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PILOT AND IDUSTRIAL FERMENTERS BRS BIOTECH

PILOT AND IDUSTRIAL FERMENTERS BRS BIOTECH

PILOT AND IDUSTRIAL FERMENTERS BRS BIOTECH

Product catalog summary
Pilot and Industrial Fermenters Overview
BRS Biotech offers pilot and industrial scale fermenters designed for upscaling processes in biotech and pharmaceutical industries. These units are available as stand-alone or fully equipped lines.

Features
  • Volume range: 15 to 15,000 liters.
  • Platform-mounted with modular construction for easy maintenance and operation.
  • Separate cabinet for power, measurement, and control tools, allowing customization.

Applications
  • Agricultural and veterinary chemical production.
  • Pharmaceutical production compliant with GMP and FDA standards.
  • Biotech processes involving enzymes, bacteria, fungi, and algae.
  • Scale-up studies and process optimization.

Technical Specifications
  • Vessel: Design pressure of 3 bars, operating temperature range from +8°C to +60°C, with options for higher pressure and temperature.
  • Aeration System: Includes rotameter, exhaust gas heater, and sterile filters.
  • Agitation: Speed range of 40-800 rpm, with options for different seals and impeller types.
  • Lid Lifting System: Electrical system available for fermenters under 1000 liters.
  • Temperature Control: Automatic sterilization and temperature maintenance features.
  • Defoaming Control: Includes sensor and peristaltic pump for solution dosing.
  • pH and DO Control: Digital sensors with automatic adjustment and control options.
  • Pressure Measurement and Control: Includes sensors and safety valves.

Main Functions of Control Program
  • Three access levels for parameter settings and status display.
  • Data exportation in Excel format.
  • Remote operation option available.

Ports and Sampling System
  • Customizable ports for various sensors and sampling needs.
  • Sterilizable-in-place sampling valve.

Peristaltic Pumps
  • Four fixed-speed pumps with options for additional pumps.

Optional Features
  • Includes mechanical seals, rotameters, mass flowmeters, and additional impeller packages.
  • Options for remote workstation and various sensors.

Turnkey Projects
BRS Biotech offers customized turnkey solutions for biotech and pharmaceutical plants.

Contact Information
Address: Lubika tee 5, 74117 Maardu, Harju maakond, Estonia
Phone: +372 516 4723
Email: [email protected]
Website: www.brsbiotech.com
Representative in Germany: [email protected], +49 15236853313

Additional Fermenter Types
  • Photobioreactors
  • Solid-phase fermenters
  • Airlift fermenters
See more

Catalog excerpts

PILOT AND IDUSTRIAL FERMENTERS BRS BIOTECH-1

PILOT AND IDUSTRIAL FERMENTERS BRS BIOTECH

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PILOT AND IDUSTRIAL FERMENTERS BRS BIOTECH-2

Pilot and industrial fermenters BRS pilot and industrial scale fermenters are designed for pilot and industrial processes and industrial upscaling. We propose stand-alone units as well as fully equipped lines for biotech and pharmaceutical plants. • Volumes ranging from 15 to 15 000 l. • Pilot and industrial production of agricultural and veterinary chemicals. • Fermenter is platform-mounted. Open frame modular construction gives easy access for maintenance and operation. Central connections for steam, water and air minimize time and work requirements while starting operation. • Power source,...

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PILOT AND IDUSTRIAL FERMENTERS BRS BIOTECH-3

3. Lid lifting system Electrical lid lifting system. The lid is lifted with the agitator shaft and the drive for fermenters less than 1000 liters (Extra option) 4. Agitation Agitation speed 40-800 rpm (depends on fermenter volume) Frequency converter Single mechanical seal Double mechanical seal and magnetic seal Extra option Mechanical defoaming blade on the shaft Height-adjusting agitator impellers, impeller type- Rushton (or marine impeller, pitched blade or the customized impeller) Bumper 5. Temperature control Fully automatic sterilization full and empty vessel Adjustable sterilization temperature...

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PILOT AND IDUSTRIAL FERMENTERS BRS BIOTECH-4

10. Peristaltic pumps 4 peristaltic pumps Watson Marlow with fixed speed in total: Alkali pump Acid pump Defoaming pump Feeding pump Extra pumps with fixed speed and variable speed are available as Extra option 11. Sampling system Sterilizable-in-place sampling valve type 12. Ports (design according to the customer requirements) Temperature sensor port pH sensor port pO2 sensor port Defoaming sensor port CIP spray balls port (in case of installation) Feeding port – 4 needles ports Spare port (upon costomer request) Inoculation port Port for safety valve on the lid Port for safety valve on the...

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PILOT AND IDUSTRIAL FERMENTERS BRS BIOTECH-5

Double mechanical seal Magnetic seal – depends on the fermenter volume Lid Lifting System (up to 1000 liters) N2 rotameter with gas supply line O2 rotameter with gas supply line CO2 rotameter with gas supply line Air automatic mass flowmeter (MFC) N2 automatic mass flowmeter (MFC) O2 automatic mass flowmeter (MFC) CO2 automatic mass flowmeter (MFC) Replacement fixed speed pumps with variable speed pumps Extra pump with fixed speed Extra pump with variable speed Additional impeller package (types of impellers depend on customer requirements) Additional system for injecting media into the vessel...

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PILOT AND IDUSTRIAL FERMENTERS BRS BIOTECH-6

We produce also these types of fermenters: Solid-phase fermenters Fermentors& Bioreactors/Downstream Processing Equipment Lubika tee 5, 74117 Maardu, Harju maakond, Estonia Phone: +372 516 4723 [email protected] Representative in Germany (Hamburg) [email protected] +49 15236853313 www.brsbiotech.com Airlift fermenters

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.