Biopharm PES Capsules


Catalog excerpts

Biopharm PES Capsules - 1

BPS Capsule Filters PES Membrane Applications Buffers and Feedstocks WFI Water Polyethersulfone is particularly suited for the filtration of products that contain elements that can adsorb to the media, such as preservatives and proteins. The lower binding characteristics of PES make it a good choice for filtration of valuable protein solutions such as vaccines and other biologicals. Excellent flow rates with high throughput D esigned for minimal leachables and extractables Low adsorption of proteins and preservatives Flow Rate / Filtration Area The following table represents typical water flow at a one psi (69 mbar) pressure differential across a single 2 inch capsule with 1.0 ft² (930 cm²) of media with 1/2” FNPT ports. The test fluid is water at ambient temperature. Higher pressure drops are acceptable, but as flows increase the pressure drop of the housing becomes more apparent. Pore Size * For approximate flow rates for 5” through 30” capsules, refer to the appropriate cartridge data sheet BPS Capsule Filters - Filtration Area Media PES Membrane Maximum Operating Parameters Liquid Operational Pressure Filtration Media Gases Operational Pressure Operating Temperature Media Support Forward Differential Pressure 50 psid (3.4 bard) at 20 °C (68 °F) Center Core Reverse Differential Pressure Outer Support Cage Sealing Method Thermal Bonding Recommended Changeout Pressure Biopharmaceutical Grade Biopharmaceutical grade PS capsules are hydrophilic and manufactured with the highest quality asymmetric polyethersulfone (PES) membrane. PES membrane exhibits excellent flow rates with high throughput. BPS capsule filters are used for bioburden reduction applications in the biologicals industry. Specific applications for BPS capsule filters are bacteria removal in buffers, USP Water for Injection (WFI), SVPs, LVPs and other biological products. The filter elements are 100% integrity tested during production. Validated for use in multiple biopharmaceutical applications Construction Materials

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Biopharm PES Capsules - 2

Integrity Test Specifications Pore Size Biopharmaceutical grade filters typically exhibit low levels of non-volatile residues. Max Diffusion Rate (cc/min -water wetted membrane) Quality Assurance and Standards Critical Process Filtration uses state of the art computer controlled equipment to consistently produce high quality products as well as significantly reduce hand operations that can compromise quality. All manufacturing and testing is continuously monitored in real time so that data can be quickly and easily analyzed to facilitate improvements in both quality and cost. The Critical...

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