Biotage SPE Dry 96 Sample Concentrator System | Page 1 ® Sample Concentrator System Biotage SPE Dry 96 and SPE Dry 96 Dual Sample Concentrators are suitable for evaporation of microplate samples across a broad range of formats. By delivering heated gas above and below each well, SPE Dry 96 systems dry samples quickly maintaining tight temperature control at user selected settings. Designed for high throughput sample processing, SPE Dry systems have simple front panel controls and use removable gas delivery assemblies for fast adjusting and cleaning. ® Figure 1. SPE Dry 96 with optional Biotage ACT Plate Adapter (left). SPE Dry 96 Dual (right). ® Specifications Versatile Formats SPE Dry is designed with novel technology and a simple interface to produce uniform and reproducible evaporation. The design has a small footprint to fit easily in the fume hood. The heating mechanism is designed to rapidly heat without overshooting the temperature, preventing degradation of temperature sensitive compounds. Heated gas delivery above and below wells speeds evaporation Models for one or two 96 well plates 8 x 12 well microplates and deep-well plates Standard SPE Dry 96 and SPE Dry 96 Dual systems are supplied with stainless steel needles. For high purity work, or applications that require particularly aggressive solvents, PTFE coated needles are available. Both needle types can be individually replaced should they become damaged or corroded. SPE Dry is available in single or dual format and adapts easily to 24-, 48-, 96-, and 384-well microplate formats. Final Endpoint Volumes Operating Temperature 60 °C (upper head) 80 °C (lower head) Operating Flow Rate Electrical Supply Advantages » Efficient evaporation through heated gas Dimensions (WxDxH) flow above and below collection plate Precise temperature control and gas flow with reproducible evaporation times Compact design Easy to use Suitable for 24-,48-, 96- and 384-well mi

Biotage® SPE Dry 96 Sample Concentrator System | Page 2 1. Experiments were conducted with flow rate at 50 liters/minute at the upper manifold and 30 liters/minute at the lower manifold. Drying gas used was compressed air. Only standard moisture trap was used within the system. Moisture content of ambient air will affect results. 2. Temperatures refer to the upper head. Bottom unit was 20 °C higher. 3. 500 pL volumes were in a 1 mL collection plate. 4. 1 mL volumes were in a 2 mL collection plate. Biotage® ACT Plate Adapter Protect your samples from cross contamination (cross talk) during evaporation....