Peptide Synthesis and Purification
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Peptide Synthesis and Purification Systems and Accessories

Delivering Innovative Technologies for Peptide Professionals Contents 3 The Biotage Peptide Family 4 Biotage Initiator+ Alstra 6 Biotage Initiator+ SP Wave 8 Biotage Syro Wave 10 Syro I and Syro II 12 SAP and SAM 14 Biotage Initiator Peptide Workstation 15 Biotage Resolux 16 ChemMatrix 18 Ordering Information ® The global need for custom and synthetic therapeutic peptides is growing, as academic researchers and the pharmaceutical and biotech industries renew their interest in peptide-based drug discovery. As researchers require higher quality peptides in ever greater quantities and...

Automation Microwave Room Temp. Single channel Multiple (Parallel) Scale range per reactor vial (mmol)1 Biotage® Initiator+ SP Wave Biotage® Initiator Peptide Workstation Dependent on resin type and loading

Simplicity of operation using the versatile touchscreen interface. Flexible rack set-up allows reagents to be positioned anywhere. Five reagent bottles allowing different coupling reagents and capping steps during a synthesis. The robot liquid handler dispenses concentrated liquid reagents which allows a lower excess of activated amino acids to be used. Accurate dispensing of reagents using digital syringe pumps. Three external system solvents. Biotage Initiator+ Alstra ® Automated Microwave Peptide Synthesizer The Biotage Initiator+ Alstra is a fully automated microwave peptide synthesizer...

Biotage* Initiator+ Alstra" Specifications Heating Process Temperature range Temperature increase Pressure range Power range Reactor vial sizes Agitation Vial volume range Inert gas (microwave cavity) Inert gas (manifold option) Liquid handling Syringe pump Flow rate Reagent bottles Solvent bottles Amino acid rack Waste bottle 40-100 °C Typically 2-5 °C/s Run at atmospheric pressure 0-120 W at 2.45 GHz 5, 10 and 30 mL Oscillating mixing unit 5 mL (0.6-3.5 mL) 10 mL (3.5-10 mL) 30 mL (4.5-20 mL) Approx. 2 L/min (0.07 cubic feet/min); 0.5 bar (0.05 MPa; 7.25 PSI) Approx. 4 L/min (0.14 cubic...

The intuitive interface provides complete control of the process. Perform small scale microwave synthesis by using single or multistep procedures. The Biotage® SP Wave pump module guarantees accurate liquid dispensing using a digital syringe pump. Biotage® Initiator+ SP Wave Microwave Peptide Synthesizer A versatile and programmable synthesizer that can perform microwave assisted synthesis of both peptides and organic compounds. The system delivers an industry-high 300 °C temperature and safe 30 bar pressure, making this a versatile instrument choice for any lab. The Biotage® Initiator+ SP...

Biotage* I n itiator+ SP Wave Specifications Heating Process Temperature range Temperature increase Pressure range Power range Reactor vial sizes Agitation Vial volume range Inert gas (optional) 40-100 °C Typically 2-5 °C/sec Run at atmospheric pressure 0-100 W from magnetron at 2.45 GHz 2, 5 and 10 mL Vortex unit (500-1300 rpm) 2 mL reactor vial: 0.8-1.1 mL 5 mL reactor vial: 1.6-3.2 mL 10 mL reactor vial: 3.2-6.4 mL Approximately 2 L/min (0.07 cubic feet/min), 0.5 bar (0.05 MPa; 7.25 PSI) Touch screen Ethernet LAN USB Archiving/back-up Printing 10.4" Complies with IEEE 802.3 (ANSI 8802-3)...

Microwave irradiation allows synthesis of sequences that are problematic or even impossible to synthesize using conventional methods. Intuitive Syro XP software controls instrument functions and calculates amounts and volumes of amino acids and reagents. Flexible reactor block formats increase synthesis throughput and result in higher productivity. The precise digital syringe pump guarantees low amino acid and reagent consumption, reducing coupling and running costs compared to other systems. Automated parallel operation allows for synthesis of more peptides in less time resulting in higher...

Biotage* Syro Wave” Specifications System Specifications Heating Automation Syringe pump Reactor block Mixing Vacuum pump Amino acid rack Reagent bottle rack Waste bottle Included equipment Dimensions (W x D x H) Weight Microwave cavity Single robotic arm Single 5 mill-type reactor block for 2, 5 and 10 mL reactor vials. Choice of either 24 or 48 positions Separate vortex mixers for reactor block and microwave cavity ME 2C 32 x 50 mL Falcon tubes 2 x 500 mL, 3 x 200 mL 1 x 10 liter Nalgene bottle Desktop PC, flat panel monitor, printer and Syro XP software 90 cm x 70 cm x 91 cm 85 kg...

Accurate dispensing of exact volumes of all reactants and vortexing of the reaction mixture guarantee the best synthesis results. Automated parallel operation allows for the synthesis of more peptides in shorter times. Flexible reactor block formats increase synthesis throughput and result in the highest productivity. The unique U-block reactor assembly has a truly independent flow path for each reactor vial with no possibility of cross-contamination. 3-tip washcomb for faster washing and dispensing of reagents. Automated Parallel Peptide Synthesizers Syro I and Syro II systems are fully...

Specifications System Specification Automation Liquid handling Mixing Reactor block Vacuum pump Amino acid rack Reagent bottle rack Waste bottle Equipment Dimensions (W x D x H) Weight Syro I Single robotic arm Two 5 mL digital syringe pumps Vortex mixer for reactor block U-type reactor block for 2, 5 and 10 mL reactor vials. Choice of either 24 or 48 positions ME 2C 40 x 50 mL Falcon tubes 2 x 500 mL, 3 x 200 mL 1 x 10 liter Nalgene bottle Includes desktop PC, flat panel monitor, printer, and Syro XP software 56 cm x 70 cm x 91 cm 60 kg Syro II Dual robotic arm with a triple pipetting...

Vortex mixer for effective mixing. Digital syringe pump and eight-way valve ensures accurate dispensing of reagents. Synthesize up to 24 peptides at a time. 0.5–20 mmol scale synthesis Semi-Automated Synthesizers of Single or Multiple Peptides The SAP (Semi-Automated Single Peptide Synthesizer) and SAM (Semi-Automated Multiple Peptide Synthesizer) are user-friendly synthesizers with a high level of flexibility. Single Peptide SAP and SAM are operated using an external controller with an LCD display and six function keys. The controller is used for single commands (i.e. FILL, REACT, EMPTY)...