Optogenetics Solutions data sheet
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Data sheet Cobolt Optogenetics Laser Solution Cobolt offers a range of high performance, reliable and user friendly laser assemblies specially tailored for advanced Optogenetics research. The laser assemblies have been developed in close collaboration with leading Optogenetics research laboratories and offer experiment-ready solutions for configurable solutions for channelrhodopsin activation and halorhodopsin inhibition. Cobolt’s Optogenetics solutions include single-line lasers with stable and efficient coupling into multi-mode fibers, two lasers on one platform launched into one common fiber coupler or two lasers sitting side by side launched into one fiber each, suitable for 2-into-1 coupling using e.g. fused fibers. The lasers are available at various wavelengths matching the sensitivity peaks of the commonly used rhodopsins, with adjustable optical output power up to over 100 mW and fast high aspect ratio modulation with perfect pulse control. Each configuration starts with a highly reliable and very stable Cobolt laser. The Cobolt 06-01 Series lasers are ultra-compact plug & play modulatable lasers that can be directly modulated and feature precision electronics. The Cobolt 06-MLD 473 nm is the preferred laser for optogenetics. The Cobolt 04-01 Series of diode-pumped solid-state (DPSS) lasers enables laser excitation at wavelengths not available in the Cobolt 06-01 Series lasers, for example 594 nm. Configurations described in this document include single lasers or two lasers combined into a single multi-mode fiber (MM), lasers with or without intensity modulation capability and stand-alone lasers or assemblies with fiber couplers. To each fiber-coupled system, a MM fiber (with 50-200μm core diameter) of your choice can be easily attached. All packages offer full control over the pulse generation, perfect pulse-to-pulse stability, high extinction ratio and fiber coupling efficiencies of > 80%. Typical laser pulse train with sub-microsecond pulses Pulse graph of a Cobolt Mambo™ 594nm laser with AOM modulation. Pulse graph of a Cobolt 06-MLD 473nm laser with direct modulation. Cobolt AB | Solna, Sweden | PHONE +46 8 545 912 30 | FA X +46 8 545 912 31 | E-MAIL info@cobolt.se | www.cobolt.se Copyright ®Cobolt AB. All rights reserved June 2

a HUBNER Group company 3. Wavelengths available in Cobolt Modulated DPSS laser package: 594 nm Cobolt AB | Solna, Sweden | PHONE +46 8 545 912 30 | FAX +46 8 545 912 31 | Copyright ®Cobolt AB. All rights reserved June 2016

a HUBNER Group company Cobolt AB | Solna, Sweden | PHONE +46 8 545 912 30 | FAX +46 8 545 912 31 | Copyright ®Cobolt AB. All rights reserved June 2016 Input modulation signal req.: TTL 0-5V (to female SMA connector)

a HUBNER Group company Cobolt AB | Solna, Sweden | PHONE +46 8 545 912 30 | FAX +46 8 545 912 31 | Copyright ®Cobolt AB. All rights reserved June 2016 Input modulation signal req.: TTL 0-5V (to female SMA connector) FC/PC connector available upon request

a HUBNER Group company Cobolt AB | Solna, Sweden | PHONE +46 8 545 912 30 | FAX +46 8 545 912 31 | Copyright ®Cobolt AB. All rights reserved June 2016 Input modulation signal req.: TTL 0-5V (to female SMA connector)

a HUBNER Group company Cobolt AB | Solna, Sweden | PHONE +46 8 545 912 30 | FAX +46 8 545 912 31 | Copyright ®Cobolt AB. All rights reserved June 2016 Input modulation signal req.: 3-5V=On, 0-2V=OFF (to femal D-Sub 7W2)

a HUBNER Group company Cobolt AB | Solna, Sweden | PHONE +46 8 545 912 30 | FAX +46 8 545 912 31 | Copyright ®Cobolt AB. All rights reserved June 2016 Input modulation signal req.: TTL 0-5 V