micrOTOF-Q III The bench-mark in accurate mass LC-MS/MS Innovation with Integrity

The Advantage of Confidence in Routine The micrOTOF-Q range is widely acknowledged in setting standards in performance and reliability by which all other accurate mass ESI mass spectrometers are judged. micrOTOF-Q III demonstrates the best performance standard in its class: • 20,000 full sensitivity resolution • Low picogram sensitivity • 2 ppm mass accuracy Each performance parameter whether it is mass accuracy, resolution, or sensitivity is top in its class. Uniquely in the market, micrOTOF-Q III makes no compromise in delivering the best - all parameters are simultaneously delivered for fullest...

• Your Partner in Innovative Chemistry Chemical formula generation Compass OpenAccess™ provides an automated walk-up LC-MS system for chemical formula generation, molecular formula confirmation and generic LC-MS measurements. This client-server based software supports LC-MS workflows especially for chemists in laboratories with various levels of instrumental analy- The GC-APCI source enables the combination of LC-QTOF MS with both provides exact mass accuracy and resol- ving power to expand the horizon for GC-MS based analyses. Data acquisition rates of 20Hz and faster are manda- tory for typical...

SmartFormula determination Three dimensions of information simultaneously raise your analytical tasks to unrivaled heights of confidence: Mass Accuracy several ppm accuracy plus Chemical Expertise additional confidence 14 8 Lycopsamine 6 Heliotrine-N-oxide Senkirkine-N-oxide 1 Senecionine-N-oxide 4 Seneciphylline-N-oxide 3 Lycopsamine-N-oxide High resolution chromatogram (hrXIC) identifying Pyrrolizidin-Alkaloides 200 ppb each in honey. Cmpd. Label S/N Monocrotaline 3422.4 Monocrotaline-N-oxide 469.9 Heliotrine-N-oxide 3670.0 Lycopsamine 5530.5 Lycopsamine-N-oxide 929.6 Retrorsine 13424.3 Senkirkine-N-oxide...

Top-Down Analysis of Intact Proteins and Antibodies Intact protein mass resolution measured spectrum, ∆ m = 1.3 ppm simulated spectrum; R=20,000 Ribonuclease B. A spectrum of the intact protein acquired with the micrOTOF-Q III. The mass difference to the calcu­ated mass is l only 1.3 ppm. A resolution of > 20,000 FWHM is achieved. BioPharma Compass results Automated analysis of monoclonal antibodies Result view of the intact mass workflow for identity testing of discovery mAbs. The identity of 54 different antibodies coming out of discovery are confirmed here. Color coding defined by user. Shown...

Technical Specifications Best in its class performance Proven micrOTOF-Q technology Class-leading combination of mass accuracy, resolution and sensitivity without compromise SmartFormula3D, the unique combination of accurate mass and true isotopic pattern of both, parent and fragment ions Wide dynamic range for ultra-stable accurate mass High-transmission dual ion funnel Q-q-front end Dimensions 640 x 949 x 1320 mm, weight 160 kg Source options APCI atmospheric pressure chemical ionization source APPI atmospheric pressure photo ionization source Direct probe option Direct GC coupling CryoSpray...