• Biotage® PhyPrep Biotage PhyPrep

High yield plasmids. Less hassle. Total confidence. Intuitive workflow High purity, low endotoxin, Minimal setup with pre-filled buffers and touchscreen control Hands-free operation Reliable results Load sample, press start, Consistent yield and purity every walk away

Automated plasmid purification - from Maxi to Giga scale | © Biotage 2025 Scalable automation for your growing demands From Maxi to Giga preps, Biotage PhyPrep scales effortlessly with your research needs ® –delivering up to 10 mg of plasmid DNA per run with walkaway automation. Whether you’re running a few samples or scaling up for production, Biotage PhyPrep is the only automated ® plasmid purification system that grows with your lab. Biotage PhyPrep workflow ® Plasmid production Plasmid purification Transient transfection of cells Purifications of proteins or viral vectors Sample preparation...

Focus on delivery. Not prep time. Manual plasmid purification is slow, inconsistent, and resource-intensive, especially at scale. Biotage PhyPrep simplifies the process, delivering ® high-purity plasmid DNA from cell pellets at Maxi, Mega, and Giga scales. Let Biotage PhyPrep handle the plasmid purification consistently, cleanly ® and hassle-free. You can stay focused on designing experiments, analyzing data, and driving biologic results. Plasmid yield 1 mg (MaxiPrep) / 5 mg (MegaPrep) / 10 mg (GigaPrep)

Automated plasmid purification - from Maxi to Giga scale | © Biotage 2025 Reduce sample prep time by up to 40% and accelerate your discovery pipeline. 5

Dual flow chromatography for consistent results We know that when it comes to plasmid quality, there’s no room for compromise. Using our proprietary dual flow chromatography technology, Biotage PhyPrep ensures high quality DNA. ® This highly pure plasmid DNA is suitable for many downstream applications, such as transient transfection, protein expression, gene therapy, DNA sequencing and vaccine development. Plasmid Plasmid Resin Bottom screen Impurities Impurities

Automated plasmid purification - from Maxi to Giga scale | © Biotage 2025 Dimer plasmid — SC plasmid Figure 1. Electrophoresis analysis of plasmid integrity shown on a 1% EtBr agarose gel of three Biotage® Maxi, Mega and Giga scale PhyPrep runs. All samples were nomralized to 100ng of nucleotide per well from individual purification runs along with a leading competitor as a control in lane 12. The main product is supercoiled (SC) plasmid with the alternative plasmid dimer form.

Biotage' PhyPrep Part number Description Qty © 2025 Biotage. All rights reserved. No material may be reproduced or published without the written permission of Biotage. Information in this document is subject to change without notice and does not represent any commitment from Biotage. E&OE. A list of all trademarks owned by Biotage AB is available at www.biotage.com/legal. Other product and company names mentioned herein may be trademarks or registered trademarks and/or service marks of their respective owners, and are used only for explanation and to the owners' benefit, without intent to infringe....