficiencies at the rated pore size and have been flushed with high purity water (18+ megohm-cm) to remove any manufacturing debris and ensure particle-free filtrate. Construction Materials 5.8 ft2 (0.54 m2) per 10 in. length (Average - area varies with media thickness and porosity) Maximum Operating Parameters Differential Pressure • Forward Operating Temperature Recommended Changeout Pressure 82 °C (180 °F) at 10 psid (0.69 bard) in water 35 psid (2.4 bard) Filtration Media Pleated Polypropylene Depth Media Media Support 90 °C (194 °F), 30 minutes, multiple cycles, max 3 psid forward flow Center Core Outer Support Cage In-line Steam Sealing Method Thermal Bonding Buna, Viton®, EP, Silicone, Teflon® Encapsulated Silicone, Teflon Encapsulated Viton Integrity Test Information All PPD cartridge filter modules are factory tested for integrity before shipment. Field duplication of these tests is not practical because of the absence of commercial portable testing equipment. For all elevated temperature procedures above, a stainless steel support ring is required. Chemical Sanitization Performed using industry-standard concentrations of hydrogen peroxide, paracetic acid, sodium hypochlorite and other selected chemicals. Total Performance Critical Process Filtration, Inc. is a vertically integrated manufacturer of filtration products to industries in which filtration is considered a critical part of the manufacturing process. We supply a complete line of products and services to help you cost-effectively satisfy all your filtration requirements from a single source. Pharmaceutical Grade

The materials used to construct pharmaceutical-grade PD cartridge filters are non-toxic and meet the requirements for the MEM Elution Cytotoxicity Test and the requirements for Biological Reactivity Tests in the current version of the United States Pharmacopeia (USP) for Class VI - 121 °C Plastics. PPD cartridge filters comply with Title 21 CFR sections 210.3 (b)(6) and 211.72, for non-fiber-releasing filters. The levels of bacterial endotoxins in aqueous extracts from pharmaceutical-grade cartridge filters are below current USP limits as specified for water for injection. PPD cartridges are...