BTM Capsule Filters PTFE Membrane Solvent Filtration Non-Aqueous Solutions Tank Vents The capsule media surface area, filter core design, pleat configuration and pleat packing density have been optimized to provide increased life resulting in lower filtration operating costs. Optimized for maximum filter life F iltration of air and process gases V ent filtration for the protection of tank contents F iltration of solvents, alcohols and other non-aqueous liquids BTM Capsule Filters - Filtration Area Capsule Length PTFE Membrane Flow Rate / Filtration Area The following table represents typical air and water flow at a one psi (69 mbar) pressure differential across a single 2 inch capsule with 1.0 ft ² (930 cm²) of media with 1/2” FNPT ports. The liquid test fluid is water at ambient temperature. The gas test fluid is compressed air at ambient temperature. Higher pressure drops are acceptable, but as flows increase the pressure drop of the housing becomes more apparent. Air/Gas Flow Rates Liquid Flow Rates Construction Materials Maximum Operating Parameters Liquid Operational Pressure Filtration Media PTFE Membrane Gases Operational Pressure Media Support Operating Temperature Center Core Outer Support Cage Sealing Method Thermal Bonding Forward Differential Pressure 50 psid (3.4 bard) at 20 °C (68 °F) Reverse Differential Pressure Recommended Changeout Pressure Biopharmaceutical Grade Biopharmaceutical grade TM capsules are manufactured for critical applications in biopharmaceutical processing. Made with highly hydrophobic polytetrafluoroethylene (PTFE) membrane, these capsules are used for filtration of fermentation air, solvents and alcohols, compressed gases, and as vent filters. Each module is individually tested using the water intrusion method before it is released from manufacture.

Integrity Test Specifications Biopharmaceutical grade TM capsules are validated using test procedures based on ASTM Method F838-05 and HIMA protocols. The challenge level is 107 organisms per cm2 of filter media: (per 1.0 ft2 (930 cm2) 60/40 IPA/water wetted membrane) Pore Size Bubble Point 21 psig (1.45 barg) 15 psig (1.0 barg) 9 psig (621 mbarg) 6 psig (414 mbarg) 0.22 μm challenged with Brevundimonas diminuta; 0.45 μm challenged with Serratia marcescens; Critical Process Filtration can provide validation assistance. The materials used to construct biopharmaceutical grade BTM capsule filters...