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Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS

Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS
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Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS

Product catalog summary
Overview of Agilent 8900 Triple Quadrupole ICP-MS
The Agilent 8900 Triple Quadrupole ICP-MS (ICP-QQQ) is a second-generation instrument designed for reliable interference removal and multi-element analysis. It is suitable for various applications, including routine contract analysis, research, and materials analysis. The system combines the performance of Agilent's quadrupole ICP-MS with MS/MS mode for controlled interference removal, making it a powerful tool for accurate and consistent results.
Key Features and Capabilities
  • MS/MS Advantage: The MS/MS mode allows for precise interference removal using reaction gas methods, enhancing the accuracy and consistency of results.
  • Proven Technology: The ICP-QQQ technology is widely used in semiconductor manufacturing, food safety, environmental monitoring, nanoparticle characterization, life sciences, and geology.
  • Ultra High Matrix Introduction (UHMI): Increases matrix tolerance up to 25% total dissolved solids, allowing for routine measurement of high matrix samples.
  • Advanced Sample Introduction and Gas Control: Features a low-flow, Peltier-cooled sample introduction system and a four-channel argon mass flow control for plasma gases.
  • High Sensitivity and Fast Analysis: The system offers high sensitivity and fast time-resolved analysis, suitable for nanoparticle characterization and other applications.
Applications and Benefits
  • Semiconductor and Materials: Monitors ultratrace contaminants to ensure high product yield and minimize failure rates.
  • Food Safety: Efficiently removes interferences for accurate measurement of arsenic and selenium at lower levels.
  • Environmental Monitoring: Provides low detection limits for trace level contaminants, essential for monitoring emerging contaminants.
  • Nanoparticle Characterization: Capable of measuring nanoparticles at sub-50 nanometer scale, even in complex samples.
  • Geology and Geochronology: Separates direct isobaric overlaps, enabling accurate isotopic analysis.
Software and Automation
The ICP-MS MassHunter software offers an intuitive interface with features such as preset methods, automation, and compatibility with Agilent's Mass Profiler Professional for detailed statistical evaluation. It supports automated startup checks, method setup, sequencing, and integrated data processing.
Introduction
The document provides an overview of Agilent's ICP-MS MassHunter software and its capabilities for nanoparticle and single cell analysis. It highlights the features of the Single Nanoparticle Application Module, which includes preset methods for single particle analysis and field-flow fractionation.
Specifications and Features
The module supports rapid multi-element nanoparticle analysis, allowing for the determination of multiple analytes from a single sample. It includes a Method Wizard for automating setup and calibration, and an integrated tool for calculating nebulization efficiency.
Speciation Capability
Agilent offers comprehensive speciation systems for ICP-QQQ, including LC, GC, CE, IC, and FFF. These systems are designed to meet regulatory requirements in various industries, providing accurate quantitative analysis of difficult-to-measure elements.
Options and Accessories
The document describes various accessories such as the SPS 4 Autosampler, Agilent I-AS Autosampler, and Integrated Sample Introduction System (ISIS 3). It also mentions the availability of different nebulizer options and an inert sample introduction kit.
Software Integration
Agilent's software developer's kit (SDK) allows for the integration of third-party accessories into ICP-MS MassHunter workflows, enhancing the capabilities of the ICP-MS operation.
Additional Information
The document concludes with information on Agilent's CrossLab services, which aim to improve lab efficiency and operations. Contact information and resources for further assistance are provided.
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Catalog excerpts

Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS-1

Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS

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Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS-2

Put Your ICP-MS Results Beyond Doubt Reliable interference removal is easier to achieve with the 2nd generation Agilent 8900 ICP-QQQ. In 2012, Agilent released the Agilent 8800, the world’s first triple quadrupole ICP-MS (ICP-QQQ) with MS/MS capability. This ground-breaking instrument created new analytical possibilities for analysts in hundreds of laboratories around the world. The 2nd generation Agilent 8900 ICP-QQQ suits a range of situations, from routine contract analysis to research, and materials analysis. The 8900 ICP-QQQ has the helium mode performance and productivity of Agilent’s market-leading...

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Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS-3

Proven ICP-QQQ Technology Agilent’s unique triple quadrupole ICP-MS uses MS/MS, enabling hundreds of labs around the world to do more than ever before. Life science and biopharma Dissolved metal and particulate contamination of process chemicals and materials is a major issue for semiconductor manufacturing. ICP-QQQ is used to monitor lower levels of ultratrace contaminants in raw materials, bulk chemicals, and wafer processing baths to ensure high product yield and minimize failure rates. Accurately measuring trace level contaminants in the environment is more important than ever. Agilent ICP-QQQ...

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Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS-4

Be Sure With ICP-MS/MS The Agilent 8900 ICP-QQQ provides outstanding performance for existing multi-element ICP-MS applications. The 8900 also introduces analytical capabilities not previously possible using ICP-MS. Low-level determination of previously difficult elements, separation of direct isobaric overlaps, and fast, trace analysis of emerging nano-scale materials extend the application of ICP-MS into new fields of analysis. Ultratrace analysis of Si and S Resolve isobaric overlaps Si and S suffer from intense polyatomic interferences and have not previously been possible to measure at ng/L...

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Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS-5

Accurate analysis of sulfur and sulfur isotope ratios using MS/MS Nanoparticle (NP) characterization using single particle/cell ICP-MS (sp/scICP-MS) Using O2 cell gas, S can be measured as the product ion SO+ at m/z 48 (for the major 32S isotope), 49, and 50. Measurement of multiple isotopes allows S isotope ratio analysis and accurate quantification using isotope dilution (ID). The 8900 ICP-QQQ with MS/MS is essential for this application, as carbon, calcium and titanium can cause interference when the SO+ product ions are measured without MS/MS, as illustrated, following. The 8900 ICP-QQQ provides...

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Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS-6

Leave Interferences Behind With MS/MS Ultra High Matrix Introduction (UHMI) UHMI increases matrix tolerance up to 25% total dissolved solids (TDS). UHMI is standard on the 8900 Standard and Advanced Applications configurations, ensuring high matrix samples can be measured routinely, and eliminating matrix suppression. Sample Introduction Low-flow, Peltier-cooled sample introduction system provides stability and consistency. Optional Integrated Sample Introduction System (ISIS 3) adds a piston pump and close-coupled 7-port valve for high-speed discrete sampling. Gas Control Four channel argon...

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Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS-7

First Quadrupole Mass Filter (Q1) High frequency, hyperbolic quadrupole mass filter. In MS/MS, Q1 operates at 0.7 u resolution, rejecting all masses except the target analyte mass, and so controlling reaction chemistry in the cell. 4th-Generation Octopole Reaction System (ORS4) Temperature-controlled collision/reaction cell with a 4-channel gas controller for flexibility in cell gas methods. Operates in helium (He) mode and also provides effective, consistent control of interferences in reaction mode with MS/MS. Axial acceleration (Advanced Applications and Semiconductor configurations) enhances...

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Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS-8

Powerful, Flexible, Intuitive ICP-MS Software Preset methods and automation ICP-MS MassHunter software uses an intuitive Task Navigator and toolbar layout, making it easy to learn and use: – The home tab provides easy access to common setup and operation functions, such as Startup, Batch, and Acquisition Queue. – he acquisition pane brings together tune settings, T element selection, and acquisition parameters. IntelliQuant Assistant preselects preferred cell modes for each analyte, providing even simpler method setup. – he sequence pane contains the sample list, and the T queue pane displays...

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Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS-9

Extend Your Nanoparticle or Single Cell Analysis Preset methods for nanoparticle and single cell analysis ICP-MS MassHunter’s optional Single Nanoparticle (NP) Application Module includes preset methods for both single particle analysis (spICP-MS) and nanoparticle analysis using field-flow fractionation (FFF-ICP-MS). Measurement of the metal content of single cells (scICP-MS) is also supported. The spICP-MS Method Wizard uses predefined and user-entered values to calculate essential method variables. Calibration of particle size and number is performed automatically using the analysis of specific...

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Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS-10

Proven Speciation Capability Integrated speciation with ICP-QQQ Fully heated GC interface Environmental, food safety, pharmaceutical, and consumer product regulations increasingly require the identification and quantification of elemental species as well as total concentrations. Agilent offers the most comprehensive range of integrated speciation systems and methods for ICP-QQQ, including LC, GC, CE, IC, FFF, and more. Agilent’s unique GC-ICP-MS interface is heated to the tip of the injector (up to 300 ºC) for routine analysis of high-boiling point compounds. The flexible transfer line and torch...

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Leave Interferences Behind With MS/MS. Agilent 8900 Triple Quadrupole ICP-MS-11

SPS 4 Autosampler A great choice for medium- and highthroughput applications, with rack configurations providing up to 360 vial positions. Integrated cover protects samples from dust and airborne contamination. Agilent I-AS Autosampler with pumped rinse station Agilent Integrated Sample Introduction System (ISIS 3) Ideal for ultratrace analysis in high purity semiconductor chemicals, and for analysis of small sample volumes (0.5 mL). Flexible rack configurations offer a maximum capacity of 89 vials, plus 3 rinse vials. High-speed uptake pump, and closecoupled 7-port switching valve provide fast...

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