Corning® Microplates Right microplate. Right surface. Right now.

o o oo oo oooo oooo oooooo oooooo oooooo oooooo oooooo At Corning we are committed to enhancing cell culture and accelerating discovery through innovative products and dedicated service. We strive to make drug discovery more efficient and convenient by offering versatile choice, outstanding quality, consistency, and value. Corning offers a broad portfolio of microplates designed for use with adherent cell assays, a wide selection of surface treatments, to include biological ECM coatings (Corning BioCoat™) and synthetic surface coatings (Corning PureCoat™), as well as tissue cultured-treated surfaces...

A legacy of innovative surfaces for enhanced confidence in results and consistency We offer a unique line of tissue culture vessels coated with a variety of extracellular matrix proteins and attachment factors: Corning BioCoat™ cultureware. Today, Corning continues to innovate with Corning PureCoat™, a one-of-a-kind family of animal-free and chemically-defined surfaces. Corning understands the importance of consistency and the need for reproducible results. Through proprietary manufacturing and exacting quality control, we are able to assure performance of our products as well as consistency...

MICROPLATE SELECTION GUIDE BY SURFACE, FORMAT, AND PLATE COLOR Services • Dedicated technical support to assist in custom coating, bar-coding, product/surface recommendations, or troubleshooting • Personalized attention with custom coatings and bar-coding service • Custom ordering with lid of choice available COLOR KEY FOR PLATE COLORSDETECTION METHOD PLATE COLOR RECOMMENDATION Colorimetric 0 Clear O Black/Clear Luminescence O White

SURFACE SELECTION GUIDE BY ASSAY TYPE ASSAY TYPE BIOLOGICAL ECM-COATED Corning BioCoat™ SYNTHETIC TISSUE CULTURE-Corning PureCoat™ TREATED Ion channel/Calcium flux (FLIPR®) GPCR (Act/Inact) Cell cytoxicity Cell proliferation Cell adhesion Differentiation (primary cells) Cell migration Reporter gene Neurite outgrowth ooooooooooo 'OOOOOOOOOOO ooooooooooo ooooooooooo 'OOOOOOOOOOO 'OOOOOOOOOOO 'OOOOOOOOOOO 'OOOOOOOOOOO

SURFACE SELECTION GUIDE BY CELL TYPE Note: The above table shows only a representative list of cell types, for additional information please contact Technical Support at 800.492.1110.

BIOCOATCorning® BioCoat™: Biological ECM-Coated. Corning BioCoat microplates are offered in a variety of surface treatments to provide enhanced cell attachment and growth Corning BioCoat microplates have been further enhanced (versus TC) with biological coatings of highly purified extracellular matrix (ECM) proteins for the cell culture of more complex cell models, to include transformed cell lines, transfected cells, as well as a variety of primary and stem cells. Corning BioCoat microplates are coated in a highly controlled, asceptic manufacturing environment to ensure lot-to-lot consistency,...

Corning® BioCoat™ Poly-Lysine microplates Poly-D-Lysine (PDL) is a synthetic polymer that enhances cell adhesion and protein absorption by altering surface charges on the culture substrate. As PDL are synthetic molecules, they do not introduce impurities carried by natural polymers. Many transfected cells, but also neuronal cell lines, primary neurons and glial cells have been cultured successfully on PDL. HEK-293 cells on Corning BioCoat PDL Corning BioCoat Collagen I microplates Collagen I, found in most tissues and organs, is most plentiful in dermis, tendon, and bone. It is an integral part...

PURECOATCorning® PureCoat™: Chemically-Defined (Synthetic) Coated. Defined and synthetic Corning PureCoat surface for robust, consistent and reproducible assays Corning PureCoat microplates have been precoated with chemically-defined (synthetic) attachment factors to provide an enhanced surface which is appropriate for a broad range of cell types (primary cells and transformed cell lines) and applications, but is ideal for applications requiring a more defined cell culture environment (serum-free or low serum-containing cultures). Corning PureCoat microplates are preferred in a range of screening...

Enhanced Cell Attachment and Consistency with Corning® PureCoat™ Amine. Panel A Competitor A Corning PureCoat amine AFTER WASH BEFORE WASH Enhanced attachment of EcoPack™2-293 cells, a viral packaging cell line on Corning PureCoat amine. Cells were seeded onto 384 or 1536 well black/clear Corning PureCoat amine, TC-treated, or Competitor A plates at 10,000 cells/well and 2,250 cells/well, respectively, and grown under serum-free conditions for 20-24 hours. The cells were then washed (on a Skatron EMBLA washer) two times with HBSS containing 10 mM Hepes, loaded with calcein AM for 1 hour and read...

Falcon tissue culture-treated The Falcon brand is the leader in high-quality cultureware building on a heritage of proven reliability and consistency for confident cell culture conditions to assure dependable research outcomes. The Falcon tissue culture-treated (TC) surface is a permanently hydrophilic surface which is produced via a unique vacuum-gas plasma process in a strictly controlled, closed environment, ensuring a highly consistent culture surface which is suitable for a broad range of cell types. Falcon and Corning Primaria™ surfaces support a range of applications and many important...

Corning® PrimariaTM Corning Primaria supports neuronal cells, primary cells, endothelial, and tumor cells which may have difficulty attaching to or differentiate poorly on traditional TC surfaces. This surface features a unique mixture of negatively charged (oxygen containing) and, positively charged (nitrogen containing) functional groups on the polystyrene. The surface consistency of each lot is confirmed by electron spectroscopy chemical analysis (ESCA). When epithelial bladder cancer cells (KU19-19) are cultured on Corning Primaria, cells nicely attach and spread on this surface. After 4...