Introduction
AstraZeneca, a leading pharmaceutical company with operations in over 100 countries, partnered with Beamex to implement an automated and validated calibration system across its Swedish operations. This initiative aimed to enhance efficiency and compliance in calibration processes.

Background and Requirements
The initial situation at AstraZeneca Sweden Operations was challenging due to the extensive number of calibrations required annually, approximately 21,000. The company sought a system that would reduce calibration time and production downtime, highlight adverse trends, and provide easy access to data. The goal was to eliminate manual errors and streamline processes across multiple databases and workflows.

Solution Implementation
AstraZeneca adopted Beamex's CMX calibration management software, including the server version with a Pocket PC option and MC5 Multifunction Calibrators. This setup allowed for uniform calibration processes, replacing manual verifications with automated, validated procedures. The system supports data entry via PDAs and centralizes data access across multiple sites.

Main Benefits
The implementation of CMX resulted in a more efficient and cost-effective calibration process. It enabled the automatic production of fully auditable and traceable calibration certificates, compliant with 21 CFR Part 11 regulations. The system's History Trend function aids in identifying performance trends, allowing for adjustments in calibration frequency.

Conclusion
The new calibration system at AstraZeneca Sweden Operations has significantly improved workflow efficiency and compliance, providing a short payback period for the project. The collaboration with Beamex has set a benchmark for automated calibration processes in the pharmaceutical industry.