etoN lacinhceT Luca-R EMCCD vs. Interline CCD for cell microscopy applications 70-ceD- 31 esU lanr etxE Technical Note

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Results Under restricted signal conditions, derived through use of low laser power and/or short exposures, the Luca R significantly out-performed the interline CCD sensor, both in terms of Signal-to-Noise and resolution (because the latter is highly influenced by the former) as shown in Figure 1. Application of EM Gain of the Luca-R serves to amplify the weak signal above the read noise floor, thus drastically improving contrast and definition of fine structural features inside the imaged cell. The lower sensitivity of the interline CCD camera is due primarily to the influence of the read noise...

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