,• BIO-DIS Reciprocating Cylinder Apparatus The BIO-DIS Reciprocating Cylinder Apparatus is ideal for automatic dissolution profiling of extended release dosage forms • requiring USP Apparatus 3 and EP reciprocating cylinder testing. Key Benefits ► Biorelevant. Simulate gastrointestinal conditions with simple programming that allows in vitro dissolution pH profiling with biorelevant agitation rates and retention times. ► Flexible. Use one instrument to test and transport a variety of samples, saving valuable bench space. Samples are automatically transported from one medium to the next without operator intervention. ► Compliant. Be confident knowing the BIO-DIS is compliant with the reciprocating cylinder apparatus, USP Apparatus 3 and EP harmonized specifications. ► Easily configured. Select a standard volumetric reciprocating cylinder option or small and large volume configuration to meet testing needs for low dose or poorly soluble formulations.

Agilent’s BIO-DIS Reciprocating Cylinder Apparatus for USP Apparatus 3 is ideal for extended release products or any dosage form requiring release profiling at multiple pH levels. Capable of running unattended for periods of up to six days, the unit can store up to 15 programs. The BIO-DIS allows almost any aspect of a test to be programmed including agitation speed, time in each row, hold dip time, and drain time. Operation The seven sample inner tubes can sequentially traverse the six rows of corresponding outer tubes as programmed. The outer tubes are filled with media and the BIO-DIS transports...

Ordering Information Product DescriptionPart Number BIO-DIS Reciprocating Cylinder Apparatus, 115 V, 60 Hz 25-1000 — To learn more about Dissolution Testing, visit us at www.agilent.com/lifesciences/ dissolution BIO-DIS Reciprocating Cylinder Apparatus, 230 V, 50 Hz 25-1100 Accessory Ordering Information Product DescriptionPart Number BIO-DIS conversion kit, 100 mL 27-6100 BIO-DIS conversion kit, double row dip, 300 mL 27-6200 BIO-DIS conversion kit, double row dip, 1 L 27-6202 BIO-DIS conversion kit, double row dip, 1 L/300 mL 27-6204 Modified versions of the...