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Brochure micrOTOF II

Brochure micrOTOF II
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Bruker Daltonics The Powerful, Flexible Analysis Solution >

Being fully furnished with convincing mass accuracy, a high dynamic range and speed of analysis, micrOTOFII is the first choice for: Molecular Formula Verification De novo Formula Generation Multi-Target Screening Biomarker Discovery Intact Protein Analysis > Highest flexibility Significance in biomarker profiling The micrOTOF II is the first high resolution TOF-MS which can be used in combination with GC and LC, providing unequalled flexibility with remarkable mass accuracy. Metabolic profiling is a key technology in the study of drug efficacy, toxicology or clinical biomarkers....

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# possible formulae Mass accuracy > plus Chemical expertise additional confidence > plus SmartFormula (mass accuracy + TIP) sub-ppm confidence > De novo sum formula generation Detection of C > 21 H > 24 ClFNO > 2 Haloperidol with SmartFormula: The correct formula has the best Sigma-ranking (isotope pattern matching factor). Top spectrum: Measured, lower spectrum: Calculated theoretical isotopic distribution. >

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mass accuracy over intensity mass accuracy over time mass accuracy over mass range ֢ɤ 2mDa are gene- rated in a single experiment for >200 compounds2. A stability of <1mDa is achieved over time of experiment ID of unknowns Retrospective in silico screening for new or unexpected compounds is possible because, unlike in triple-quad based MRM methods, the full scan information content in addition to the target library specific information is retained. Read more: Application Note ET-12. Intra-spectra dynamic range Quantitative and qualitative analysis for forensics, doping control, and residue...

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Worldleading combination of mass accuracy, resolution, and sensitivity SmartFormula is the unique combination of accurate mass with True Isotopic Pattern (TIP) Automated determination of elemental composition, the formula finderӔ Footprint 640 x 640 mm, height 1220 mm, weight 130 kg > Mass range 50 20,000 m/z Mass resolution 16,500 FWHM with micrOTOF focus Mass accuracy of < 1-2 ppm (RMS) error with internal calibration Mass Stability & Dynamic Range proven by better than 2mDa hrEICs (high resolution Extracted Ion Chromatograms) Sub-ppm confidence by application of SmartFormula algorithm...

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