MicroPoint 4

MicroPoint 4

MicroPoint 4

Product catalog summary
Introduction
MicroPoint 4 is a cutting-edge laser scanning-based illumination system by Andor, designed for precise photostimulation in research applications such as axotomy, DNA damage induction, optogenetics, FRAP, and uncaging. It features a smart microcontroller and supports both continuous and pulsed lasers across 24 laser dye cells ranging from 365 to 656 nm.
Key Features
  • Supports both pulsed and continuous wave lasers with over 24 customizable wavelengths.
  • Compatible with most microscopes, offering manual and PC-controlled Galvo models.
  • Enhanced optical design and new laser engine compatibility for improved performance.
  • Fast scanning galvos for precise beam steering and scanning.
Applications
  • Ablation and Microdissection: Used for precise ablation in studies like V3-Interneurons in zebrafish.
  • DNA Repair Studies: Induces double strand DNA breaks to study repair pathways, demonstrated in Caenorhabditis elegans.
  • FRAP: Utilized for fluorescence recovery after photobleaching to study protein dynamics.
Technical Data
  • Laser sources include Nitro Dye Laser, Pico Laser, VLE, and HLE options with varying power and pulse specifications.
  • Control options include manual and smart controllers with software compatibility for life science applications.
Configurations
MicroPoint 4 can be configured with additional light sources for fluorescence and imaging setups, supporting integration with Andor's Mosaic for multi-target optogenetics and photo-conversion.
Ordering Information
Detailed steps are provided for selecting components such as control interfaces, lasers, dye cells, and accessories to customize the MicroPoint 4 system for specific research needs.
Overview
The document outlines technical specifications and configuration options for the MicroPoint 4 laser system, including details on laser dyes, interlock selection, EPI combiner blocks, beam splitters, and system components.
Laser Dyes
The system supports pre-mixed laser dyes identified by the code MP-27-XXX-DYE, where XXX represents the wavelength. Available wavelengths include 365, 388, 390, 404, 422, 435, 471, 481, 514, 521, 539, 543, 551, 576, 582, 590, 593, 613, 622, 626, 651, and 656 nm.
System Configuration
  • Laser Interlock: Selection is based on the laser and system configuration.
  • EPI Combiner Blocks: Options include left-hand BSP block & heat filter (MM-7239-L-LLB) and right-hand BSP block & heat filter (MM-7239-R-LLB).
  • Beam Splitters/Combiners: Various configurations are available, such as T100%, R50-T50%, R100%, and others, with specific transmission and reflection ranges.
Product Specifications
  • Controller: Manual controller weight is 350 g, and the MicroPoint 4 controller weighs 1.55 kg.
  • Optical Head: Weights vary by model, with the Nitro Galvo at 1.8 kg and the Pico Galvo at 2.8 kg.
Operating Conditions
  • Temperature: 18 °C to 28 °C
  • Humidity: < 70% (non-condensing)
  • Storage Temperature: -20 °C to 50 °C
Power Requirements
The system requires 120-240 VAC, 50-60 Hz, with a power consumption of 30 W/50 W (typical/maximum).
Safety and Compliance
The system is classified under HLE Class 4 and VLE Class 3B laser safety standards. It is available for research and development purposes within the EU, adhering to the EU RoHS Directive.
Included Items
The package includes various cables, a power supply, a USB with Andor iQ software, and other accessories necessary for operation.
Contact Information
Regional headquarters are located in Europe, Japan, North America, and China, with contact details provided for each location.
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Catalog excerpts

MicroPoint 4-1

MicroPoint 4 A Powerful Tool for Laser Photostimulation Key Features Pulsed and CW lasers: flexible Optogenetics, FRAP Galvo or manual: budget friendly Fast galvos: agile point and scan Cell and Developmental Biology Fits most microscopes: very configurable Cancer Studies NEW Laser engine compatibility Semiconductor Marking

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MicroPoint 4-2

Introduction | Applications | Technical Data | Interface | Ordering | Drawings MicroPoint 4 is the 4th generation of Andor’s popular laser scanning-based illumination system for photostimulation applications. MicroPoint is a proven choice for hundreds of research studies around the world for applications that require precise illumination including: • • • • • Axotomy, microdissection and ablation: study repair and regeneration processes. Induce DNA damage: for DNA repair, regulation and gene function. Optogenetics: study the role of individual neurons within complex networks. Bleach and FRAP:...

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MicroPoint 4-3

Introduction | Applications | Technical Data | Interface | Ordering | Drawings Application Focus Illuminate your Research with MicroPoint 4 MicroPoint 4 can be used for a wide range of experiments that incorporate photostimulation based techniques. Study fundamental processes of cell biology within individual cells, tissues or in the full organism context within small animal models. Double Strand DNA Breakages - DNA Repair Studies MicroPoint is ideal for supplying the precise, focused illumination needed for inducing double strand DNA damage and studies of the repair pathways. In this example,...

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MicroPoint 4-4

Introduction | Applications | Technical Data | Interface | Ordering | Drawings Flexible Configurations Technical Data MicroPoint 4 can be configured with other light sources such as Epi illumination for fluorescence and even confocal and TIRF imaging setups. For ultimate flexibility, Andor’s Mosaic DMD-based tool can be integrated for simultaneous multi-target optogenetics, photo-conversion and switching. The images below shows basic configurations for MicroPoint 4. The BSP (beam splitter plugs) and MicroPoint filter cubes are used to mix light from the MicroPoint and EPI light sources for photostimulation...

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MicroPoint 4-5

Introduction | Applications | Technical Data | Interface | Ordering | Drawings Choose your Control Interface MicroPoint 4 Manual - Manually Controlled Laser Illumination MicroPoint 4 Galvo - Flexible, Scanned Laser Illumination Both Nitro and Pico versions can be configured with galvanometers. The laser dye cell provides multiple laser wavelengths. Galvo models can also be combined with a range of CW lasers using the fibre spot adapter. MicroPoint 4 easily integrates with many supported microscopes with factory‑installed focus modules enabling optimal performance. Beam steering and software gives...

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MicroPoint 4-6

Introduction | Applications |Technical Data | Interface | Ordering | Drawings Ordering your MicroPoint 4 System Below is an overview of the system configuration options, your sales representative will discuss your application to ensure your configuration meets your needs Step 1. Choose your control interface, laser and microscope. Select one of these or none if FSA only Galvo for Nitro dye laser and/or FSA - see page 8 EPI Filters Core Unit COMING SOON Galvo for Pico laser - see page 8 Manual for Nitro dye laser and/or FSA - see page 9 Add optional CW laser if required Step 3. Pulsed Lasers Step...

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MicroPoint 4-7

Introduction | Applications | Technical Data | Interface | Ordering | Drawings Product Drawings MicroPoint 4 Nitro Galvo with FSA Optical Head Weight = 1.8 kg (4 lb 1oz) MicroPoint 4 Controller Controller Weight 1.55 kg (3lb 3oz) LCD Touchscreen Unit (for manual MicroPoint models only) Manual Controller Weight 350 g (12 oz) SIDE VIEW REAR VIEW

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MicroPoint 4-8

Introduction | Applications | Technical Data| Interface | Ordering | Drawings MicroPoint 4 Pico Galvo with FSA MicroPoint 4 Nitro Manual with FSA Optical Head Weight = 2.8 kg (6.2 lb) including laser Optical Head Weight = 1.4 kg (3.0 lb)

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MicroPoint 4-9

Order Today Need more information? At Andor we are committed to finding the correct solution for you. With a dedicated team of technical advisors, we are able to offer you one-to-one guidance and technical support on all Andor products. For a full listing of our local sales offices, please see: andor.oxinst.com/contact Our regional headquarters are: Europe Japan Belfast, Northern Ireland Tokyo Phone +44 (28) 9023 7126 Phone +81 (3) 6744 4703 Fax +44 (28) 9031 0792 Fax +81 (3) 3446 8320 North America China Concord, MA, USA Beijing | Shanghai | Guangzhou Phone +1 (860) 290 9211 Phone +86 (400)...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.