TRS100 - Quantitative Pharmaceutical Analysis System

Streamlined Quality Control ... TEST HUNDREDS of intact tablets or capsules in minutes QUANTIFY API s and excipients in a single measurement REDUCE COSTS - No sample preparation, consumables or skilled testing resource REGULATORY - APPROVED METHODS for Content Uniformity, Assay and ID TRS100 for Quality Control and Development The TRS100™ is ideal for fast assay of tablets, capsules and other dosage forms. Transmission Raman Spectroscopy, Cobalt’s transmission Raman technology enables simple method-development unlike near-infrared spectroscopy, is not an absorption technique. This means TRS can...

Content Uniformity • Assay • ID • Polymorph Quantification • Formulation Development Coated Tablets Well Plates Analyse up to 300 samples on a single tray • Flexible sample prese

Transform your End-Product Testing Content Uniformity, Assay and ID – Faster, Leaner, Lower Cost TRS is a proven alternative to wet-chemistry analytical methods, needs no consumables or solvents and no preparative chemical skills. A single TRS100 CU test can often be completed in around 15 minutes, which enables a high throughput for QC testing and low resource usage compared to traditional HPLC methods. Calibration Standard TOTAL TIME AND RESOURCE FOR 8 BATCH CAMPAIGN: TRS METHOD • 120 minutes - 15 minutes per batch - Automated report TOTAL TIME AND RESOURCE FOR 8 BATCH CAMPAIGN: High Throughput...

Method Development Spectroscopic techniques, such as near infrared spectroscopy, can be challenging for quantitative method development. TRS has several advantages over other techniques: • Rich spectral features with high chemical specificity • Fast method development to ICH and pharmacopoeial standards • Development typically uses a lean calibration design of experiments (DoE) Regulatory Approvals CU, assay and ID methods are approved for releasing commercial batches of products using the TRS100. • Regulatory approvals achieved following International Committee on Harmonization (ICH)1 and spectroscopy...

Quantitative Pharmaceutical Analysis TRS100 Compliance Designed exclusively for quality control, analysis and testing in pharmaceutical manufacturing, working to the industry’s strict regulatory requirements. Integrated sample-handling for minimal operator interaction. Automatic calibration using NIST and ASTM-approved standards. Meets relevant USP, EP and 21 CFR part 11 requirements. • 21 CFR Part 11 compliant • Meets relevant USP and EP guidance Software • Requires minimum of Windows 7 Pro OS • Supplied with Cobalt’s ContentQC™ analysis and management software • Integrated Eigenvector Solo...