rapifleX™ Designed for Molecules that Matter. Innovation with Integrity MALDI TOF/TOF

The first MALDI-TOF/TOF that adapts to your needs. The rapifleX is the most advanced MALDI TOF/TOF system on the market today and it is also the most adaptable. Whether you are looking at top-down sequencing for Biotherapeutics and Biosimilars, glycan structure analysis and confirmation, and localization of disulfide/ trisulfide bond determination and scrambling analysis, the rapifleX is the best instrument for the job. The system combines state-of-the-art technology with advanced informatics into a system that gives you speed, robustness, versatility and confidence. Dr. Julian D. Langer, MPI...

MALDI-TOF/TOF for Applications that Matter Bruker has a long history of helping life scientists meet their toughest laboratory challenges. We provide the innovative MALDI TOF and MALDI TOF/TOF mass spectrometry systems that you rely on to accelerate your research. The rapifleX is the latest example of Bruker’s dedication to developing and delivering innovative MALDI-TOF analysis technologies. Top-Down Sequencing Unprecedented speed of analysis with 10 kHz laser reduces costs per sample. It enables time critical applications and faster decision making processes. The Bruker rapifleX platform offers...

Designed for your needs The first MALDI TOF/TOF that adapts to your needs Our passion is mass spectrometry. With the rapifleX series our engineers and developers have created the first MALDI–TOF/TOF system that now adapts to the analytical question at hand - automatically. The adaptable ion optics and class leading laser technology provide the best data quality, regardless of the acquisition mode or mass range. With speed in mind, we redesigned the heart of the rapifleX MALDI Imaging solution to work up to 20 times faster than traditional MALDI-TOF systems to meet the increasing requirements...

Speed - 10 kHz scanning smartbeam 3D laser for highest throughput – 5-20 x increase in speed Robustness - User removable ion source for easy cleaning, designed for maximum uptime in 24/7 operations Confidence - on optics adapt to application I - Three-stage reflector: No compromise, maximum resolution for full molecular weight range - Removable MS/MS ion optics for maximized sensitivity for MS analysis - S/MS mass range up to 8 kDa for large M peptides such as glycopeptides, di/trisulfide peptides and difficult non-tryptic peptides - recursor ion selector resolution increased to P 1000 – for...

Fast and robust tissue imaging The rapifleX MALDI tissuetyper is the complete solution for MALDI imaging. • astest acquisition with up to 50 pixel/second F • Superior image quality • Integration of histology • omprehensive software for the interpretation C of large tissue-based biomarker studies Proteins in sagittal rat brain section measured at 30 μm pixel size, ~150000 pixel. Identify biomarkers directly from tissue Tryptic peptide directly identified from tissue Even from complex matrices, high quality MS/MS spectra can be acquired and identified. The imageIDTM workflow combines tryptic digest...

Accelerating drug discovery and screening The new rapifleX MALDI PharmaPulse is the first mass spectrometer to offer the speed, specificity and robustness required for large primary screens in drug discovery: • abel-free ultra-high throughput screening L (uHTS) for biochemical assays • abel-free detection accelerates and simplifies L assay development and avoids interferences from artifacts • he integrated automation solution can process T 1536 HTS MALDI plates in less than 8 minutes • p to 100 times less solvent than multi-plexed U LC/SPE-MS systems • o need for SPE cartridges or HPLC columns...

rapifleX™ Designed for Molecules that Matter. For research use only. Not for use in diagnostic procedures. Bruker Daltonik GmbH Bremen · Germany Phone +49 (0)421-2205-0 Fax +49 (0)421-2205-103 [email protected] - www.bruker.com Scan the QR-Code for more Details to change specifications without notice. © BDAL 05-2016, 1844695 Dr. Matthias Trost, Programme Leader & Head of Proteomics MRC Protein Phosphorylation & Ubiquitylation Unit University of Dundee The rapifleX’s novel laser technology and an improved digitizer provide massive increases in speed and signal-to-noise compared to previous...