Pilot plant separation system BTPX 205 The key to success in bridging the gap from the laboratory to commercial production is a pilot plant that delivers results that will be relevant when you move into full-scale production. Scaling up involves compromises that often cannot be predicted in the laboratory. BTPX 205 is a fully automatic, plug-in, separation system. It delivers the performance of production machines on a pilot scale, and is designed specifi cally for cell harvesting, broth clarifi cation and cell debris separation. Hygienic design The design of the BTPX 205 is exceptionally hygienic. It is steam sterilizable and has cleaning-in-place capability. A specially designed seal system provides effi cient containment and eliminates the risk of product or environmental contamination. Cooling jackets surrounding the centrifuge bowl give effi cient temperature control and also contribute to a low noise level. The “dosing ring” solids-ejecting system with fast and distinct discharge action ensures low product losses and drier solids. Flushing nozzles spray the outside of the centrifuge bowl and the inside of the frame hood for maximum hygiene. Complete system The BTPX 205 separation system consists of a solids-ejecting centrifuge, type BTPX 205SGD-34CDP with timer-triggered discharge and fi xed discharge volume. The centrifuge is mounted on a fi xed base frame, which includes process pipings for service liquids and process liquids entering and leaving the centrifuge. Typically, the solids phase is removed by a steam sterilizable pump. The built-in electrical system includes starter, PLC control system and pneumatic unit. Materials All liquid-wetted parts are made in high-grade stainless steel. Gaskets are made of Nitrile, Viton or EPDM elastomer as required. Available models The BTPX 205 centrifuge is available as concentrator, purifi er or clarifi er in either standard or explosion-protected execution. The small size but high performance of the BTPX 205 separation system makes it ideal for pilot plants and small scale production.

Working principles The feed is introduced to the rotating centrifuge bowl (fi g 1) from the top via a stationary inlet pipe (1), and is accelerated in a distributor (2) before entering the disc stack (3). It is between the discs that the separation of the liquid phase and the solids phase takes place. The liquid phase moves towards the centre of the bowl from where it is pumped out under pressure by means of a built-in paring disc (4). The heavier solids phase is collected at the bowl periphery, from where it is discharged intermittently via the centrifuge cyclone. The solids discharge is achieved...