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Flash Purification Cartridges & Method Development
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Flash Purification Cartridges & Method Development - 1

Flash Cartridge / Instrument Compatibility Table Cartridges & Columns Biotage® SNAP Biotage SNAP Ultra Biotage SNAP XL Biotage ZIP™ Samplet® Dry Load Vessels Flash 75 and Flash 150 Flash 400 Accessories TLC Plates Liquid Sample Injection Valves & Adapters Cartridge Adapters & Holders FlashPack Plunger Assemblies Stationary Phases for Flash Purification Flash purification Method Development Normal-Phase Reversed-Phase

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Flash Purification Cartridges & Method Development - 2

Flash purification cartridges for better, more reproducible separations From routine to highly specialized applications, Biotage® has your solution In 1994, Biotage was the first company to develop pre-packed cartridges for flash purification, and has been the leader in quality, performance and innovation ever since. contents page Compatibility Table Cartridges & Columns Biotage SNAP 4-5 Biotage SNAP Ultra 6-7 Liquid Sample Injection Valves & Adapters Cartridge Adapters & Holders FlashPack Plunger Assemblies Stationary Phases for Flash Purification 17 Flash Purification Method Development...

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Flash Purification Cartridges & Method Development - 3

Automated Systems Manual Systems Scale-up Systems Cartridge Biotage SNAP and Biotage SNAP Ultra Media Mass Biotage Isolera Four Biotage Biotage FlashMaster FlashMaster Personal PersonalPlus Biotage ZIP™ Flash 75S Flash 75M Flash 75L Flash 150M Flash 150L Flash 400M Flash 400L For more information on Biotage flash purification instruments please see our Flash Systems brochure. • = Attaches directly • = Requires external cartridge stand or adapter Flash Purification cartridges & Method Development

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Flash Purification Cartridges & Method Development - 4

Flexibility, performance, and high-value The Biotage SNAP family of flash cartridges is the recognized industry standard for professionals worldwide. Available in a wide range of sizes for practically any situation, Biotage SNAP cartridges deliver the purification efficiency and favorable separation time to meet the growing demands of a global economy. The Biotage SNAP cartridge design enables seven types of loading techniques including three internal dry loading options. They are packed to provide the highest resolution of any 50 μm particle cartridge on the market providing increased...

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Flash Purification Cartridges & Method Development - 5

Advantages • Universal fit onto all flash systems • 3000 N/M minimum performance provides narrower elution bands increasing sample load • Up to 100 psi / 7 bar pressure rating enables faster flow rates and use with viscous solvents • 20% more loading capacity than competitive cartridges • Higher peak resolution than competitive cartridges • Luer-lock connections eliminate adapters and provide compatiblity with most flash systems • Removable cap allows internal sample loading • 3000 N/M minimum performance provides narrower elution bands increasing sample load • Up to 100 psi / 7 bar...

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Flash Purification Cartridges & Method Development - 6

Biotage SNAP Ultra ® The highest purification performance Biotage SNAP Ultra flash chromatography cartridges deliver the highest purification performance available with the highest column loading capacity utilizing Biotage HP-Sphere™, spherical silica delivering 40% more surface area. the highest performance available Precision engineered Biotage SNAP Ultra cartridges deliver double the purification capacity of other flash cartridges by utilizing Biotage HP-Sphere, small particle, 25 µm spherical silica with a 40% increase in surface area. The higher surface area provides twice the loading...

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Flash Purification Cartridges & Method Development - 7

• Biotage HP-Sphere, spherical silica with 40% more surface area delivers the highest sample loading available to reduce purification costs • Smaller, 25 um silica delivers the best peak resolution and higher concentration fractions reducing solvent evaporation time pressure limit Minimum 7000 N/m (plates per meter) Universal Luer connections Tubes: inert, medical-grade polypropylene (USP Class VI) Frits: inert polyethylene • Removable cap provides internal sample loading, both liquid and dry to improve purification performance • Samplet® cartridge compatibility to pre-concentrate samples...

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Flash Purification Cartridges & Method Development - 8

Cartridges for development-scale purification SNAP 750 g and 1500 g cartridges address a growing need for optimized gram-to-150+ g-scale purification, increasing purification efficiency while reducing costs. SNAP XL cartridges are rugged and laser welded for safe operation at pressures up to 100 psi, enabling higher flow rates and the use of higher viscosity solvents. high productivity Operating at flow rates up to 500 mL/min, Biotage SNAP XL cartridges allow you to quickly purify large sample masses, saving hours or even days of purification runtime. direct scale-up With greater than 10%...

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Flash Purification Cartridges & Method Development - 9

recommended instruments • Laser welded for strength and safety • High loading capacity increases purification throughput • Biotage Isolera Four • Seamless scale up from other Biotage flash cartridges • Up to 100 psi / 7 bar pressure rating enables faster flow rates • Compatible with most manufacturers’ development-scale instruments • Translucent barrel provides assurance that solvent is flowing and separation is occurring optional accessories • USP Class VI construction materials minimize extractables providing cleaner purified products • Inlet and outlet Luer fittings • 3-way, large-bore...

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Flash Purification Cartridges & Method Development - 10

Biotage ZIP™ Simplicity, performance and high-value Biotage ZIP flash cartridges are an evolution in Biotage’s long history of manufacturing flash purification solutions. Biotage ZIP cartridges deliver industry-leading performance that meet the difficult challenges of day to day purification. Plug and play Biotage ZIP cartridges are the perfect compliment to all Biotage Isolera™ flash chromatography systems. high performance at a value price Biotage ZIP cartridges are engineered to meet the needs of chemists requiring high performance and consistency from a purification cartridge to ensure...

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Flash Purification Cartridges & Method Development - 11

• 20% more loading capacity than competitive cartridges Tubes: inert polypropylene Frits: polyethylene • Up to 150 psi / 10 bar pressure rating enables faster flow rates and use with viscous solvents • Translucent barrel provides assurance that solvent is flowing and separation is occurring pressure limit • Consistent performance provides reliable results • Laser-welded inlet fitting provides leak-free operation and high pressure tolerance Universal Luer connections, compatible with all flash systems • Luer tip outlet is compatible with all flash systems • Automated manufacturing process...

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