Biopharmaceutical Shipping - Bio-pharmaceutical products shipped frozen from UK to destinations throughout Europe Bio-pharmaceutical products shipped frozen by common carrier (courier and airfreight) from UK to destinations throughout Europe. Materials are ship-ped Mon-Thursday on a two-shift basis. 2x Triventek PE80 Pelletizer (8mm extrusion plates) 2x Triventek RE80 Recovery Units 2x Bitzer LH104/4TCS8.2Y Condensers* Installation date: Bought-in dry ice: Estimated excess wastage bought-in over on-site: Triventek Equipment: Liquid CO2: Vessel rental: Installation**: Cash Payback: Dry Ice cost after payback: Ongoing cost reduction: Dry Ice cost after payback: Ongoing cost reduction: Aquila Triventek A/S · Industrivej 9 · DK-5580 Nørre Aaby · Tel. +45 70 22 12 92 · [email protected] · www.aquila-triventek.com

Biopharmaceutical Shipping - Bio-pharmaceutical products shipped frozen from UK to destinations throughout Europe Internal rate of return: Operating profit before depreciatio: Years payback: Installation: Approximately 6m x 2m space was found within 10m of the packing stations, and next to the liquid nitrogen bay for the installation of the PE80 and RE80 equipment Recovery Units during installation The vessel was located immediately outside with approx 10m of insulated pipework running from the front of the horizontally-arranged tank. A hard-standing was made for the external Bitzer condensers...

Biopharmaceutical Shipping - Bio-pharmaceutical products shipped frozen from UK to destinations throughout Europe Operation: Packaging Department management and opera-tives expressed their satisfaction on the following points: • Cost reduction • Waste reduction: it was estimated by packaging staff that previously approx 25% of bought-in dry ice had to be thrown away, having been over-ordered to cover fluctuations in demand. It was estimated that 5% of on-site produced dry ice needed to be ‘over-produced’ to cover unexpected eventualities. This is calculated as 20% excess waste for bought-in compared...

Biopharmaceutical Shipping - Bio-pharmaceutical products shipped frozen from UK to destinations throughout Europe | • Labour time to start-up the equipment and to replace filled boxes was thought to be negligible, and similar to time unloading bought-in boxes, ordering etc. i • One unexpected fault occurred within two weeks of commissioning when a high pressure cooling alarm was triggered. This was dealt with by opera-tives with phone support from the factory. ! • Simple non-powered wall ventilation proved adequate and no instances of excess gas concentra-tion, or triggering of the exhaust system,...