FLOWSTAR² LB 514 Radio Detector for HPLC

BERTHOLD TECHNOLOGI FLOWSTAR2Maximum flexibility, outstanding sensitivity With over 50 years of experience Berthold Technologies is taking radio-HPLC flow detection to the next level. Designed for maximum ease of use, safety and flexibility the FlowStar2 LB 514 sets the new standard for what a radio-HPLC flow detector should be. A wide range of available cells ensures optimal performance and supports full compatibility with both, routine and challenging applications. The convenient dual mode capability enables simple installation in different configurations and makes integration into existing...

APPLICATIONS & TECHNOLOGIES Superior performance for both routine and challenging applications Pharmaceutical Analysis Radio-HPLC is a key technology for the separation and quantitation of radiolabeled drugs and putative metabolites in drug development. Environmental Analysis A wide variety of contaminants from sources such as industrial waste, landfill sites, pesticides and phar­­­ma­ceutical drugs can make their way into the environment. The challenging identification of these contaminants demands for highly-sensitive detectors to enable detection of lowest concentrations. Development and QC...

BERTHOLD TECHNOLOGI

Safe & Secure User-friendly The FlowStar2 LB 514 is designed to be intuitive and easy to use to get you up and running quickly. ■ INTUITIVE INTERFACE The intuitive touch screen interface makes it easy to get started and keep going. Results are displayed in both, a graphical chromatogram and a numerical format so you can start interpreting your results in real time while the run is still in progress. ■ SMART CELL DESIGN All measuring cells are equipped with a chip to automatically set the correct cell-specific system parameters. ■ PREDIFINED RUN PARAMETERS Extensive isotope library with predefined...

BERTHOLD TECHNOLOGI Choose from a wide range of available SmartCells to meet your application needs. These high sensitivity cells are equipped with a SmartChip to automatically set the correct cell-specific system parameters. The automatic shut-down feature of the system after removal of a cell from the detector provides additional safety. Standard Fingertight Fittings Easy system integration Measuring Cells Overview ■ Liquid scintillation (admixture) cells ■ Microbore ■ LC/MS ■ Gamma Isotopes and Positron ■ Emitter (PET) Cells ■ Solid Scintillator ■ Preparative SFC ■ Special Iodine Cells ■ Cherenkov...

Solid Scintillation Cells Liquid Scintillation Cells DESIGN: Consists of a very thin Teflon or Halar hose filled with fine scintillator grains. Designed to withstand backpressure from viscose eluates and flow rate. Solid scintillation cells are available either untreated (YG-U type) or surface treated (YG-S type) to minimise memory effects by sticky analytes. DESIGN: Designed to be used with the homogeneous method when liquid scintillator is added externally using a scintillation pump. Liquid scintillation cells are available for all applications including standard HPLC, LC/MS microbore and UHPLC....

Standard flow rate and activities for lower flow rate or higher activities use Z 200 for higher flow rate or lower activity use Z 1000 Standard flow rate and higher activities Standard flow rate and activities for lower flow rate or higher activities use Z 200 for higher flow rate or lower activity use Z 1000 Standard flow rate and activities Samples with sticking problems use YG 150-S6D for higher flow rate or lower activity use YG 400 ■ General ■ Tritium labeled sample ■ Preparative samples ■ Purification samples ■ Quality control samples (highest activity) ■ Peptides, proteins high molecular weight...

ACCESSORIES To meet your specific application needs Liquid Scintillator Pump LB 5037 For admixture applications, where a liquid scintillator is continuously mixed with the column eluate. n INSTRUMENT SAFETY – pump separated from the main detector, eliminating the possibility of scintillator leaking into the detector and associated electronics. lt is also possible to split the eluate stream prior to mixing. OF USE – the dual piston pump is completely controlled by the FlowStar2 LB 514 for automatic handling of flow rates and start/stop signals. In addition the system uses a specific ramp function...

BERTHOLD TECHNOLOGI Test Cells Several test cells are available to perform periodic system performance tests. These cells have been developed to meet GLP/GMP requirements and to guarantee a continuous system performance. ■ SIMPLE - The instrument firmware includes specific test functions to check the system performance when using the test cells. The system performance tests are simple to run since all required parameters have been stored in the test cell Smartchip and tests run automatically. ■ SAFE - All results are saved automatically in the instruments memory for further inspection. Inspection...

Static Mixer Mixing the eluate with the liquid scintillator is one of the key issues in radio-HPLC and can influence the quality of the results directly. We offer a static mixer to improve the mixing. Two different mixing cartridges are available with a dead volume of either 50 μl or 150 μl. Splitters and waste valve Valveless Splitters are available to split the eluate before mixing with scintillator, allowing part of the eluate to be diverted to a fraction collector. WASTE MANAGEMENT – a waste valve diverts the radioactive peak to a fraction collector and the non-radioactive waste to a low...

BERTHOLD TECHNOLOGI Flow Plus Flow Plus has been formulated to meet the special requirements of radio-HPLC, in particular the counting of solvent/water gradients when using a Z-cell with the FlowStar2 LB 514. The formulation of Flow Plus has been optimised for counting aqueous/solvent gradients from 100% water to 100% solvent at high sample-to-scintillator ratios in flow cell applications. ■ Low viscosity, non-gelling ■ Suitable for solvent/water gradients ■ Buffer gradient capability for HPLC Flow Safe 2 Flow Safe 2 is a scintillation cocktail for use in flow counting, especially in combination...